Zobrazeno 1 - 7
of 7
pro vyhledávání: '"David W. Sandall"'
Autor:
Narmatha Satkunanathan, Bruce G. Livett, John Down, Ken R. Gayler, Zeinab Khalil, David W. Sandall
Publikováno v:
Brain Research. 1059:149-158
This paper demonstrates the capacity of the neuronal nicotinic acetylcholine receptor (nAChR) antagonist alpha-conotoxin Vc1.1 to inhibit pain responses in vivo. Vc1.1 suppressed pain behaviors when tested in two models of peripheral neuropathy of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566d1e262df7c9baf6048bb08c4cec05
https://doi.org/10.1016/j.brainres.2005.08.009
https://doi.org/10.1016/j.brainres.2005.08.009
Autor:
Zeinab Khalil, Ken R. Gayler, M. A. Polidano, Narmatha Satkunanathan, Bruce G. Livett, David W. Sandall, David A. Keays, John Down, David W. Greening
Publikováno v:
IEEE Engineering in Medicine and Biology Magazine. 24:79-84
This study aims to seek new drugs from the marine environment, with a particular focus on venomous animals, in particular the marine cone snail, Conus, a genus of predatory animal with a highly evolved venom and delivery apparatus. These remarkable c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0db5903e63bdc68f8222a4ad6371fe97
https://doi.org/10.1109/memb.2005.1411352
https://doi.org/10.1109/memb.2005.1411352
Autor:
Jonathan V. Sweedler, Ken R. Gayler, Jennifer A. Jakubowski, Bruce G. Livett, Wayne P. Kelley, David A. Keays, Jon-Paul Bingham, David W. Sandall
Publikováno v:
Journal of Mass Spectrometry. 39:548-557
A combination of cDNA cloning and detailed mass spectrometric analyses was employed to identify novel conotoxins from Conus victoriae. Eleven conotoxin sequences were determined using molecular methods: one belonging to the A superfamily (Vc1.1), six
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4d0bc998607ac874fe7c130fefa183
https://doi.org/10.1002/jms.624
https://doi.org/10.1002/jms.624
Autor:
David A. Keays, David W. Sandall, John Down, Narmatha Satkunanathan, Bruce G. Livett, V. Pham, Ken R. Gayler, Zeinab Khalil, X. Liping, M. A. Polidano
Publikováno v:
Biochemistry. 42:6904-6911
We describe the identification of a conopeptide sequence in venom duct mRNA from Conus victoriae that suppresses a vascular response to pain in the rat. PCR-RACE was used to screen venom duct cDNAs for those transcripts that encode specific antagonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3adcbe8290e65c32184fc412c48a1c28
https://doi.org/10.1021/bi034043e
https://doi.org/10.1021/bi034043e
Autor:
David W. Sandall, Alan J. Kohn, Jon-Paul Bingham, Gabriella Raybaudi Massilia, Bruce G. Livett, Jonathan V. Sweedler, Thomas F. Duda, John Down, Joseph R. Schultz
Publikováno v:
Science. 303:955-957
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1cef0ed982cb669704caafa2849a78f
https://doi.org/10.1126/science.303.5660.955
https://doi.org/10.1126/science.303.5660.955
Autor:
Jon-Paul Bingham, Peter Y.C. Yu, Joycelyn B. Chun, Steve Peigneur, David W. Sandall, Bruce G. Livett, Parashar Thapa, Jeffrey W. Milisen, Jan Tytgat, Zachary L. Bergeron, Margaret R. Baker
Publikováno v:
Peptides. 49
Cone snail venoms provide a largely untapped source of novel peptide drug leads. To enhance the discovery phase, a detailed comparative proteomic analysis was undertaken on milked venom from the mollusk-hunting cone snail, Conus textile, from three d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563dc309361692378c8fce863df42ac6
https://pubmed.ncbi.nlm.nih.gov/24055806
https://pubmed.ncbi.nlm.nih.gov/24055806
Autor:
Zeinab Khalil, John Down, David W. Sandall, David A. Keays, Narmatha Satkunanathan, Bruce G. Livett, Ken R. Gayler
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 48(7)
Pain therapeutics discovered by molecular mining of the expressed genome of Australian predatory cone snails are providing lead compounds for the treatment of neurological diseases such as multiple sclerosis, shingles, diabetic neuropathy and other p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4ba63e1f747b9226b943b38615b4c6
https://pubmed.ncbi.nlm.nih.gov/16979678
https://pubmed.ncbi.nlm.nih.gov/16979678