Zobrazeno 1 - 10
of 15
pro vyhledávání: '"David W. Erickson"'
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Fast-growing bacteria produce many proteins in excess of what seems optimal for exponential growth. Here, the authors present a mathematical model and experimental evidence supporting that this overexpression serves as a strategic reserve to quickly
Externí odkaz:
https://doaj.org/article/3544e922e215469b80235c1a59ad032b
Autor:
Sheng Hui, Josh M Silverman, Stephen S Chen, David W Erickson, Markus Basan, Jilong Wang, Terence Hwa, James R Williamson
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 2, Pp 1-15 (2015)
Abstract A central aim of cell biology was to understand the strategy of gene expression in response to the environment. Here, we study gene expression response to metabolic challenges in exponentially growing Escherichia coli using mass spectrometry
Externí odkaz:
https://doaj.org/article/e80083352dca42eeb988330785bbe81f
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 11, p e1002265 (2011)
Cells employ a myriad of signaling circuits to detect environmental signals and drive specific gene expression responses. A common motif in these circuits is inducible auto-activation: a transcription factor that activates its own transcription upon
Externí odkaz:
https://doaj.org/article/9f435061163d4688876a2885c8dc6e3d
Autor:
Victoria A. Campbell, Ely Wolin, Trevor A. Thompson, Kamal D. Singh, Joseph S. Fotos, Jonathan Muldermans, Cameron C. Foster, T W T William, Joseph M. Yetto, Vicki Nagano, David W. Erickson, John Randolph Dryden, John P. Lichtenberger, Mickaila J. Johnston, Kathryn R. Wagner, Brady S. Davis, Brian J. Lewis, James Gullo, Cathy Zhou, Britain A. Gailliot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa218e50e899ba46564cae3d0a682342
https://doi.org/10.1055/b-006-160183
https://doi.org/10.1055/b-006-160183
Characterization and Impact of Secondary Flows in a Discrete Passage Centrifugal Compressor Diffuser
Publikováno v:
Volume 2B: Turbomachinery.
Truncating the exit of a discrete passage centrifugal compressor diffuser is observed to enhance a research compressor’s stall line. By interrogating the experimental data along with a set of well-designed Reynolds-Averaged Navier Stokes computatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88b1618e1c19a3e33a84461d938c63d
https://doi.org/10.1115/gt2018-76231
https://doi.org/10.1115/gt2018-76231
Autor:
David W. Erickson, James T. Dobbins, Gregory M. Sturgeon, W. Paul Segars, Jered R. Wells, Joseph Y. Lo, Ehsan Samei
Publikováno v:
Medical Physics. 43:23-32
Purpose: To create a database of highly realistic and anatomically variable 3D virtual breast phantoms based on dedicated breast computed tomography (bCT) data. Methods: A tissue classification and segmentation algorithm was used to create realistic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd6fcbfc5210e489922e8267a2b0a717
https://doi.org/10.1118/1.4937597
https://doi.org/10.1118/1.4937597
Publikováno v:
Nature communications, vol 8, iss 1
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Nature Communications
The overexpression of proteins is a major burden for fast-growing bacteria. Paradoxically, recent characterization of the proteome of Escherichia coli found many proteins expressed in excess of what appears to be optimal for exponential growth. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8738727ebae3809f4b7b4d1fac614b14
https://doi.org/10.1038/s41467-017-01242-8
https://doi.org/10.1038/s41467-017-01242-8
Autor:
David W. Erickson, Vadim Patsalo, Terence Hwa, James R. Williamson, Severin Schink, Ulrich Gerland
Publikováno v:
Nature. 551(7678)
A grand challenge of systems biology is to predict the kinetic responses of living systems to perturbations starting from the underlying molecular interactions. Changes in the nutrient environment have long been used to study regulation and adaptatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5cb8bbb668e3d107a79da2cbaa40f7
https://pubmed.ncbi.nlm.nih.gov/29239769
https://pubmed.ncbi.nlm.nih.gov/29239769
Autor:
Stephen S. Chen, Markus Basan, Josh M. Silverman, James R. Williamson, Sheng Hui, David W. Erickson, Jilong Wang, Terence Hwa
Publikováno v:
Molecular Systems Biology
A central aim of cell biology was to understand the strategy of gene expression in response to the environment. Here, we study gene expression response to metabolic challenges in exponentially growing Escherichia coli using mass spectrometry. Despite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a20641f5fffec19f39897789dc07b9
https://doi.org/10.15252/msb.20145697
https://doi.org/10.15252/msb.20145697
Publikováno v:
Journal of Physics A: Mathematical and General. 38:L659-L665
We present high-precision Monte Carlo data for the phase diagram of a two-species driven diffusive system, reminiscent of traffic across a narrow bridge. Earlier studies reported two phases with broken symmetry; the existence of one of these has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa590bef7cd2c0fc6da5608b43dd39c3
https://doi.org/10.1088/0305-4470/38/41/l01
https://doi.org/10.1088/0305-4470/38/41/l01