Zobrazeno 1 - 10
of 17
pro vyhledávání: '"David Yin-wei Lin"'
Autor:
David Yin-wei Lin, Lauren E Kueffer, Puneet Juneja, Thomas E Wales, John R Engen, Amy H Andreotti
Publikováno v:
eLife, Vol 12 (2024)
Full-length Bruton’s tyrosine kinase (BTK) has been refractory to structural analysis. The nearest full-length structure of BTK to date consists of the autoinhibited SH3–SH2–kinase core. Precisely how the BTK N-terminal domains (the Pleckstrin
Externí odkaz:
https://doaj.org/article/6893fa79a72b4e8bbfd35d28b126c009
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 2 (2011)
Ubiquitination is a post-translational modification in which one or more 76 amino acid polypeptide ubiquitin molecules are covalently linked to the lysine residues of target proteins. Ubiquitination is the main pathway for protein degradation that go
Externí odkaz:
https://doaj.org/article/b271765e581445349e70fdeddf82e625
Autor:
E. Poleze, E. R. de Oliveira, A. Aldaz, David Yin-wei Lin, C. A. da Silva, Marco Aurélio Callegari, C. Pazinato Dias, C.K. Mah, K. Lais L. de Souza, Jim Allison, J.V. Peloso
Publikováno v:
Research in Veterinary Science. 136:127-137
Reproductive cycling in fattening gilts can be associated with undesirable effects, such as estrus-related aggressive behavior, reduced feed intake and, in production systems where gilts are co-housed with entire males, unwanted pregnancy. Immunizati
Publikováno v:
Biochem Soc Trans
The SRC, Abelson murine leukemia viral oncogene homolog 1, TEC and C-terminal SRC Kinase families of non-receptor tyrosine kinases (collectively the Src module kinases) mediate an array of cellular signaling processes and are therapeutic targets in m
Publikováno v:
Polymer. 118
Electrospinning has become a widely-used method for fabricating polymer nanofibers for various applications including filtration, drug delivery, and tissue engineering. Due to the high extensional forces during the electrospinning process, and the ra
Autor:
Jyotsna Pandya, Timothy B. Stockwell, Rodion Gorchakov, Scott C. Weaver, Rebecca A. Halpin, Naomi L. Forrester, Grace Leal, Ravi Jain, Kumar Hari, David E. Wentworth, David Yin-wei Lin, Rubing Chen, Joel O. Wertheim, M. D. Smith, Albert J. Auguste, Jose G. Estrada-Franco, Vivian G. Dugan, A. Paige Adams, Sergei L. Kosakovsky Pond, Suman R. Das
Publikováno v:
PLoS neglected tropical diseases, vol 11, iss 8
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 11, Iss 8, p e0005693 (2017)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 11, Iss 8, p e0005693 (2017)
Venezuelan equine encephalitis (VEE) complex alphaviruses are important re-emerging arboviruses that cause life-threatening disease in equids during epizootics as well as spillover human infections. We conducted a comprehensive analysis of VEE comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c78afa6ca651152b476fecca86cf5c
https://escholarship.org/uc/item/52b467cf
https://escholarship.org/uc/item/52b467cf
Autor:
David Yin-wei Lin, Ravi Jain, Vinita Puri, Suman R. Das, Scott C. Weaver, Rubing Chen, Reed S. Shabman, Nadia Fedorova, Juan D Rodas, Kumar Hari
Since the India and Indian Ocean outbreaks of 2005 and 2006, the global distribution of chikungunya virus (CHIKV) and the locations of epidemics have dramatically shifted. First, the Indian Ocean lineage (IOL) caused sustained epidemics in India and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f465779dc2d7a0aed0355e8d3a854f67
https://europepmc.org/articles/PMC5110187/
https://europepmc.org/articles/PMC5110187/
Publikováno v:
Proceedings of the National Academy of Sciences. 109:1925-1930
In eukaryotes, ubiquitination is an important posttranslational process achieved through a cascade of ubiquitin-activating (E1), conjugating (E2), and ligase (E3) enzymes. Many pathogenic bacteria deliver virulence factors into the host cell that fun
Publikováno v:
The Journal of Biological Chemistry
Many microbial pathogens deliver effector proteins via the type III secretion system into infected host cells. Elucidating the function of these effectors is essential for our understanding of pathogenesis. Here, we describe biochemical and structura
Publikováno v:
Journal of Virology. 80:7706-7713
The possibility of the release of smallpox virus into a predominantly nonimmunized population highlights the importance of understanding poxvirus biology. Poxviruses encode a conserved pathway that is required to oxidize disulfide bonds in nascent vi