Zobrazeno 1 - 10
of 88
pro vyhledávání: '"David W Sanders"'
Autor:
Valerie Ann Perez, David W Sanders, Ayde Mendoza-Oliva, Barbara Elena Stopschinski, Vishruth Mullapudi, Charles L White, Lukasz A Joachimiak, Marc I Diamond
Publikováno v:
eLife, Vol 12 (2023)
Neurodegenerative tauopathies are caused by accumulation of toxic tau protein assemblies. This appears to involve template-based seeding events, whereby tau monomer changes conformation and is recruited to a growing aggregate. Several large families
Externí odkaz:
https://doaj.org/article/f2ba8704fa184b1ba71c0f45a6685787
Autor:
David W Sanders, Chanelle C Jumper, Paul J Ackerman, Dan Bracha, Anita Donlic, Hahn Kim, Devin Kenney, Ivan Castello-Serrano, Saori Suzuki, Tomokazu Tamura, Alexander H Tavares, Mohsan Saeed, Alex S Holehouse, Alexander Ploss, Ilya Levental, Florian Douam, Robert F Padera, Bruce D Levy, Clifford P Brangwynne
Publikováno v:
eLife, Vol 10 (2021)
Many enveloped viruses induce multinucleated cells (syncytia), reflective of membrane fusion events caused by the same machinery that underlies viral entry. These syncytia are thought to facilitate replication and evasion of the host immune response.
Externí odkaz:
https://doaj.org/article/a25f5d2a1fee480aabdd9b8491fcd288
Autor:
Patrick Qi Wang, Brynn P. Charron, Kalter Hali, Matthew Raleigh, Christopher Del Balso, Mark D. Macleod, David W. Sanders, Abdel-Rahman Lawendy
Publikováno v:
International Journal of Surgical Oncology, Vol 2024 (2024)
Background. As cancer survivorship continues to improve, the perioperative morbidity and mortality following surgical treatment of metastatic bone disease become an increasingly important consideration. The objective of this study is to identify risk
Externí odkaz:
https://doaj.org/article/b552746be02f489d82f120231beaa6f3
Autor:
Christopher Del Balso MBBS, MSc, Mansur M. Halai BSc (Hons), MBChB, Mark D. MacLeod MD, David W. Sanders MD, MSc, Abdel Rahman Lawendy MD, PhD
Publikováno v:
Foot & Ankle Orthopaedics, Vol 7 (2022)
Background: The safety of outpatient total ankle arthroplasty (TAA), and factors predictive of early complications are poorly understood. The objective of this study was to determine the frequency of early complications in patients undergoing outpati
Externí odkaz:
https://doaj.org/article/dd3bf6f929be473ba0e3462e2098fae4
Autor:
Daniel S. W. Lee, Chang-Hyun Choi, David W. Sanders, Lien Beckers, Joshua A. Riback, Clifford P. Brangwynne, Ned S. Wingreen
Publikováno v:
Nature Physics. 19:586-596
Phase separation of biomolecules into condensates has emerged as a mechanism for intracellular organization and affects many intracellular processes, including reaction pathways through the clustering of enzymes and pathway intermediates. Precise and
Autor:
Olawale A. Sogbein, David W. Sanders, Mark MacLeod, Christopher Del Balso, Abdel-Rahman Lawendy, Jun Yi
Publikováno v:
Foot and Ankle Surgery. 28:720-725
Background Indications for deltoid ligament repair in bimalleolar equivalent ankle fractures are unclear. This study compared radiographic outcomes in bimalleolar equivalent ankle fractures undergoing open reduction internal fixation (ORIF) +/− del
Autor:
Valerie A. Perez, David W. Sanders, Ayde Mendoza-Oliva, Barbara E. Stopschinski, Vishruth Mullapudi, Charles L White, Lukasz A. Joachimiak, Marc I. Diamond
Publikováno v:
bioRxiv
Neurodegenerative tauopathies are caused by accumulation of toxic tau protein assemblies. This appears to involve template-based seeding events, whereby tau monomer changes conformation and is recruited to a growing aggregate. Several large families
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a80b333d61b7f9a9e6fb3ff8cdb6476
https://doi.org/10.1101/2023.03.16.532880
https://doi.org/10.1101/2023.03.16.532880
Autor:
Itika Saha, Patricia Yuste-Checa, Miguel Da Silva Padilha, Qiang Guo, Roman Körner, Hauke Holthusen, Victoria A. Trinkaus, Irina Dudanova, Rubén Fernández-Busnadiego, Wolfgang Baumeister, David W. Sanders, Saurabh Gautam, Marc I. Diamond, F. Ulrich Hartl, Mark S. Hipp
Publikováno v:
Nature Communications, 14:560. Nature Publishing Group
Amyloid-like aggregates of the microtubule-associated protein Tau are associated with several neurodegenerative disorders including Alzheimer’s disease. The existence of cellular machinery for the removal of such aggregates has remained unclear, as
Autor:
Joseph Cavanagh, Christopher Del Balso, Veer Sohail Sidhu, Sahil Prabhnoor Sidhu, Emil H. Schemitsch, Yousif Atwan, David W. Sanders, Abdel Lawendy
Publikováno v:
Journal of Orthopaedic Trauma. 36:152-156
OBJECTIVES To investigate patient demographics, injury characteristics, radiographic outcomes, and identify risk factors for developing post-traumatic arthritis in high energy transsyndesmotic ankle fracture dislocations, or "Logsplitter" injuries. D
Publikováno v:
Evidence‐Based Orthopedics. :55-58