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pro vyhledávání: '"David W. Sturdivant"'
A COMPARATIVE RESPIRATORY SENSITIZATION STUDY OF 2,4- AND 2,6-TOLUENE DIISOCYANATE USING GUINEA PIGS
Publikováno v:
Inhalation Toxicology. 12:605-615
The potential exposure of workers to both 2,4-toluene diisocyanate (2,4-TDI) and 2,6-TDI led to an investigation of the comparative respiratory sensitization potential of these two isomers. Separate groups of guinea pigs were either sham exposed or e
Autor:
Ronald N. Shiotsuka, Glenn S. Simon, A. Barry Astroff, Larry S. Andrews, Stephen G. Lake, David W. Sturdivant
Publikováno v:
Teratology. 62:205-213
Background: 1,6-Hexamethylene diisocyanate (HDI), a widely used chemical in commercial polyurethane manufacture, has been shown to affect the respiratory tract of experimental animals. However, its potential to affect neonatal development, particular
Publikováno v:
Inhalation toxicology. 18(9)
In this subacute inhalation toxicity study of 1,6-hexamethylene diisocyanate (HDI), groups of 10 male and 10 female Sprague-Dawley rats were exposed to 0, 0.005, 0.0175, or 0.150 ppm HDI vapor, 5 h/day, 5 days/wk for 15 exposure days and included ani
Autor:
Ronald N. Shiotsuka, David W. Sturdivant, Barry P. Stuart, A.B. Astroff, L.S Andrews, Glenn S. Simon, L.P Sheets
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 14(2)
1,6-Hexamethylene diisocyanate (HDI), a chemical widely used in commercial polyurethane products, was evaluated in a combined reproductive/developmental/neurotoxicity study. Sprague–Dawley rats ( n = 120; 15 per sex/dose group) were administered vi