Výsledky vyhledávání - "David W. Nyman"

Phase I and Pharmacokinetics Trial of ABI-007, a Novel Nanoparticle Formulation of Paclitaxel in Patients With Advanced Nonhematologic Malignancies

Autor: Kelly Richardson, Daniel D. Von Hoff, Evan M. Hersh, Neil Desai, David W. Nyman, Vuong Trieu, Kimberley J. Campbell, Michael J. Hawkins, Kristen Long

Publikováno v: Journal of Clinical Oncology. 23:7785-7793

Purpose ABI-007 is a novel solvent-free, albumin-bound, 130-nm particle formulation of paclitaxel designed to avoid solvent-related toxicities and to deliver paclitaxel to tumors via molecular pathways involving an endothelial cell-surface albumin re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c741b7684a850221bf11aef643b843
https://doi.org/10.1200/jco.2004.00.6148

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Selenium and selenomethionine levels in prostate cancer patients

Autor: Raymond B. Nagle, David W. Nyman, Michael J. Kopplin, A. Jay Gandolfi, M. Suzanne Stratton, Bruce L. Dalkin

Publikováno v: Cancer Detection and Prevention. 28:8-16

Objective : Selenium (Se) and selenomethionine (Se-Met) have been identified as potential chemopreventive agents of prostate cancer. Using an assay for the speciation (separation and identification) and quantification of selenoamino acids, Se-Met was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8585ed24357b6e73d960ef84d5fc6f1f
https://doi.org/10.1016/j.cdp.2003.11.002

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A Multi-Center, Open-Label Study To Evaluate the Safety and Efficacy of Pentostatin, Cytoxan, and Rituxan (PCR) in the Treatment of Previously Untreated or Treated Bulky Stage II or Stage III or IV, Low-Grade B-Cell NHL

Autor: David W. Nyman, Naveed M. Chowhan, Yudhishtra Markan, Raul R. Mena, Neal P. Christiansen

Publikováno v: Blood. 106:4750-4750

Introduction: The decision to treat indolent B-cell NHL is often based on progressing bulky disease, worsening symptoms, and increasing hematologic derangement. When treatment is indicated, these lymphoproliferative disorders are very sensitive to co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd61f3bc2a2d8277b52ebef01a63973d
https://doi.org/10.1182/blood.v106.11.4750.4750

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A phase I trial of ABI-007, nanoparticle paclitaxel, administered to patients with advanced non-hematologic malignancies

Autor: D. D. Von Hoff, David W. Nyman, Vuong Trieu, Kelly Richardson, Evan M. Hersh, K. Patrick, Kimberley J. Campbell, Neil P. Desai

Publikováno v: Journal of Clinical Oncology. 22:2027-2027

2027 Background: To evaluate the safety/tolerability, maximum tolerated dose (MTD), and anti-tumor effect of nanoparticle paclitaxel (ABI-007). This novel Cremophor-free formulation was administere...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5458d89ce12bd6966b3a2e6bdc147569
https://doi.org/10.1200/jco.2004.22.90140.2027

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Effects of metoprolol and propranolol on theophylline elimination

Autor: Kenneth A. Conrad, David W. Nyman

Publikováno v: Clinical Pharmacology and Therapeutics. 28:463-467

The effects of beta adrenergic blockade on theophylline elimination were studied in nine nofmal subjects. Oral propranolol, 40 mg every 6 hr, induced a fall in theophylline clearance from 0.0464 +/- 0.0294 +/- 0.0129 l/kg/hr (p < 0.001). Oral metopro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce69e4978ff05eabd3f54938ce8f672
https://doi.org/10.1038/clpt.1980.189

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