Zobrazeno 1 - 10
of 36
pro vyhledávání: '"David W. Gohara"'
Publikováno v:
Viruses, Vol 7, Iss 11, Pp 5962-5986 (2015)
The genomes of RNA viruses are relatively small. To overcome the small-size limitation, RNA viruses assign distinct functions to the processed viral proteins and their precursors. This is exemplified by poliovirus 3CD protein. 3C protein is a proteas
Externí odkaz:
https://doaj.org/article/f9fc57799394463385045e23b3550657
Autor:
Calvin Yeager, Griffin Carter, David W Gohara, Neela H Yennawar, Eric J Enemark, Jamie J Arnold, Craig E Cameron
Publikováno v:
Nucleic acids research. 50(20)
The enteroviral 2C protein is a therapeutic target, but the absence of a mechanistic framework for this enzyme limits our understanding of inhibitor mechanisms. Here, we use poliovirus 2C and a derivative thereof to elucidate the first biochemical me
Autor:
Christopher S Eickhoff, Xiuli Zhang, Jose R Vasconcelos, R Geoffrey Motz, Nicole L Sullivan, Kelly O'Shea, Nicola Pozzi, David W Gohara, Jennifer R Blase, Enrico Di Cera, Daniel F Hoft
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005896 (2016)
Trypanosoma cruzi infection is controlled but not eliminated by host immunity. The T. cruzi trans-sialidase (TS) gene superfamily encodes immunodominant protective antigens, but expression of altered peptide ligands by different TS genes has been hyp
Externí odkaz:
https://doaj.org/article/c2a58035b8ad400d8de3e82cee2f1e8b
Autor:
Cheri A Schaaf, Ziva Misulovin, Maria Gause, Amanda Koenig, David W Gohara, Audrey Watson, Dale Dorsett
Publikováno v:
PLoS Genetics, Vol 9, Iss 6, p e1003560 (2013)
Cohesin is crucial for proper chromosome segregation but also regulates gene transcription and organism development by poorly understood mechanisms. Using genome-wide assays in Drosophila developing wings and cultured cells, we find that cohesin func
Externí odkaz:
https://doaj.org/article/f33621fa633540abb4c74cce7db9e9c7
Autor:
Charles C. Kirkpatrick, David W. Gohara, Katherine E Richardson, Brent M. Znosko, Miranda S Adams
Publikováno v:
Biochemistry
There is an abundance of RNA sequence information available due to the efforts of sequencing projects. However, current techniques implemented to solve the tertiary structures of RNA, such as NMR and X-ray crystallography, are difficult and time-cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb18b44b9cdf6c459472288e2560ec67
https://europepmc.org/articles/PMC7745247/
https://europepmc.org/articles/PMC7745247/
Autor:
David W. Gohara, Mee-Ngan Frances Yap
Publikováno v:
Current Genetics
In response to nutrient deprivation and environmental insults, bacteria conjoin two copies of non-translating 70S ribosomes that form the translationally inactive 100S dimer. This widespread phenomenon is believed to prevent ribosome turnover and ser
Autor:
Keith M Callenberg, Om P Choudhary, Gabriel L de Forest, David W Gohara, Nathan A Baker, Michael Grabe
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Electrostatic forces are one of the primary determinants of molecular interactions. They help guide the folding of proteins, increase the binding of one protein to another and facilitate protein-DNA and protein-ligand binding. A popular method for co
Externí odkaz:
https://doaj.org/article/4a9c29acdfd148aeabae11e38e91170c
Autor:
Javier Seravalli, P. John Hart, Jaekwon Lee, Enrico Di Cera, Xiaobin Wu, Heejeong Kim, David W. Gohara, Won Hee Jung, Joseph J. Barycki, Daniel J. Kosman
Publikováno v:
Journal of Biological Chemistry. 291:9796-9806
Acquisition and distribution of metal ions support a number of biological processes. Here we show that respiratory growth of and iron acquisition by the yeast Saccharomyces cerevisiae relies on potassium (K(+)) compartmentalization to the trans-Golgi
Autor:
Robert Konecny, David Ryan Koes, Nathan A. Baker, Jens Erik Nielsen, Dave Engel, Kyle E. Monson, Robert Krasny, Peter Li, Lisa E. Felberg, Karina Liles, Juan Brandi, David H. Brookes, J. Andrew McCammon, Guo-Wei Wei, Leighton Wilson, Minju Chun, Michael Holst, Elizabeth Jurrus, Todd J. Dolinsky, Teresa Head-Gordon, Weihua Geng, Keith T. Star, Jiahui Chen, David W. Gohara
Publikováno v:
Protein science : a publication of the Protein Society, vol 27, iss 1
Jurrus, E; Engel, D; Star, K; Monson, K; Brandi, J; Felberg, LE; et al.(2018). Improvements to the APBS biomolecular solvation software suite. Protein Science, 27(1), 112-128. doi: 10.1002/pro.3280. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/3cg341d5
Jurrus, E; Engel, D; Star, K; Monson, K; Brandi, J; Felberg, LE; et al.(2018). Improvements to the APBS biomolecular solvation software suite. Protein Science, 27(1), 112-128. doi: 10.1002/pro.3280. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/3cg341d5
© 2017 The Protein Society The Adaptive Poisson–Boltzmann Solver (APBS) software was developed to solve the equations of continuum electrostatics for large biomolecular assemblages that have provided impact in the study of a broad range of chemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc0647139a37cb36f141e1a3b52dbce
https://escholarship.org/uc/item/3cg341d5
https://escholarship.org/uc/item/3cg341d5
Autor:
David W. Gohara
Publikováno v:
Biophysical chemistry. 234
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