Zobrazeno 1 - 10
of 360
pro vyhledávání: '"David W. Reid"'
Autor:
Amy Pham, Kellynn K. Y. Tan, Emma L. Ledger, Daniel J. Smith, David W. Reid, Lucy Burr, Daniel C. Chambers, Timothy J. Wells
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionThe Burkholderia cepacia complex encompasses a group of gram-negative opportunistic pathogens that cause chronic lung infections in people with cystic fibrosis. Distinct from other respiratory pathogens, Burkholderia causes a unique clini
Externí odkaz:
https://doaj.org/article/d9ab8ee188854e8f8d5d6502c32d4dfc
Autor:
Alicia A. Bicknell, David W. Reid, Marissa C. Licata, Adriana K. Jones, Yi Min Cheng, Mengying Li, Chiaowen Joyce Hsiao, Christopher S. Pepin, Mihir Metkar, Yevgen Levdansky, Brian R. Fritz, Elizaveta A. Andrianova, Ruchi Jain, Eugene Valkov, Caroline Köhrer, Melissa J. Moore
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114098- (2024)
Summary: Developing an effective mRNA therapeutic often requires maximizing protein output per delivered mRNA molecule. We previously found that coding sequence (CDS) design can substantially affect protein output, with mRNA variants containing more
Externí odkaz:
https://doaj.org/article/7b3fb817ec414bcf9bdcba69344c3e0c
Autor:
Amy Pham, James G. Volmer, Daniel C. Chambers, Daniel J. Smith, David W. Reid, Lucy Burr, Timothy J. Wells
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionThe Burkholderia cepacia complex (BCC) encompasses a group of at least 22 genetically distinct gram-negatives bacterial species ubiquitous in nature. Recognised as a group of genetically and phenotypically flexible species, the BCC inhabi
Externí odkaz:
https://doaj.org/article/ea9937cea04742e1b192a4c3167a133c
Autor:
Pramila Maniam, Ama-Tawiah Essilfie, Murugan Kalimutho, Dora Ling, David M. Frazer, Simon Phipps, Gregory J. Anderson, David W. Reid
Publikováno v:
Biological Research, Vol 54, Iss 1, Pp 1-13 (2021)
Abstract Background Defective chloride transport in airway epithelial cells (AECs) and the associated lung disease are the main causes of morbidity and early mortality in cystic fibrosis (CF). Abnormal airway iron homeostasis and the presence of lipi
Externí odkaz:
https://doaj.org/article/bb6dd0f664b5421b87098d1ad69a917b
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-19 (2020)
Abstract Background The protein homeostasis (proteostasis) network maintains balanced protein synthesis, folding, transport, and degradation within a cell. Failure to maintain proteostasis is associated with aging and disease, leading to concerted ef
Externí odkaz:
https://doaj.org/article/eb52678afc37466ab76c9fd4b63de5c2
Autor:
Ama‐Tawiah Essilfie, Neralee Houston, Pramila Maniam, Gunter Hartel, Satomi Okano, David W. Reid
Publikováno v:
Respirology. 28:533-542
Autor:
Champa N. Ratnatunga, Viviana P. Lutzky, Andreas Kupz, Denise L. Doolan, David W. Reid, Matthew Field, Scott C. Bell, Rachel M. Thomson, John J. Miles
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The incidence and number of deaths from non-tuberculous mycobacterial (NTM) disease have been steadily increasing globally. These lesser known “cousins” of Mycobacterium tuberculosis (TB) were once thought to be harmless environmental saprophytic
Externí odkaz:
https://doaj.org/article/ef45c5bca634442f8af08ae637843df8
Autor:
Seth T. Kazmer, Gunter Hartel, Harley Robinson, Renee S. Richards, Kexin Yan, Sebastiaan J. van Hal, Raymond Chan, Andrew Hind, David Bradley, Fabian Zieschang, Daniel J. Rawle, Thuy T. Le, David W. Reid, Andreas Suhrbier, Michelle M. Hill
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 351 (2022)
Fourier transform infrared (FTIR) spectroscopy provides a (bio)chemical snapshot of the sample, and was recently used in proof-of-concept cohort studies for COVID-19 saliva screening. However, the biological basis of the proposed technology has not b
Externí odkaz:
https://doaj.org/article/0bf9f25b7d384723bf59229745d07c42
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The epidemic of obesity and diabetes has markedly spurred the research interest in adipocyte biology. Brown adipocytes are specialized for energy expenditure and of therapeutic interest for treatment of metabolic diseases, but how brown adip
Externí odkaz:
https://doaj.org/article/42814b23c8b94a7fb4c6fb81551195e8
Autor:
Vernon Keegan, Kate MacMorran, Julieta Castellini, Daniel Henderson, Deanne Curtin, Vanessa L. Moore, George Tay, Karen Hay, David W. Reid
Publikováno v:
Internal Medicine Journal. 52:63-68
The impact of an acute pulmonary exacerbation of cystic fibrosis (CF) on sleep quality has not been established. Patients have greater burden of symptoms, higher intensity of therapy and are often admitted to hospital outside of their usual sleeping