Zobrazeno 1 - 10
of 40
pro vyhledávání: '"David Y B, Deng"'
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-17 (2023)
Abstract Activation of endogenous neural stem cells (NSCs) is greatly significant for the adult neurogenesis; however, it is extremely limited in the spinal cord after injury. Recent evidence suggests that accumulation of protein aggregates impairs t
Externí odkaz:
https://doaj.org/article/32e189cd225a4e39b3b62d2601060c08
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundExcessive neutrophil extracellular traps (NETs) is involved in the progression of acute pancreatitis (AP) but the mechanisms controlling NETs formation in AP are not fully understood. Therefore, our study sought to investigate the mechanism
Externí odkaz:
https://doaj.org/article/185226daf3cd4447aeffbe254b10a4e7
Autor:
Changlin Zhang, Wei Liao, Weizhao Li, Mengxiong Li, Xiaoyu Xu, Haohui Sun, Yaohua Xue, Lixiang Liu, Jiehong Qiu, Chi Zhang, Xunzhi Zhang, Juntong Ye, Jingran Du, David Y. B. Deng, Wuguo Deng, Tian Li
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Background: With an increasing number of patients experiencing infertility due to chronic salpingitis after Chlamydia trachomatis (CT) infection, there is an unmet need for tissue repair or regeneration therapies. Treatment with human umbilical cord
Externí odkaz:
https://doaj.org/article/b44836939ff74bba9d5e3f98b32a7362
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-13 (2022)
Abstract Background The effects of bone marrow mesenchymal stem cells (BMSCs) during the treatment of cartilage damage have been proven to be attributed to paracrine mechanisms, particularly the effect of exosomes. Exosomes from different batches are
Externí odkaz:
https://doaj.org/article/340ef1e675854fba92a1d46d9849378b
Autor:
Ming Shi, Qi Xu, Lu Ding, Yu Xia, Changlin Zhang, Haibin Lai, Changxuan Liu, David Y. B. Deng
Publikováno v:
ACS biomaterials scienceengineering. 8(12)
The disadvantages of cell-adaptive microenvironments and cellular diffusion out of the lesion have limited hydrogel-based scaffold transplantation treatment for neural connectivity, leading to permanent neurological disability from spinal cord injury
Publikováno v:
Stem Cells International, Vol 2017 (2017)
The use of human telomerase reverse transcriptase-immortalized bone marrow mesenchymal stromal cells (hTERT-BMSCs) as vehicles to deliver antinociceptive galanin (GAL) molecules into pain-processing centers represents a novel cell therapy strategy fo
Externí odkaz:
https://doaj.org/article/c7bd5b81d9bf48688da25e9436dc5751
Autor:
Xuhong Mao, Juzhen Yi, Lingli Long, Liqun Yang, David Y. B. Deng, Juncheng Shen, Kunhua Lin, Li-Ming Zhang, Lin Yin
Publikováno v:
Food & Function. 12:8522-8534
Tea polysaccharides exhibit multiple important bioactivities, but very few of them can be absorbed through the small intestine. To enhance the absorption efficacy of tea polysaccharides, a cationic vitamin B12-conjugated glycogen derivative bearing t
Publikováno v:
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
Spinal cord injury (SCI) is a complex pathological process. Based on the encouraging results of preclinical experiments, some stem cell therapies have been translated into clinical practice. Mesenchymal stem cells (MSCs) have become one of the most i
Autor:
Zunfu Ke, Li-Ming Zhang, Xin Yuan, Jiahao Luo, Minghua Lai, Xuhong Mao, Lingli Long, Liqun Yang, David Y. B. Deng
Publikováno v:
International Journal of Nanomedicine. 14:7743-7758
Purpose Peptide drugs have been used in therapy various diseases. However, the poor bioavailability of peptide drugs for oral administration has limited their clinical applications, on account of the acidic environment and digestive enzymes inside th
Autor:
Kai Zhu, Yong Wan, Xiang Li, Xiaoyang Zhao, Qingui Chen, Zhiming Peng, David Y. B. Deng, Mengxia Fu, Lingli Long
Publikováno v:
Journal of Neurochemistry. 150:709-722
Neural stem cells (NSCs) transplantation represents a promising strategy for the repair of injured neurons, since NSCs not only produce multiple neurotrophic growth factors but also differentiate into mature cells to replace damaged cells. Previous s