Zobrazeno 1 - 10
of 188
pro vyhledávání: '"David W. Pascual"'
Autor:
Ali Akgul, Christian Furlan Freguia, Massimo Maddaloni, Carol Hoffman, Alexandria Voigt, Cuong Q. Nguyen, Neil A. Fanger, Gary R. Fanger, David W. Pascual
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Sjögren’s Syndrome (SjS) results in loss of salivary and lacrimal gland excretion due to an autoimmune attack on these secretory glands. Conventional SjS treatments address the symptoms, but not the cause of disease. Recognizing this defi
Externí odkaz:
https://doaj.org/article/77ebacf05d39426b90599056829fc0d8
Publikováno v:
Microorganisms, Vol 12, Iss 1, p 169 (2024)
Susceptibility to brucellosis remains prevalent, even in herds vaccinated with conventional vaccines. Efforts are underway to develop an improved brucellosis vaccine, and possibly a universal vaccine, given that Brucella species are highly homologous
Externí odkaz:
https://doaj.org/article/0221299f62f04ea1a3868c239421af3f
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Brucellosis is a disease of livestock that is commonly asymptomatic until an abortion occurs. Disease in humans results from contact of infected livestock or consumption of contaminated milk or meat. Brucella zoonosis is primarily caused by one of th
Externí odkaz:
https://doaj.org/article/4d3dbc06d6264cf594d150018a86c42d
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Re-emerging zoonotic pathogen Brucella spp. continues to impact developing countries and persists in expanding populations of wildlife species in the US, constantly threatening infection of our domestic herds. The development of improved animal and h
Externí odkaz:
https://doaj.org/article/1dc1b66c286c4b6584653433548f493b
Autor:
Lisa E Emerson, Hailey Barker, Terri Tran, Samantha Barker, Samantha Enslow, Mark Ou, Carol Hoffman, Melissa Jones, David W. Pascual, Mariola J. Edelmann
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 9, Pp n/a-n/a (2022)
Abstract Small extracellular vesicles (sEVs) produced by antigen‐presenting cells represent a novel mechanism of cell‐to‐cell communication. The sEVs have been shown to drive Th1‐type adaptive immune responses against intracellular infections
Externí odkaz:
https://doaj.org/article/87ce3dc4a29d465999950e6373bb020c
Autor:
Ali Akgul, Massimo Maddaloni, Sang Mu Jun, Andrew S. Nelson, Vanessa Aguilera Odreman, Carol Hoffman, Ella Bhagyaraj, Alexandria Voigt, Jeffrey R. Abbott, Cuong Q. Nguyen, David W. Pascual
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-16 (2021)
Abstract Background Sjögren’s syndrome (SjS), one of the most common autoimmune diseases, impacts millions of people annually. SjS results from autoimmune attack on exocrine (salivary and lacrimal) glands, and women are nine times more likely to b
Externí odkaz:
https://doaj.org/article/248c1b9b813c47b9965b4b7f38ff610f
Autor:
Ella Bhagyaraj, Hongbin Wang, Xinghong Yang, Carol Hoffman, Ali Akgul, Zakia I. Goodwin, David W. Pascual
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Past studies with the live, double-mutant B. abortus (znBAZ) strain resulted in nearly complete protection of mice against pulmonary challenge with wild-type (wt) Brucella via a dominant CD8+ T cell response. To understand the contribution innate imm
Externí odkaz:
https://doaj.org/article/a9226dfbc2354271bb2707727f93517f
Publikováno v:
BMC Microbiology, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Human granulocytic anaplasmosis (HGA) is a tick-borne disease caused by the etiologic agent Anaplasma phagocytophilum. HGA was designated a nationally notifiable disease in the United States in 1998. Currently there are no vaccine
Externí odkaz:
https://doaj.org/article/bff1a21d74d64e6f832cc37b1560bf75
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
IL-35, a relatively newly discovered cytokine belonging to the larger IL-12 family, shows unique anti-inflammatory properties, believed to be associated with dedicated receptors and signaling pathways. IL-35 plays a pivotal role in the development an
Externí odkaz:
https://doaj.org/article/1fe78a465d144211bbfddc72d8713659
Publikováno v:
The Journal of Immunology. 210:1576-1588
The Brucella abortus double-mutant (ΔznuA ΔnorD Brucella abortus-lacZ [znBAZ]) was assessed for its protective efficacy after vaccination with a single nasal dose. Superior protection was achieved in znBAZ-vaccinated mice against pulmonary, wild-ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfc32b93f9edb546f0df361f1e982b80
https://doi.org/10.4049/jimmunol.2300071
https://doi.org/10.4049/jimmunol.2300071