Zobrazeno 1 - 7
of 7
pro vyhledávání: '"David Yang-Wei Fann"'
Autor:
Thiruma V Arumugam, Asfa Alli-Shaik, Elisa A Liehn, Sharmelee Selvaraji, Luting Poh, Vismitha Rajeev, Yoonsuk Cho, Yongeun Cho, Jongho Kim, Joonki Kim, Hannah LF Swa, David Tan Zhi Hao, Chutima Rattanasopa, David Yang-Wei Fann, David Castano Mayan, Gavin Yong-Quan Ng, Sang-Ha Baik, Karthik Mallilankaraman, Mathias Gelderblom, Grant R Drummond, Christopher G Sobey, Brian K Kennedy, Roshni R Singaraja, Mark P Mattson, Dong-Gyu Jo, Jayantha Gunaratne
Publikováno v:
eLife, Vol 12 (2023)
Intermittent fasting (IF) has been shown to reduce cardiovascular risk factors in both animals and humans, and can protect the heart against ischemic injury in models of myocardial infarction. However, the underlying molecular mechanisms behind these
Externí odkaz:
https://doaj.org/article/77c3c141082e4538bda530d5762d0666
Publikováno v:
Brain and Behavior, Vol 10, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Intermittent fasting (IF) has been suggested to have neuroprotective effects through the activation of multiple signaling pathways. Rodents fasted intermittently exhibit enhanced hippocampal neurogenesis and long‐term potentia
Externí odkaz:
https://doaj.org/article/1c37724dc7e343d58a4df6ea41ea6dce
Autor:
Gavin Yong-Quan Ng, Sung-Wook Kang, Joonki Kim, Asfa Alli-Shaik, Sang-Ha Baik, Dong-Gyu Jo, M. Prakash Hande, Christopher G. Sobey, Jayantha Gunaratne, David Yang-Wei Fann, Thiruma V. Arumugam
Publikováno v:
Dose-Response, Vol 17 (2019)
Scope: Intermittent fasting (IF) has been extensively reported to promote improved energy homeostasis and metabolic switching. While IF may be a plausible strategy to ameliorate the epidemiological burden of disease in many societies, our understandi
Externí odkaz:
https://doaj.org/article/2ec6ee19ab90465aa6887e5205e538fc
Autor:
Gavin Yong-Quan Ng, Yun-An Lim, Christopher G. Sobey, Thameem Dheen, David Yang-Wei Fann, Thiruma V. Arumugam
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 11 (2018)
Despite extensive research, treatments for clinical stroke are still limited only to the administration of tissue plasminogen activator and the recent introduction of mechanical thrombectomy, which can be used in only a limited proportion of patients
Externí odkaz:
https://doaj.org/article/1802398ac92d43c3b7d7fa506bea0a1a
Autor:
Yi-Lin Cheng, Jong-Sung Park, Silvia Manzanero, Yuri Choi, Sang-Ha Baik, Eitan Okun, Mathias Gelderblom, David Yang-Wei Fann, Tim Magnus, Bradley S. Launikonis, Mark P. Mattson, Christopher G. Sobey, Dong-Gyu Jo, Thiruma V. Arumugam
Publikováno v:
Neurobiology of Disease, Vol 62, Iss , Pp 286-295 (2014)
Recent findings suggest that Notch-1 signaling contributes to neuronal death in ischemic stroke, but the underlying mechanisms are unknown. Hypoxia inducible factor-1α (HIF-1α), a global regulator of cellular responses to hypoxia, can interact with
Externí odkaz:
https://doaj.org/article/35c6cf2c2f4247e9ab8381698e73d964
Autor:
Gavin Yong-Quan Ng, Dominic Paul Lee Kok Sheng, Han-Gyu Bae, Sung Wook Kang, David Yang-Wei Fann, Jinsu Park, Joonki Kim, Asfa Alli-Shaik, Jeongmi Lee, Eunae Kim, Sunyoung Park, Jeung-Whan Han, Vardan Karamyan, Eitan Okun, Thameem Dheen, Manoor Prakash Hande, Raghu Vemuganti, Karthik Mallilankaraman, Lina H. K. Lim, Brian K. Kennedy, Grant R. Drummond, Christopher G. Sobey, Jayantha Gunaratne, Mark P. Mattson, Roger Sik-Yin Foo, Dong-Gyu Jo, Thiruma V. Arumugam
Publikováno v:
GeroScience
Intermittent fasting (IF) remains the most effective intervention to achieve robust anti-aging effects and attenuation of age-related diseases in various species. Epigenetic modifications mediate the biological effects of several environmental factor
Autor:
Sang-Ha, Baik, Mitchell, Fane, Joon Hyung, Park, Yi-Lin, Cheng, David, Yang-Wei Fann, Ui Jeong, Yun, Yuri, Choi, Jong-Sung, Park, Bing Han, Chai, Jin Su, Park, Seung Hyun, Back, Jae In, Jeong, Ye Jin, Jang, Gahee, Bahn, Joo-Yong, Lee, Yu-I, Li, Christopher G, Sobey, Takafumi, Uchida, Jae Hyung, Park, Hong Tae, Kim, Sung-Chun, Tang, Thiruma V, Arumugam, Dong-Gyu, Jo
Publikováno v:
Annals of neurology. 77(3)
Stroke is a leading cause of mortality and disability. The peptidyl-prolyl cis/trans isomerase Pin1 regulates factors involved in cell growth. Recent evidence has shown that Pin1 plays a major role in apoptosis. However, the role of Pin1 in ischemic