Zobrazeno 1 - 7
of 7
pro vyhledávání: '"David Zaragoza-Huesca"'
Autor:
David Zaragoza-Huesca, Maria Carmen Rodenas, Julia Peñas-Martínez, Irene Pardo-Sánchez, Jorge Peña-García, Salvador Espín, Guillermo Ricote, Andrés Nieto, Francisco García-Molina, Vicente Vicente, Maria Luisa Lozano, Alberto Carmona-Bayonas, Victoriano Mulero, Horacio Pérez-Sánchez, Irene Martínez-Martínez
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115814- (2023)
Recently, our group identified serine-protease hepsin from primary tumor as a biomarker of metastasis and thrombosis in patients with localized colorectal cancer. We described hepsin promotes invasion and thrombin generation of colorectal cancer cell
Externí odkaz:
https://doaj.org/article/3c1e41ad623449c197e68a3ce72e012a
Autor:
Maria Carmen Rodenas, Julia Peñas-Martínez, Irene Pardo-Sánchez, David Zaragoza-Huesca, Carmen Ortega-Sabater, Jorge Peña-García, Salvador Espín, Guillermo Ricote, Sofía Montenegro, Francisco Ayala-De La Peña, Ginés Luengo-Gil, Andrés Nieto, Francisco García-Molina, Vicente Vicente, Francesco Bernardi, María Luisa Lozano, Victoriano Mulero, Horacio Pérez-Sánchez, Alberto Carmona-Bayonas, Irene Martínez-Martínez
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Introduction: Hepsin is a type II transmembrane serine protease and its expression has been linked to greater tumorigenicity and worse prognosis in different tumors. Recently, our group demonstrated that high hepsin levels from primary tumor were ass
Externí odkaz:
https://doaj.org/article/0a0bec65f1084dbb942a08af8b945209
Autor:
David Zaragoza-Huesca, Pedro Garrido-Rodríguez, Paula Jiménez-Fonseca, Eva Martínez de Castro, Manuel Sánchez-Cánovas, Laura Visa, Ana Custodio, Ana Fernández-Montes, Julia Peñas-Martínez, Patricia Morales del Burgo, Javier Gallego, Ginés Luengo-Gil, Vicente Vicente, Irene Martínez-Martínez, Alberto Carmona-Bayonas
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 148 (2022)
Advanced gastric cancer is one of the most thrombogenic neoplasms. However, genetic mechanisms underlying this complication remain obscure, and the molecular and histological heterogeneity of this neoplasm hinder the identification of thrombotic biom
Externí odkaz:
https://doaj.org/article/ab68f8a34c5045b4be7c73162f94c5cd
Autor:
Julia Peñas-Martínez, Ginés Luengo-Gil, Salvador Espín, Nataliya Bohdan, Carmen Ortega-Sabater, Maria Carmen Ródenas, David Zaragoza-Huesca, María José López-Andreo, Carme Plasencia, Vicente Vicente, Alberto Carmona-Bayonas, Irene Martínez-Martínez
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 523 (2021)
Antithrombin, the main physiological inhibitor of the coagulation cascade, exerts anti-tumor effects on glioblastoma multiforme cells. Antithrombin has different conformations: native, heparin-activated, prelatent, latent, and cleaved. The prelatent
Externí odkaz:
https://doaj.org/article/c64fa4755e314cc7b1a0e322be8cebb6
Autor:
David Zaragoza-Huesca, Andrés Nieto-Olivares, Francisco García-Molina, Guillermo Ricote, Sofía Montenegro, Manuel Sánchez-Cánovas, Pedro Garrido-Rodríguez, Julia Peñas-Martínez, Vicente Vicente, Francisco Martínez, María Luisa-Lozano, Alberto Carmona-Bayonas, Irene Martínez-Martínez
Publikováno v:
Cancers; Volume 14; Issue 13; Pages: 3106
BackgroundHepsin is a type II transmembrane serine protease whose functions include degradation of the extracellular matrix and activation of factor VII. In many tumors, hepsin dysregulation leads to tumor invasion by proteolysis of pericellular comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c322f9066f900fa33718ea4e32bb91
https://doi.org/10.1101/2022.05.14.22275077
https://doi.org/10.1101/2022.05.14.22275077
Autor:
David Zaragoza-Huesca, Carlos Martínez-Cortés, Antonio Jesús Banegas-Luna, Alfonso Pérez-Garrido, Josefina María Vegara-Meseguer, Julia Peñas-Martínez, Maria Carmen Rodenas, Salvador Espín, Horacio Pérez-Sánchez, Irene Martínez-Martínez
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2796
The endogenous protease furin is a key protein in many different diseases, such as cancer and infections. For this reason, a wide range of studies has focused on targeting furin from a therapeutic point of view. Our main objective consisted of identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2a52afb0e71ca812d6692d6b0a8d22
https://pubmed.ncbi.nlm.nih.gov/35269938
https://pubmed.ncbi.nlm.nih.gov/35269938
Autor:
Carme Plasencia, Carmen Ortega-Sabater, David Zaragoza-Huesca, Julia Peñas-Martínez, Irene Martínez-Martínez, Maria Jose Lopez-Andreo, Ginés Luengo-Gil, Nataliya Bohdan, Vicente Vicente, Salvador Espín, Alberto Carmona-Bayonas, M.C. Rodenas
Publikováno v:
Biomedicines
Volume 9
Issue 5
Biomedicines, Vol 9, Iss 523, p 523 (2021)
Volume 9
Issue 5
Biomedicines, Vol 9, Iss 523, p 523 (2021)
Antithrombin, the main physiological inhibitor of the coagulation cascade, exerts anti-tumor effects on glioblastoma multiforme cells. Antithrombin has different conformations: native, heparin-activated, prelatent, latent, and cleaved. The prelatent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9f569305a11c835ac558b1e21f7e28