Výsledky vyhledávání - "David Wolfer"

Akademický článek

Loss of Nogo-A, encoded by the schizophrenia risk gene Rtn4, reduces mGlu3 expression and causes hyperexcitability in hippocampal CA3 circuits.

Autor: Stewart Berry, Oliver Weinmann, Ann-Kristina Fritz, Ruslan Rust, David Wolfer, Martin E Schwab, Urs Gerber, Jeanne Ster

Publikováno v: PLoS ONE, Vol 13, Iss 7, p e0200896 (2018)

Recent investigations of Nogo-A, a well characterized protein inhibitor of neurite outgrowth in the brain, have revealed additional functions including a role in neuropsychiatric disorders such as schizophrenia. Here we examined Nogo-A functions in m

Externí odkaz: https://doaj.org/article/d5dc40e5570b4ea19fe32fa070309203

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Using mice from different breeders fails to improve replicability of results

Autor: Hanno Würbel, Ivana Jaric, Bernhard Voelkl, Irmgard Amrein, David Wolfer, Janja Novak, Carlotta Detotto, Ulrike Weber-Stadlbauer, Urs Meyer, Francesca Manuella, Isabelle Mansuy

Theoretical and empirical evidence indicates that low external validity due to rigorous standardization of study populations is a cause of poor replicability in animal research. Here, we report a multi-laboratory study to test whether heterogenizatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4dea9d7adad9d278dc2410dceaf86bd8
https://doi.org/10.21203/rs.3.rs-2802374/v1