Zobrazeno 1 - 10
of 14
pro vyhledávání: '"David W. Duhme"'
Publikováno v:
Clinical Pharmacology & Therapeutics. 16:284-287
Publikováno v:
Clinical Pharmacology & Therapeutics. 16:813-816
Publikováno v:
Pharmacology. 14:182-190
Eight healthy males received 0.75 mg of digoxin by ten modes of administration in a single-dose multicrossover bioavilability study. Digoxin concentration in multiple blood samples drawn after each dose and in six consecutive 24-hour urine collection
Publikováno v:
American Journal of Health-System Pharmacy. 32:508-517
Practical clinical aspects of the evaluation and treatment of essential hypertension are reviewed. Drug therapy discussed includes diuretics, and as adjunctive therapy, sympathoplegic agents, peripheral vasodilators and beta blockers. Also covered ar
Publikováno v:
American Heart Journal. 94:6-13
Of 17,068 hospitalized medical patients monitored in a drug surveillance program, 2,367 (13.9 per cent) received furosemide. Of these patients, 53 per cent were hospitalized with a primary (first) diagnosis of cardiovascular disease; many other patie
Publikováno v:
New England Journal of Medicine. 289:651-654
Methods for testing digoxin bioavailability were compared in single-dose crossover studies using eight healthy male subjects. Digoxin (0.75 mg) was given by intravenous infusion, intramuscular injection, oral elixir and oral tablet. Multiple serum co
Autor:
William J. Tilstone, Thomas W. Smith, David J. Greenblatt, R.G. Stoll, David W. Duhme, P. C. Reavey, John G. Wagner, Jan Koch-Weser
Publikováno v:
Clinical Pharmacology & Therapeutics. 17:117-119
In a recent publication in this JOURNAL, Greenblatt and associates3 recommended that the “administration of digoxin by slow infusion is preferable as an intravenous standard in bioavailability testing” as opposed to a rapid intravenous injection.
Autor:
Jan Koch-Weser, David W. Duhme, Bernard J. Ransil, David J. Greenblatt, Jerold S. Harmatz, Thomas W. Smith
Publikováno v:
Journal of clinical pharmacology. 16(7)
Creatinine excretion was studied in eight healthy males who collected 54 to 97 24-hour urine specimens. Significant differences among subjects in mean creatinine excretion were only partly explained by differences in body weight and surface area. Con
Publikováno v:
Clinical pharmacology and therapeutics. 16(3)
Publikováno v:
Annals of internal medicine. 80(4)