Zobrazeno 1 - 10 of 14 pro vyhledávání: '"David W.A. Bourne"'
1
Chemical Equilibria in Solutions of Bisulfite Salts
Autor: David W.A. Bourne, Takeru Higuchi, Ian H. Pitman
Publikováno v: Journal of Pharmaceutical Sciences. 63:865-868
The equilibrium between bisulfite ion and pyrosulfite ion in aqueous solutions of different ionic strengths was investigated spectrophotometrically. Values for the equilibrium constant at ionic strengths of 2.0, 0.9, 0.5, 0.1, and 0.01 M were found t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef63bfb83cc3e58eb85dc99004aae83
https://doi.org/10.1002/jps.2600630612
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2
MULTI-FORTE, a microcomputer program for modelling and simulation of pharmacokinetic data
Autor: David W.A. Bourne
Publikováno v: Computer Methods and Programs in Biomedicine. 23:277-281
MULTI-FORTE is an expanded version of the MULTI non-linear fitting programs written by Yamaoka et al. The functions of the three original programs (including Gauss-Newton and Simplex fitting algorithms) have been combined and translated into FORTRAN
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3170af0dd36829a2e67c0ddfe8a5e2f2
https://doi.org/10.1016/0169-2607(86)90062-3
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3
PHARMACOKINETICS OF ALCURONIUM IN ELDERLY PATIENTS UNDERGOING TOTAL HIP REPLACEMENT OR AORTIC RECONSTRUCTIVE SURGERY
Autor: P. C. Ho, E. J. Triggs, David W.A. Bourne, I.D. Stephens, A.M. Holloway
Publikováno v: British Journal of Anaesthesia. 56:465-471
The pharmacokinetic behaviour of alcuronium was studied in three patients undergoing resection of an aortic aneurysm, and in another two patients undergoing total hip replacement (group I). A control group of five elderly patients undergoing relative
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde2afc5e41a3af0c000fbd6e5185e4f
https://doi.org/10.1093/bja/56.5.465
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5
Physiological pharmacokinetic model for the distribution and elimination of tenoxicam
Autor: Kwang‐IL Kwon, David W.A. Bourne
Publikováno v: International Journal of Pharmaceutics. 37:219-226
A physiologically based pharmacokinetic model for tenoxicam distribution and excretion in the rat was developed. The drug concentrations in plasma and all the tissues except testis were simulated using flow-limited equations, while testis concentrati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41e91a9d17f55d2e0455716726fbfef5
https://doi.org/10.1016/0378-5173(87)90032-9
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6
Effect of probenecid on the pharmacokinetics of cefotaxime in sheep
Autor: L. J. Filippigh, David W.A. Bourne, G. R. Cao, V. H. Guerrini, P. B. English
Publikováno v: Journal of veterinary pharmacology and therapeutics. 8(1)
Guerrini, V.H., Filippich, L.J., English, P.B., Cao, G.R. &: Bourne, D.W.A. Effect of probenecid on the pharmacokinetics of cefotaxime in sheep. J. vet. Pharmacol. Therap. 8, 38–46. The effect of probenecid given by intravenous (i.v.), intramuscula
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05942eeed6c79171793f210245d2a0e4
https://pubmed.ncbi.nlm.nih.gov/3989899
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7
Disposition of sulfadimethoxine in swine: inclusion of protein binding factors in a pharmacokinetic model
Autor: R.F. Bevill, Gary D. Koritz, David W.A. Bourne, Lewis W. Dittert, G. Rudawsky, M. Hayashi, C. H. Huang
Publikováno v: Journal of pharmacokinetics and biopharmaceutics. 10(5)
Sulfadimethoxine was administered intravenously and orally to five swine. More than 75% of the dose was excreted into urine as the acetyl metabolite with 4-6% excreted unchanged. Plasma and urine data were not consistent when a linear pharmacokinetic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cdb6d580f7cedce54fc9be0974b9257
https://pubmed.ncbi.nlm.nih.gov/7166737
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9
Effect of caffeine on ceftriaxone disposition and plasma protein binding in the rat
Autor: Kwang I. Kwon, David W.A. Bourne
Publikováno v: Journal of pharmacokinetics and biopharmaceutics. 14(4)
Previous studies have shown that caffeine can affect drug kinetics by altering drug binding to plasma protein, drug absorption, or drug distribution. In this study, the effect of caffeine on the in vivo protein binding and the disposition of ceftriax
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102ad8981455b7a6c617aa44eb0f8f9a
https://pubmed.ncbi.nlm.nih.gov/3689487
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10
Pharmacokinetics of probenecid in sheep
Autor: Jenny Schneider, Lucio J. Filippich, G. R. Cao, V. H. Guerrini, David W.A. Bourne, P. B. English
Publikováno v: Journal of veterinary pharmacology and therapeutics. 8(2)
Six Merino ewes were given 1 g (27 g/kg) probenecid by the intravenous (i.v.), intramuscular (i.m.) and subcutaneous (s.c.) routes. After i.v. injection, the biological half-life was 1.55 h and apparent volume of distribution at the steady state (Vds
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b0893572170e08b0a6970727f6d1c4
https://pubmed.ncbi.nlm.nih.gov/4020944
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