Zobrazeno 1 - 10
of 110
pro vyhledávání: '"David W, Schmidtke"'
Effects of Topography and PDGF on the Response of Corneal Keratocytes to Fibronectin-Coated Surfaces
Autor:
Kevin H. Lam, Tarik Z. Shihabeddin, Jacob A. Awkal, Alex M. Najjar, Miguel Miron-Mendoza, Daniel P. Maruri, Victor D. Varner, W. Matthew Petroll, David W. Schmidtke
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 4, p 217 (2023)
During corneal wound healing, corneal keratocytes are exposed to both biophysical and soluble cues that cause them to transform from a quiescent state to a repair phenotype. How keratocytes integrate these multiple cues simultaneously is not well und
Externí odkaz:
https://doaj.org/article/e883c5af1a8e435d83ab39f304bac3cc
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Following injury and refractive surgery, corneal wound healing can initiate a protracted fibrotic response that interferes with ocular function. This fibrosis is related, in part, to the myofibroblast differentiation of corneal keratocytes in respons
Externí odkaz:
https://doaj.org/article/b54775678df54c3da907717c08ab648a
Autor:
David W. Schmidtke, S. George, Douglas A. Horstmanshof, Hendra Setiadi, Aly El-Banayosy, James W. Long, Ahmed M. El-Banayosy
Publikováno v:
ASAIO journal (American Society for Artificial Internal Organs : 1992). 68(8)
Infection is a serious adverse event limiting left ventricular assist device (LVAD) therapy in advanced heart failure patients, but a reliable means to identify patients at increased risk of infection is still lacking. We hypothesized that preoperati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30688b09867e128780198a4827c9db18
https://pubmed.ncbi.nlm.nih.gov/34772849
https://pubmed.ncbi.nlm.nih.gov/34772849
Autor:
Jessica S. Hook, Mou Cao, Renee M. Potera, Nesreen Z. Alsmadi, David W. Schmidtke, Jessica G. Moreland
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The mortality rate of patients with critical illness has decreased significantly over the past two decades, but the rate of decline has slowed recently, with organ dysfunction as a major driver of morbidity and mortality. Among patients with the syst
Externí odkaz:
https://doaj.org/article/91f329ba697242c59baecb8d30612bf5
Publikováno v:
Biosensors and Bioelectronics. 235:115340
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab66a3916826afadff3091ff5d3837f8
https://doi.org/10.1016/j.bios.2023.115340
https://doi.org/10.1016/j.bios.2023.115340
Autor:
Rahul Atmaramani, Bryan J. Black, Kevin H. Lam, Vinit M. Sheth, Joseph J. Pancrazio, David W. Schmidtke, Nesreen Zoghoul Alsmadi
Publikováno v:
Micromachines, Vol 10, Iss 2, p 143 (2019)
In vitro systems comprised of wells interconnected by microchannels have emerged as a platform for the study of cell migration or multicellular models. In the present study, we systematically evaluated the effect of microchannel width on spontaneous
Externí odkaz:
https://doaj.org/article/db2f40ebdee1466f8c789034dde0df82
Autor:
Krithika S. Iyer, Daniel P. Maruri, Kara E. Peak, David W. Schmidtke, W. Matthew Petroll, Victor D. Varner
Publikováno v:
Exp Eye Res
During corneal wound healing, keratocytes present within the corneal stroma become activated into a repair phenotype upon the release of growth factors, such as transforming growth factor-beta 1 (TGF-β1) and platelet-derived growth factor-BB (PDGF-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5843c4ec27467cd0e15eb357ca9d3d
https://europepmc.org/articles/PMC10163834/
https://europepmc.org/articles/PMC10163834/
Autor:
Pouriska B. Kivanany, Kyle C. Grose, Nihan Yonet-Tanyeri, Sujal Manohar, Yukta Sunkara, Kevin H. Lam, David W. Schmidtke, Victor D. Varner, W. Matthew Petroll
Publikováno v:
Journal of Functional Biomaterials, Vol 9, Iss 4, p 54 (2018)
Background: Corneal stromal cells (keratocytes) are responsible for developing and maintaining normal corneal structure and transparency, and for repairing the tissue after injury. Corneal keratocytes reside between highly aligned collagen lamellae i
Externí odkaz:
https://doaj.org/article/828b333c5c1e4b398dacea8eda14098e
Autor:
Hendra Setiadi, Ahmed M. El Banayosy, David W. Schmidtke, David W. Vanhooser, Douglas A. Horstmanshof, Aly El Banayosy, James W. Long
Publikováno v:
ASAIO Journal. 68:45-45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74bca8a96cccd9090b870e4ef880b9b3
https://doi.org/10.1097/01.mat.0000840956.01937.11
https://doi.org/10.1097/01.mat.0000840956.01937.11
ECM Stiffness Controls the Activation and Contractility of Corneal Keratocytes in Response to TGF-β1
Autor:
Victor D. Varner, W. Matthew Petroll, Miguel Miron-Mendoza, David W. Schmidtke, Daniel P. Maruri, Pouriska B. Kivanany, Joshua M. Hack
Publikováno v:
Biophys J
After surgery or traumatic injury, corneal wound healing can cause a scarring response that stiffens the tissue and impairs ocular function. This fibrosis is caused in part by the activation of corneal keratocytes from a native mechanically quiescent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1014fd6a47aad94298aad00c3474fd60
https://europepmc.org/articles/PMC7677126/
https://europepmc.org/articles/PMC7677126/