Zobrazeno 1 - 10
of 44
pro vyhledávání: '"David W. Kimmel"'
Publikováno v:
Neuro-Oncology. 6:55-62
Paraneoplastic neurological disorders are devastating remote effects of malignancy. Despite compelling evidence of an autoimmune pathogenesis, empiric immunomodulatory treatment of these disorders is often ineffective. However, very few systematic st
Autor:
Kazunari Sato, Issei Tachibana, David W. Kimmel, Justin S. Smith, Sandra M. Hosek, Robert B. Jenkins
Publikováno v:
American Journal of Medical Genetics. 92:136-141
Epidemiological studies suggest that some familial aggregations of glioma may be due to inherited predisposition. Many genes involved in familial cancers are frequently altered in the corresponding sporadic forms. We have investigated several genes k
Autor:
Arie Perry, Bernd W. Scheithauer, Robert B. Jenkins, Tom J. Borell, Judith R. O'Fallon, Kari L. Anderl, David W. Kimmel, Chiao H. Wang, Burt G. Feuerstein
Publikováno v:
American Journal of Clinical Pathology. 112:801-809
Inactivation of the p53 gene is a common early event of astrocytoma tumorigenesis. Alternatively, since the p16, retinoblastoma (RB), and CDK4 genes have been implicated in malignant progression, detection of losses or amplifications of these genes i
Autor:
Scott D. Jewell, Allan J. Yates, David W. Kimmel, Theodore C. Comas, Peter C. Burger, Bernd W. Scheithauer, Tadashi Tai, Dennis K. Pearl
Publikováno v:
Neuro-Oncology. 1:261-267
Immunohistochemical staining intensity for ganglioside GD1b was determined for 108 human neuroectodermal tumors. Most of the tissue elements that immunostained were tumor cells; only a few axons and occasional neurons reacted in some specimens. All p
Autor:
Sandra M. Smith, David W. Kimmel, Bernd W. Scheithauer, Paul L. Schaefer, Jan C. Buckner, Roscoe F. Morton, Robert B. Jenkins, Ralph Levitt, Eunice M. Hill, Michelle R. Mahoney, Arie Perry, James Krook, Thomas J. Sebo, Judith R. O'Fallon, Loren K. Tschetter
Publikováno v:
Cancer. 86:672-683
BACKGROUND The biologic behavior of anaplastic (World Health Organization Grade III) astrocytomas and oligoastrocytomas is highly variable, ranging from rapid progression to prolonged survival. It is difficult to predict the outcome of an individual
Autor:
Thomas J. Borell, Benjamin Alderete, Arie Perry, Bernd W. Scheithauer, Judith R. O'Fallon, Allan J. Yates, Justin S. Smith, David W. Kimmel, Yuriko A. Minn, Sandra M. Hosek, Robert B. Jenkins, Peter C. Burger, Burt G. Feuerstein, Gayatry Mohapatra
Publikováno v:
Oncogene. 18:4144-4152
Allelic alterations of chromosomes 1 and 19 are frequent events in human diffuse gliomas and have recently proven to be strong predictors of chemotherapeutic response and prolonged survival in oligodendrogliomas (Cairncross et al., 1998; Smith et al.
Publikováno v:
Neurology. 51:1504-1507
We report two patients with paraneoplastic limbic and brainstem encephalitis associated with occult nonmetastatic testicular seminoma. In each patient, the neoplasm was detectable only by testicular ultrasonography. Male patients with this syndrome i
Publikováno v:
Cancer. 83:1602-1606
BACKGROUND Peroneal neuropathies in patients with systemic cancer previously have been attributed to weight loss, but to the authors' knowledge other associated conditions have not been assessed, and the outcome of peroneal neuropathies in cancer pat
Autor:
Jan C. Buckner, Bernd W. Scheithauer, David W. Kimmel, Evanthia Galanis, Paula J. Schomberg, David G. Piepgras
Publikováno v:
Cancer. 82:1915-1920
BACKGROUND Meningeal hemangiopericytoma is an uncommon neoplasm with a high propensity for recurrence. The purpose of this study was to analyze the efficacy of different treatment options in patients with recurrent disease. METHODS The records of all
Publikováno v:
Neurology. 50:652-657
Type 1 antineuronal nuclear autoantibody (ANNA-1, also known as "anti-Hu") is a marker of neurologic autoimmunity that is highly associated with small-cell lung carcinoma (SCLC). To determine the spectrum of symptoms and signs as well as the frequenc