The correlation between oxygen saturation indices and the standard obstructive sleep apnea severity

Autor: Siraj Omar Wali, Bahaa Abaalkhail, Ibrahim AlQassas, Faris Alhejaili, David W Spence, Seithikurippu R Pandi-Perumal

Publikováno v: Annals of Thoracic Medicine, Vol 15, Iss 2, Pp 70-75 (2020)

OBJECTIVE: Currently accepted guidelines categorize obstructive sleep apnea (OSA) severity according to the Apnea–Hypopnea Index (AHI). However, it is unclear how to best define OSA severity. The present study sought to evaluate the concurrent vali

Externí odkaz: https://doaj.org/article/9792f61b3b994fb689c840288d8ea4aa

Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production

Autor: Catherine M. Collins, David W. Spence, Kate M. J. de Mattos-Shipley, Colin M. Lazarus, Amanda J. Hartley, Fabrizio Alberti, Andy M. Bailey, Karen O'Dwyer, Sreedhar Kilaru, Patrick L. Hayes, Russell J. Cox, Gary D. Foster, Christine L. Willis, Alison Michelle Griffin

Publikováno v: Scientific Reports
Bailey, A M, Alberti, F, Kilaru, S, Collins, C M, De Mattos-Shipley, K, Hartley, A J, Hayes, P, Griffin, A, Lazarus, C M, Cox, R J, Willis, C L, O'Dwyer, K, Spence, D W & Foster, G D 2016, ' Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production ', Scientific Reports, vol. 6, srep25202 . https://doi.org/10.1038/srep25202

Semi-synthetic derivatives of the tricyclic diterpene antibiotic pleuromutilin from the basidiomycete Clitopilus passeckerianus are important in combatting bacterial infections in human and veterinary medicine. These compounds belong to the only new

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2903429b58858c5740d9e8ef58fd94a8
http://wrap.warwick.ac.uk/96721/1/WRAP-Identification-manipulation-pleuromutlin-gene-Alberti-2016.pdf

Heterocystless mutants ofAnabaenaPCC7120 with nitrogenase activity

Autor: William D. P. Stewart, David W. Spence

Publikováno v: FEMS Microbiology Letters. 40:119-122

Following NTG mutagenesis, four independent mutants of Anabaena PCC7120 defective in heterocyst differentiation were isolated. These fell into 2 distinct classes; (1) those unable to differentiate heterocysts or show whole-cell acetylene reduction ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::93f0ad3a25c54c37249f42514442cfa8
https://doi.org/10.1111/j.1574-6968.1987.tb01993.x