Zobrazeno 1 - 10
of 63
pro vyhledávání: '"David Y Oh"'
Autor:
Li Zhang, Lawrence Fong, Brittany Davidson, David Y Oh, Frances Fan, Alexander Cheung, Hai Yang, Jun Yan He, Yang-Joon Kim, Elvira Mennillo, Iulia Rusu, Jared Bain, Arjun A Rao, Christopher Andersen, Karen Law, Jessica Tsui, Alan Shen, Divyashree Kushnoor, Yimin Shi, Alexis J Combes, Angela O Pisco, Michael G Kattah
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Colitis caused by checkpoint inhibitors (CPI) is frequent and is treated with empiric steroids, but CPI colitis mechanisms in steroid-experienced or refractory disease are unclear.Methods Using colon biopsies and blood from predominantly s
Externí odkaz:
https://doaj.org/article/b3f6c1938ee54e789586fef9baa1e152
Autor:
Li Zhang, Lawrence Fong, David Y Oh, Eliezer Van Allen, Felix Y Feng, Anthony Wong, Eric J Small, Terence W Friedlander, Alec Starzinski, Zenghua Fan, Tony Li, Hewitt Chang, Marissa Gin, Katsuto Shinohara, Hao Nguyen, Caleb Hwang, Christopher De Leon, Rahul R Aggarwal
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/0340aac11ac1489581066e7c00216656
Autor:
Li Zhang, Divya Natesan, Lawrence Fong, Emily Chan, David Y Oh, Son Ho, Ivan de Kouchkovsky, Errol J Philip, Francis Wright, Daniel M Kim, Daniel Kwon, Hansen Ho, Sima P Porten, Anthony C Wong, Arpita Desai, Franklin W Huang, Jonathan Chou, Raj S Pruthi, Eric J Small, Terence W Friedlander, Vadim S Koshkin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Background Immune checkpoint inhibitors (ICI) can achieve durable responses in a subset of patients with locally advanced or metastatic urothelial carcinoma (aUC). The use of tumor genomic profiling in clinical practice may help suggest biomarkers to
Externí odkaz:
https://doaj.org/article/daffc1a2d771420089913bf03e6aaad2
Autor:
Ning Zhao, Conner Bardine, André Luiz Lourenço, Yung-hua Wang, Yangjie Huang, Simon J. Cleary, David M. Wilson, David Y. Oh, Lawrence Fong, Mark R. Looney, Michael J. Evans, Charles S. Craik
Publikováno v:
ACS Central Science, Vol 7, Iss 10, Pp 1638-1649 (2021)
Externí odkaz:
https://doaj.org/article/855612b3a40e4f52a10ffc43856da1af
Autor:
Katsunobu Hagihara, Stephen Chan, Li Zhang, David Y. Oh, Xiao X. Wei, Jeffry Simko, Lawrence Fong
Publikováno v:
OncoImmunology, Vol 8, Iss 1 (2019)
Sipuleucel-T is the only FDA-approved immunotherapy for metastatic castration-resistant prostate cancer. The mechanism by which this treatment improves survival is not fully understood. We have previously shown that this treatment can induce the recr
Externí odkaz:
https://doaj.org/article/03b05b99d7c1490795f7775d00392bf0
Autor:
Lawrence Fong, Nadeem A. Sheikh, David Y. Oh, Tao He, Jason Cham, Hai Yang, Harini Kandadi, Li Zhang
Supplementary Fig. 4: (A-D) BCR convergent groups converge to shared amino acid sequences. (A-B) Phylogenetic trees across all repertories of a representative naive patient (A) and of a representative treated patient (B). For each patient, social net
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9d81c1fee6dcaf99dcbba592fbd381
https://doi.org/10.1158/2326-6066.22543507
https://doi.org/10.1158/2326-6066.22543507
Autor:
Lawrence Fong, Nadeem A. Sheikh, David Y. Oh, Tao He, Jason Cham, Hai Yang, Harini Kandadi, Li Zhang
Supplementary Fig. 2A: Changes in rank of the top 100 BCR clones at week 2 for a representative naïve patient are shown. The top 100 clonotypes at week 2 were identified based on their abundances at week 2. The rank of those clones at other timepoin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ef8d41f971c71cba7e91043379a971
https://doi.org/10.1158/2326-6066.22543513.v1
https://doi.org/10.1158/2326-6066.22543513.v1
Autor:
Lawrence Fong, Nadeem A. Sheikh, David Y. Oh, Tao He, Jason Cham, Hai Yang, Harini Kandadi, Li Zhang
Sipuleucel-T is an autologous cellular immunotherapy, administered as three infusions, for metastatic castration-resistant prostate cancer (mCRPC). Sipuleucel-T induces T- and B-cell responses to prostatic acid phosphatase (PAP), correlating to impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4e38aea97137bc0a8fe4bf729cc932
https://doi.org/10.1158/2326-6066.c.6550294.v1
https://doi.org/10.1158/2326-6066.c.6550294.v1
Autor:
Lawrence Fong, Nadeem A. Sheikh, David Y. Oh, Tao He, Jason Cham, Hai Yang, Harini Kandadi, Li Zhang
Supplementary Fig. 5: Sensitivity analysis of social network analysis of the representative sipuleucel-T treated patient. (A) Density plot of the clone frequency for all clones of the treated patient (red) and density plot of the clone frequency for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758816d491ee1bee42e0426c1aa44d8a
https://doi.org/10.1158/2326-6066.22543504.v1
https://doi.org/10.1158/2326-6066.22543504.v1
Autor:
Lawrence Fong, Nadeem A. Sheikh, David Y. Oh, Tao He, Jason Cham, Hai Yang, Harini Kandadi, Li Zhang
Selected convergent groups. (A) Illustration of the groups that are persistently present across all time points for the treated patient. (B) Illustration of the groups induced in the treated patient. (C) Illustration of the induced groups in the naiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15474e8fd0392e08246de8c71ae25910
https://doi.org/10.1158/2326-6066.22543510
https://doi.org/10.1158/2326-6066.22543510