Zobrazeno 1 - 10
of 190
pro vyhledávání: '"David W Dunne"'
Autor:
Elias K Asuming-Brempong, Irene Ayi, William van der Puije, Ben A Gyan, Irene A Larbi, Yvonne Ashong, Naa Adjeley Frempong, Joseph K Quartey, Joseph Otchere, Frances M Jones, Shona Wilson, David W Dunne, Daniel A Boakye
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 3, p e0010115 (2022)
BackgroundEvidence from recent studies in Schistosoma mansoni-endemic areas show an age-associated immunity that is positively correlated with IgE titres to Schistosoma mansoni-specific tegumental allergen-like protein 1 (SmTAL1). The structural homo
Externí odkaz:
https://doaj.org/article/bca432a84c0e40dd859d8eb724d09dd0
Autor:
Humphrey D Mazigo, David W Dunne, Domenica Morona, Therese E Lutufyo, Safari M Kinung’hi, Geofrey Kaatano, Fred Nuwaha
Publikováno v:
Parasites & Vectors, Vol 8, Iss 1, Pp 1-13 (2015)
Abstract Background The pathogenesis of S. mansoni infection involves chronic inflammatory responses to parasite eggs which can be associated with a characteristic periportal fibrosis (PPF) and the progression to severe hepatosplenic disease. The eff
Externí odkaz:
https://doaj.org/article/959aea71de1149e7b8afb72a1d4f7a42
Autor:
Humphrey D Mazigo, David W Dunne, Shona Wilson, Safari M Kinung’hi, Angela Pinot de Moira, Frances M Jones, Domenica Morona, Fred Nuwaha
Publikováno v:
Parasites & Vectors, Vol 7, Iss 1, Pp 1-9 (2014)
Abstract Background Co-infection with S. mansoni and Human Immunodeficiency Virus-1 (HIV-1) has been described in sub-Saharan Africa. However, few community-based studies have been conducted to assess the association between the two diseases. The pre
Externí odkaz:
https://doaj.org/article/989a4128a5154a3c848504d2a39e0a9e
Autor:
Goylette F Chami, Alan Fenwick, Erwin Bulte, Andreas A Kontoleon, Narcis B Kabatereine, Edridah M Tukahebwa, David W Dunne
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 12, p e0004287 (2015)
Externí odkaz:
https://doaj.org/article/faa158402a4c43ce83ead02ed3325a46
Autor:
Nidhi Tyagi, Edward J Farnell, Colin M Fitzsimmons, Stephanie Ryan, Edridah Tukahebwa, Rick M Maizels, David W Dunne, Janet M Thornton, Nicholas Furnham
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 10, p e1004546 (2015)
Allergic reactions can be considered as maladaptive IgE immune responses towards environmental antigens. Intriguingly, these mechanisms are observed to be very similar to those implicated in the acquisition of an important degree of immunity against
Externí odkaz:
https://doaj.org/article/dd58467b718543aca24a62c32fee7896
Autor:
Goylette F Chami, Alan Fenwick, Erwin Bulte, Andreas A Kontoleon, Narcis B Kabatereine, Edridah M Tukahebwa, David W Dunne
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 10, p e0004193 (2015)
BACKGROUND:The association of anaemia with intestinal schistosomiasis and hookworm infections are poorly explored in populations that are not limited to children or pregnant women. METHODS:We sampled 1,832 individuals aged 5-90 years from 30 communit
Externí odkaz:
https://doaj.org/article/80469ecdce424eb69141ba0733c6aff1
Autor:
Iain W Chalmers, Colin M Fitzsimmons, Martha Brown, Christine Pierrot, Frances M Jones, Jakub M Wawrzyniak, Narcis Fernandez-Fuentes, Edridah M Tukahebwa, David W Dunne, Jamal Khalife, Karl F Hoffmann
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 7, p e0003920 (2015)
The heptalaminate-covered, syncytial tegument is an important anatomical adaptation that enables schistosome parasites to maintain long-term, intravascular residence in definitive hosts. Investigation of the proteins present in this surface layer and
Externí odkaz:
https://doaj.org/article/056ec1d94ebd4525a82f6f65d1703c45
Autor:
Daniel Wan, Fernanda Ludolf, Daniel G W Alanine, Owen Stretton, Eman Ali Ali, Nafal Al-Barwary, Xiaowei Wang, Michael J Doenhoff, Adriano Mari, Colin M Fitzsimmons, David W Dunne, Ryosuke Nakamura, Guilherme C Oliveira, Marcos J C Alcocer, Franco H Falcone
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 9, p e3124 (2014)
Parasite-specific IgE is thought to correlate with protection against Schistosoma mansoni infection or re-infection. Only a few molecular targets of the IgE response in S. mansoni infection have been characterised. A better insight into the basic mec
Externí odkaz:
https://doaj.org/article/6f1a2532c35a4c3c967e91d826f512e9
Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
The Th2 immune response, culminating in eosinophilia and IgE production, is not only characteristic of allergy but also of infection by parasitic worms (helminths). Anti-parasite IgE has been associated with immunity against a range of helminth infec
Externí odkaz:
https://doaj.org/article/d1d8f3ecfc374f6ab460db744f59c4f7
Autor:
Anna M Hoy, Rachel J Lundie, Alasdair Ivens, Juan F Quintana, Norman Nausch, Thorsten Forster, Frances Jones, Narcis B Kabatereine, David W Dunne, Francisca Mutapi, Andrew S Macdonald, Amy H Buck
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 2, p e2701 (2014)
MicroRNAs (miRNAs) are a class of short non-coding RNA that play important roles in disease processes in animals and are present in a highly stable cell-free form in body fluids. Here, we examine the capacity of host and parasite miRNAs to serve as t
Externí odkaz:
https://doaj.org/article/b794d4cab0984b058bee5ee827781f68