Zobrazeno 1 - 5
of 5
pro vyhledávání: '"David Y Nie"'
Autor:
Ronan P. Hanley, David Y. Nie, John R. Tabor, Fengling Li, Amin Sobh, Chenxi Xu, Natalie K. Barker, David Dilworth, Taraneh Hajian, Elisa Gibson, Magdalena M. Szewczyk, Peter J. Brown, Dalia Barsyte-Lovejoy, Laura E. Herring, Gang Greg Wang, Jonathan D. Licht, Masoud Vedadi, Cheryl H. Arrowsmith, Lindsey I. James
Publikováno v:
Journal of the American Chemical Society. 145:8176-8188
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95bc98e1fc4dc9f993866f26284bf64e
https://doi.org/10.1021/jacs.3c01421
https://doi.org/10.1021/jacs.3c01421
Autor:
Victoria, Vu, Magdalena M, Szewczyk, David Y, Nie, Cheryl H, Arrowsmith, Dalia, Barsyte-Lovejoy
Publikováno v:
Annual Review of Biochemistry. 91:61-87
Small molecule chemical probes are valuable tools for interrogating protein biological functions and relevance as a therapeutic target. Rigorous validation of chemical probe parameters such as cellular potency and selectivity is critical to unequivoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9d258b06c28692f7e375086129dc9d
https://doi.org/10.1146/annurev-biochem-032620-105344
https://doi.org/10.1146/annurev-biochem-032620-105344
Autor:
Marcus A. Cheek, Aiping Dong, Renato Ferreira de Freitas, Dalia Barsyte-Lovejoy, Aliakbar Khalili Yazdi, Jinrong Min, Fengling Li, Victoria Vu, Albina Bolotokova, Lindsey I. James, Jack Greenblatt, Naimee Mehta, Irina K. Popova, David Dilworth, Ming Lei, Raquel Arminda Carvalho Machado, Ronan P Hanley, David Y Nie, Matthieu Schapira, Mengqi Zhou, Elisa Gibson, Cheryl H. Arrowsmith, Michael-Christopher Keogh, Suzanne Ackloo, Matthew R. Marunde, Mona Alqazzaz, Dmitri Kireev, Nathan W. Hall, Peter Brown, Abdellah Allali-Hassani, Sina Kazemzadeh, Edyta Marcon, Tigran M. Abramyan, Dominic D G Owens, Yanli Liu, Magdalena M. Szewczyk, Matthew J. Meiners, Irene Chau, Su Qin, Masoud Vedadi
Publikováno v:
Nat Chem Biol
Nuclear receptor-binding SET domain-containing 2 (NSD2) is the primary enzyme responsible for the dimethylation of lysine 36 of histone 3 (H3K36), a mark associated with active gene transcription and intergenic DNA methylation. In addition to a methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29b52d0f1e30e6d3bd73de3c2a5989b
https://doi.org/10.1038/s41589-021-00898-0
https://doi.org/10.1038/s41589-021-00898-0
Autor:
Cheryl H. Arrowsmith, Jocelyn Chen, Nergiz Artun, Jian Jin, Magdalena M. Szewczyk, Jing Liu, Wail Ba alawi, Qin Wu, David W. Cescon, Felipe Ciamponi, Geneviève Deblois, Daniel D. De Carvalho, Lan Xin Zhang, Jennifer Cruickshank, Parinaz Mehdipour, Katlin Maussirer, Dalia Barsyte-Lovejoy, Panagiotis Prinos, Sajid A. Marhon, Benjamin Haibe-Kains, Shili Duan, Wenjun Chen, Mathieu Lupien, David Y Nie, YiShuai Ji, Yudao Shen, Jillian Haight
Triple negative breast cancer (TNBC) is the most aggressive breast cancer subtype with the worst prognosis and few effective therapies. Here, we undertook a screen of epigenetic chemical probes to systematically uncover the epigenetic regulators crit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01de5bbaa1f1a3526246a5ddb617665
https://ora.ox.ac.uk/objects/uuid:4e028a21-2cb6-4b3d-a99d-fcdce5a080d9
https://ora.ox.ac.uk/objects/uuid:4e028a21-2cb6-4b3d-a99d-fcdce5a080d9
Autor:
Qin Wu, David Y. Nie, Wail Ba-alawi, YiShuai Ji, ZiWen Zhang, Jennifer Cruickshank, Jillian Haight, Felipe E. Ciamponi, Jocelyn Chen, Shili Duan, Yudao Shen, Jing Liu, Sajid A. Marhon, Parinaz Mehdipour, Magdalena M. Szewczyk, Nergiz Dogan-Artun, WenJun Chen, Lan Xin Zhang, Genevieve Deblois, Panagiotis Prinos, Katlin B. Massirer, Dalia Barsyte-Lovejoy, Jian Jin, Daniel D. De Carvalho, Benjamin Haibe-Kains, XiaoJia Wang, David W. Cescon, Mathieu Lupien, Cheryl H. Arrowsmith
Publikováno v:
Nature chemical biology. 18(8)
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype with the worst prognosis and few effective therapies. Here we identified MS023, an inhibitor of type I protein arginine methyltransferases (PRMTs), which has antitumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e053a6a43b2d55b8a9ab0d5b48f865fb
https://pubmed.ncbi.nlm.nih.gov/35578033
https://pubmed.ncbi.nlm.nih.gov/35578033