Zobrazeno 1 - 4
of 4
pro vyhledávání: '"David Y C Cheung"'
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29099 (2011)
Senescence, the state of permanent cell cycle arrest, has been associated with endothelial cell dysfunction and atherosclerosis. The cyclin dependent kinase inhibitors p21(CIP1/WAF1) and p16(INK4a) govern the G(1)/S cell cycle checkpoint and are esse
Externí odkaz:
https://doaj.org/article/e4d21c7a6f9f467896251a619d467d93
Autor:
Cameron R. Eekhoudt, Tessa Bortoluzzi, Sonu S. Varghese, David Y. C. Cheung, Simon Christie, Skyler Eastman, Ishika Mittal, J. Alejandro Austria, Harold M. Aukema, Amir Ravandi, James Thliveris, Pawan K. Singal, Davinder S. Jassal
Publikováno v:
Current Oncology, Vol 29, Iss 5, Pp 2941-2953 (2022)
Background: Two anti-cancer agents, doxorubicin (DOX) and trastuzumab (TRZ), are commonly used in the management of breast cancer in women. Despite their efficacy in reducing the morbidity and mortality of individuals with breast cancer, the use of t
Externí odkaz:
https://doaj.org/article/c9e8e996f3834871b877bd545c967462
Autor:
Raghu S Nagalingam, Sikta Chattopadhyaya, Danah S Al-Hattab, David Y C Cheung, Leah Y Schwartz, Sayantan Jana, Nina Aroutiounova, D Allison Ledingham, Teri L Moffatt, Natalie M Landry, Rushita A Bagchi, Ian M C Dixon, Jeffrey T Wigle, Gavin Y Oudit, Zamaneh Kassiri, Davinder S Jassal, Michael P Czubryt
Publikováno v:
European Heart Journal. 43:4739-4750
Aims In response to pro-fibrotic signals, scleraxis regulates cardiac fibroblast activation in vitro via transcriptional control of key fibrosis genes such as collagen and fibronectin; however, its role in vivo is unknown. The present study assessed
Autor:
Navid, Koleini, Barbara E, Nickel, Raghu S, Nagalingam, Natalie M, Landry, Robert R, Fandrich, David Y C, Cheung, Ian M, Dixon, Michael P, Czubryt, Davinder S, Jassal, Peter A, Cattini, Elissavet, Kardami
Publikováno v:
Cell and tissue research. 385(3)
Fibroblast growth factor 2 (FGF2), produced as high (Hi-) and low (Lo-) molecular weight isoforms, is implicated in cardiac response to injury. The role of endogenous FGF2 isoforms during chronic stress is not well defined. We investigated the effect