Zobrazeno 1 - 10
of 17
pro vyhledávání: '"David W. Moss"'
Autor:
David W. Moss, Timothy E. Bates
Publikováno v:
European Journal of Neuroscience. 13:529-538
Activation of murine microglial and macrophage cell lines with lipopolysaccharide (LPS) and interferon-gamma (IFN-gamma) resulted in the induction of the inducible form of nitric oxide synthase (NOS) and the release of micromolar amounts of NO into t
Autor:
Paul Monaghan, David W. Moss
Publikováno v:
Cell Biology International. 20:121-125
Gap junctional communication plays a vital role in embryogenesis, cell differentiation and the co-ordination of tissue responses. Gap junctions are formed by a family of closely-related proteins called connexins which show tissue-specific patterns of
Publikováno v:
European Journal of Pharmacology: Molecular Pharmacology. 289:41-48
A complementary DNA (cDNA) encoding murine inducible nitric oxide synthase was cloned from activated J774 macrophages. Expression of this cDNA in a baculovirus-insect cell system allowed comparison of the recombinant enzyme with the native homologue.
Publikováno v:
European Journal of Immunology. 21:3009-3014
Inbred strains of mice differ considerably in their innate resistance to leishmanial infection. BALB/c mice are highly susceptible to cutaneous leishmaniasis caused by Leishmania major, whereas CBA mice are resistant. We now show that this resistance
Publikováno v:
British Journal of Pharmacology. 113:496-498
1. We have investigated, using rat aortic rings, whether exogenous nitric oxide (NO) gas affects the activity or expression of the inducible, Ca(2+)-independent NO synthase. 2. Incubation of rings with lipopolysaccharide (LPS, S. typhosa) for 6 h res
Autor:
Catherine J. Waterfield, Mariko Kudo, Susan H. Kenyon, Anna Nicolaou, Daniel S. Asker, William A. Gibbons, Timothy E. Bates, David W. Moss, J. A. Timbrell
Publikováno v:
Biochemical pharmacology. 57(11)
The effect of the industrial chemical, hydrazine (4-12 mM), on methionine synthase (EC 2.1.1.13) activity and levels of the sulphur amino acids homocysteine, cysteine, and taurine as well as GSH were investigated in vitro in isolated rat hepatocyte s
Autor:
Paul Monaghan, Xiao-Yuan Chen, Catherine Clarke, Nina Perusinghe, David W. Moss, William Howard Evans
Publikováno v:
Experimental cell research. 223(1)
Expression of the gap junction proteins (connexins) in human breast epithelium was studied in vivo and in vitro. A panel of sequence-specific anti-peptide antibodies was used to examine four connexin (Cx) isoforms by indirect immunofluorescence label
Autor:
Ian G. Charles, D C Jenkins, L.S. Holmes, P Rhodes, Piers C. Emson, K Westmore, David W. Moss, Salvador Moncada, Sally A. Baylis, L L Thomsen
A subclone of the human colon adenocarcinoma cell line DLD-1, which grew reproducibly as subcutaneous tumors in nude mice, was isolated. Such cells, when engineered to generate nitric oxide (NO) continuously, grew more slowly in vitro than the wild-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864eda3d34e5a37fa5ba6f99214abcca
https://hdl.handle.net/10453/13314
https://hdl.handle.net/10453/13314
Autor:
Catherine A. O'Donnell, Damo Xu, Alison Severn, David W. Moss, Jacqueline Doyle, Sara J. Brett, Ludmila M. C. C. Leal, Foo Y. Liew
Publikováno v:
European journal of immunology. 23(7)
Murine macrophages produce nitric oxide (NO) from L-arginine on stimulation with lipopolysaccharide (LPS), alone or with interferon-gamma (IFN-gamma). The effect of incubation of macrophages with low concentrations of LPS on NO synthesis on subsequen
Publikováno v:
European journal of immunology. 23(2)
The outcome of cutaneous leishmaniasis is dependent on the balance of Th1 and Th2 cells. In the murine model, Th1 cells are host-protective whereas the Th2 cells are disease-promoting. However, the in vivo role of interleukin-4 (IL-4), a signature pr