Zobrazeno 1 - 10
of 86
pro vyhledávání: '"David Z. Chang"'
Autor:
Marwan Fakih, Kanwal Pratap Singh Raghav, David Z. Chang, Tim Larson, Allen L. Cohn, Timothy K. Huyck, David Cosgrove, Joseph A. Fiorillo, Rachel Tam, David D'Adamo, Neelesh Sharma, Barbara J. Brennan, Ying A. Wang, Sabine Coppieters, Hong Zebger-Gong, Anke Weispfenning, Henrik Seidel, Bart A. Ploeger, Udo Mueller, Carolina Soares Viana de Oliveira, Andrew Scott Paulson
Publikováno v:
EClinicalMedicine, Vol 58, Iss , Pp 101917- (2023)
Summary: Background: Anti-programmed cell death protein 1 antibodies plus multikinase inhibitors have shown encouraging activity in several tumour types, including colorectal cancer. This study assessed regorafenib plus nivolumab in patients with mic
Externí odkaz:
https://doaj.org/article/607bb200b67a4b90be60f4ef3e49d300
Autor:
John H. Strickler, Christel N. Rushing, Donna Niedzwiecki, Abigail McLeod, Ivy Altomare, Hope E. Uronis, S. David Hsu, S. Yousuf Zafar, Michael A. Morse, David Z. Chang, James L. Wells, Kimberly L. Blackwell, P. Kelly Marcom, Christy Arrowood, Emily Bolch, Sherri Haley, Fatima A. Rangwala, Ace J. Hatch, Andrew B. Nixon, Herbert I. Hurwitz
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Patients with chemotherapy refractory metastatic colorectal cancer (CRC) have a poor prognosis and limited therapeutic options. In this phase Ib/II clinical trial, we established the maximum tolerated dose (MTD) and recommended ph
Externí odkaz:
https://doaj.org/article/cee4dcf4fc8d4276878e7ac77b99ef23
Autor:
Lauren L. Siewertsz van Reesema, Vasilena Zheleva, Janet S. Winston, Rick J. Jansen, Carolyn F. O’Connor, Andrew J. Isbell, Minglei Bian, Rui Qin, Patricia T. Bassett, Virginia J. Hinson, Kimberly A. Dorsch, Brad W. Kirby, Robert E. Van Sciver, Angela M. Tang-Tan, Elizabeth A. Harden, David Z. Chang, Cynthia A. Allen, Roger R. Perry, Richard A. Hoefer, Amy H. Tang
Publikováno v:
EBioMedicine, Vol 11, Iss C, Pp 183-198 (2016)
Background: Metastatic breast cancer exhibits diverse and rapidly evolving intra- and inter-tumor heterogeneity. Patients with similar clinical presentations often display distinct tumor responses to standard of care (SOC) therapies. Genome landscape
Externí odkaz:
https://doaj.org/article/65a73692ab8c408685ec6d1a14fec41e
Autor:
Gagan K. Gupta, Amber L. Collier, Dasom Lee, Richard A. Hoefer, Vasilena Zheleva, Lauren L. Siewertsz van Reesema, Angela M. Tang-Tan, Mary L. Guye, David Z. Chang, Janet S. Winston, Billur Samli, Rick J. Jansen, Emanuel F. Petricoin, Matthew P. Goetz, Harry D. Bear, Amy H. Tang
Publikováno v:
Cancers, Vol 12, Iss 9, p 2392 (2020)
Triple-negative breast cancer (TNBC), characterized by the absence or low expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor (HER2), is the most aggressive subtype of breast cancer. TNBC accou
Externí odkaz:
https://doaj.org/article/01aa53826907478b914310880ae04d1e
Autor:
Feng Wang-Johanning, Gary L. Johanning, Donghui Li, David Z. Chang, JianJun Shen, Yue Lu, Kevin Lin, Raghavender Chivukula, Jia Li, Kiera Rycaj, Bingnan Yin, Laszlo Radvanyi, Ming Li
Supplementary Table 1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fe483179a4f64265f04891f80c47be
https://doi.org/10.1158/1078-0432.22467171.v1
https://doi.org/10.1158/1078-0432.22467171.v1
Autor:
Patrick Hwu, Craig D. Logsdon, Yong-jun Liu, James L. Abbruzzese, Yan Liu, Defeng Deng, Huamin Wang, Baoan Ji, Ying Ma, David Z. Chang
PDF file - 78.8KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e59e8db8a8994fbc80692a098638980
https://doi.org/10.1158/1078-0432.22443878.v1
https://doi.org/10.1158/1078-0432.22443878.v1
Autor:
David Z. Chang, James L. Abbruzzese, Constantin G. Ioannides, Yufeng Li, Satoshi Ishiyama, Naotake Tsuda
Supplementary Figures 1-3, Tables 1-3 from Synthetic MicroRNA Designed to Target Glioma-Associated Antigen 1 Transcription Factor Inhibits Division and Induces Late Apoptosis in Pancreatic Tumor Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca0634baa00db3d8025f6c3db4af47e
https://doi.org/10.1158/1078-0432.22441492.v1
https://doi.org/10.1158/1078-0432.22441492.v1
Autor:
Feng Wang-Johanning, Gary L. Johanning, Donghui Li, David Z. Chang, JianJun Shen, Yue Lu, Kevin Lin, Raghavender Chivukula, Jia Li, Kiera Rycaj, Bingnan Yin, Laszlo Radvanyi, Ming Li
Purpose: We investigated the role of the human endogenous retrovirus type K (HERV-K) envelope (env) gene in pancreatic cancer.Experimental Design: shRNA was employed to knockdown (KD) the expression of HERV-K in pancreatic cancer cells.Results: HERV-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0519aba8b1f0321ffd7cb8d8b9c588c5
https://doi.org/10.1158/1078-0432.c.6526557
https://doi.org/10.1158/1078-0432.c.6526557
Autor:
David Z. Chang, James L. Abbruzzese, Constantin G. Ioannides, Yufeng Li, Satoshi Ishiyama, Naotake Tsuda
Purpose: To determine whether the synthetic microRNAs (miRNA) could effectively target tumor cells we designed several miRNA complementary to glioma-associated antigen-1 (Gli-1) mRNA and investigated their ability to inhibit tumor cell proliferation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a585d85f7f1e4499c192c0bf025ccae
https://doi.org/10.1158/1078-0432.c.6518545.v1
https://doi.org/10.1158/1078-0432.c.6518545.v1
Autor:
Keping Xie, Suyun Huang, David Z. Chang, James C. Yao, Daoyan Wei, Xiangdong Le, Jun Zhang, Qiang Li, Liwei Wang, Yong Gao, Zhiliang Jia
Mithramycin (MIT) and tolfenamic acid (TA) inhibit the activity of the transcription factor Sp1. In the present study, we investigated whether pancreatic cancer treatment with a combination of these compounds has a synergistic effect on Sp1 activity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17e1d759640f2223e02b5109c49d441c
https://doi.org/10.1158/0008-5472.c.6500708
https://doi.org/10.1158/0008-5472.c.6500708