Zobrazeno 1 - 10
of 24
pro vyhledávání: '"David W. Zhou"'
Autor:
Fangyun Tian, Laura D. Lewis, David W. Zhou, Gustavo A. Balanza, Angelique C. Paulk, Rina Zelmann, Noam Peled, Daniel Soper, Laura A. Santa Cruz Mercado, Robert A. Peterfreund, Linda S. Aglio, Emad N. Eskandar, G. Rees Cosgrove, Ziv M. Williams, R. Mark Richardson, Emery N. Brown, Oluwaseun Akeju, Sydney S. Cash, Patrick L. Purdon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
The neural mechanisms underpinning ketamine’s dissociative and antidepressant effects remain poorly understood. Here, the authors analyzed ketamine-induced brain dynamics with intracranial recordings in humans and found that ketamine engages differ
Externí odkaz:
https://doaj.org/article/da8d61cabb16496a94d360fce79c2d24
Autor:
Elisa C. Walsh, Johanna M. Lee, Kristina Terzakis, David W. Zhou, Sara Burns, Timothy M. Buie, Paul G. Firth, Erik S. Shank, Timothy T. Houle, Emery N. Brown, Patrick L. Purdon
Publikováno v:
Frontiers in Systems Neuroscience, Vol 12 (2018)
Patients with autism spectrum disorder (ASD) often require sedation or general anesthesia. ASD is thought to arise from deficits in GABAergic signaling leading to abnormal neurodevelopment. We sought to investigate differences in how ASD patients res
Externí odkaz:
https://doaj.org/article/ee723548f43740debce543a2b2aeb7ff
Autor:
John H Abel, Marcus A Badgeley, Benyamin Meschede-Krasa, Gabriel Schamberg, Indie C Garwood, Kimaya Lecamwasam, Sourish Chakravarty, David W Zhou, Matthew Keating, Patrick L Purdon, Emery N Brown
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0246165 (2021)
In current anesthesiology practice, anesthesiologists infer the state of unconsciousness without directly monitoring the brain. Drug- and patient-specific electroencephalographic (EEG) signatures of anesthesia-induced unconsciousness have been identi
Externí odkaz:
https://doaj.org/article/a5b7cc92e438450fa479ff7990253b3f
Autor:
Luis Paixao, Haoqi Sun, Jacob Hogan, Katie Hartnack, Mike Westmeijer, Anudeepthi Neelagiri, David W Zhou, Lauren M McClain, Eyal Y Kimchi, Patrick L Purdon, Oluwaseun Akeju, M Brandon Westover
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0259840 (2021)
BackgroundWe investigated the effect of delirium burden in mechanically ventilated patients, beginning in the ICU and continuing throughout hospitalization, on functional neurologic outcomes up to 2.5 years following critical illness.MethodsProspecti
Externí odkaz:
https://doaj.org/article/61502e21f91e4ddab46fa679e767ca9b
Autor:
William H. Curley, Yelena G. Bodien, David W. Zhou, Mary M. Conte, Andrea S. Foulkes, Joseph T. Giacino, Jonathan D. Victor, Nicholas D. Schiff, Brian L. Edlow
Publikováno v:
Cortex. 152:136-152
Tools assaying the neural networks that modulate consciousness may facilitate tracking of recovery after acute severe brain injury. The ABCD framework classifies resting-state EEG into categories reflecting levels of thalamocortical network function
Autor:
Veronica S. Weiner, David W. Zhou, Pegah Kahali, Emily P. Stephen, Robert A. Peterfreund, Linda S. Aglio, Michele D. Szabo, Emad N. Eskandar, Andrés F. Salazar-Gomez, Aaron L. Sampson, Sydney S. Cash, Emery N. Brown, Patrick L. Purdon
Publikováno v:
Proceedings of the National Academy of Sciences. 120
During propofol-induced general anesthesia, alpha rhythms measured using electroencephalography undergo a striking shift from posterior to anterior, termed anteriorization, where the ubiquitous waking alpha is lost and a frontal alpha emerges. The fu
Autor:
Fangyun Tian, Laura D. Lewis, David W. Zhou, Gustavo Balanza Villegas, Angelique C. Paulk, Rina Zelmann, Noam Peled, Daniel Soper, Laura A. Santa Cruz Mercado, Robert A. Peterfreund, Linda S. Aglio, Emad N. Eskandar, G Rees Cosgrove, Ziv M. Williams, Robert M. Richardson, Emery N. Brown, Oluwaseun Akeju, Sydney S. Cash, Patrick L. Purdon
SummarySubanesthetic doses of ketamine produce rapid and sustained anti-depressant effects in patients with treatment-resistant depression. Unfortunately, the usefulness of ketamine as a treatment is limited by its potential for abuse because of psyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::056f8142487b759c8ba0f6bf7c83f36a
https://doi.org/10.1101/2022.05.02.490333
https://doi.org/10.1101/2022.05.02.490333
Autor:
Veronica S. Weiner, David W. Zhou, Pegah Kahali, Emily P. Stephen, Robert A. Peterfreund, Linda S. Aglio, Michele D. Szabo, Emad N. Eskandar, Andrés F. Salazar-Gomez, Aaron L. Sampson, Sydney S. Cash, Emery N. Brown, Patrick L. Purdon
During propofol-induced general anesthesia, alpha rhythms undergo a striking shift from posterior to anterior, termed anteriorization. We combined human intracranial recordings with diffusion imaging to show that anteriorization occurs with opposing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c8fdb29d0f870138270177180847e45
https://doi.org/10.1101/2022.04.05.487190
https://doi.org/10.1101/2022.04.05.487190
Autor:
Mary M. Conte, Nicholas D. Schiff, Brian L. Edlow, Joseph T. Giacino, Yelena G. Bodien, William H. Curley, David W. Zhou, Jonathan D. Victor, Andrea S. Foulkes
Few reliable biomarkers of consciousness exist for patients with acute severe brain injury. Tools assaying the neural networks that modulate consciousness may allow for tracking of recovery. The mesocircuit model, and its instantiation as the ABCD fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::695db434b3400ba4302488c623a1bb9f
https://doi.org/10.1101/2021.09.08.21262992
https://doi.org/10.1101/2021.09.08.21262992
Autor:
Matthew Keating, Marcus A. Badgeley, Kimaya Lecamwasam, David W. Zhou, Benyamin Meschede-Krasa, Patrick L. Purdon, Gabriel Schamberg, John H. Abel, Emery N. Brown, Sourish Chakravarty, Indie C. Garwood
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0246165 (2021)
PLoS ONE
PLoS ONE
In current anesthesiology practice, anesthesiologists infer the state of unconsciousness without directly monitoring the brain. Drug- and patient-specific electroencephalographic (EEG) signatures of anesthesia-induced unconsciousness have been identi