Zobrazeno 1 - 10
of 81
pro vyhledávání: '"David W, Powell"'
Autor:
Timothy D. Cummins, David W. Powell, Daniel W. Wilkey, Makayla P. Brady, Frederick W. Benz, Michelle T. Barati, Dawn J. Caster, Jon B. Klein, Michael L. Merchant
Publikováno v:
Glomerular Diseases (2022)
Chronic kidney disease (CKD) affects 30 million adults, costs ~$79 billion dollars (2016) in Medicare expenditures, and is the ninth leading cause of death in the United States. The disease is silent or undiagnosed in almost half of people with sever
Externí odkaz:
https://doaj.org/article/8f18e4c242584b5897ec69031437d4a2
Publikováno v:
Lupus Science and Medicine, Vol 7, Iss 1 (2020)
SLE is a complex autoimmune disease with genetic, epigenetic, immune-regulatory, environmental and hormonal factors. Kidney inflammation and injury, termed lupus nephritis (LN), occurs in over half of patients with SLE and is a leading cause of disab
Externí odkaz:
https://doaj.org/article/1f1d81f1373b4c71ac736d6168f02be4
Autor:
Dawn J, Caster, David W, Powell
Publikováno v:
Lupus (Los Angeles). 6(1)
Lupus Nephritis (LN) is the leading cause of morbidity and mortality from Systemic Lupus Erythematosus (SLE) and enhanced activation of the transcription regulator nuclear factor kappa B (NF-κB) is implicated as a central player in the development a
Autor:
Shirong Zheng, Susan Coventry, Lu Cai, David W. Powell, Venkatakrishna R. Jala, Bodduluri Haribabu, Paul N. Epstein
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
In diabetic nephropathy (DN) proinflammatory chemokines and leukocyte infiltration correlate with tubulointerstitial injury and declining renal function. The atypical chemokine receptor ACKR2 is a chemokine scavenger receptor which binds and sequeste
Externí odkaz:
https://doaj.org/article/ab805f31a12c47e497baba9178aa7d45
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
Externí odkaz:
https://doaj.org/article/f637c8ac8c0b4cccad6a84cd738c6c8a
Autor:
Paul Dascani, Chuanlin Ding, David Tieri, Jun Yan, Xiaoying Lin, Justin T. Kos, Mingqian Zhou, Dawn J. Caster, David W. Powell, Corey T. Watson, Chengping Wen
Publikováno v:
J Immunol
Our previous work has revealed the ability of CD11b to regulate BCR signaling and control autoimmune disease in mice. However, how CD11b regulates the immune response under normal conditions remains unknown. Through the use of a CD11b knockout model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42013b16cf7ae7e07845dea5d7454083
https://europepmc.org/articles/PMC8455437/
https://europepmc.org/articles/PMC8455437/
Autor:
Susan Coventry, Michelle T. Barati, John B. Harley, Daniel W. Wilkey, Ami Joglekar, Dawn J. Caster, Erik A. Korte, Jessica Hata, Michael L. Merchant, David W. Powell, Brad H. Rovin, Bahram Namjou-Khales, Jon B. Klein, Kenneth R. McLeish
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 10, Iss 793, p 793 (2021)
Volume 10
Issue 4
Journal of Clinical Medicine, Vol 10, Iss 793, p 793 (2021)
Volume 10
Issue 4
Kidney involvement in systemic lupus erythematosus (SLE)—termed lupus nephritis (LN)—is a severe manifestation of SLE that can lead to end-stage kidney disease (ESKD). LN is characterized by immune complex deposition and inflammation in the glome
Autor:
Makayla P. Brady, Saiteja Chava, Shweta Tandon, Madhavi J. Rane, Michelle T. Barati, Dawn J. Caster, David W. Powell
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 11; Pages: 3199
Background: Lupus nephritis (LN) is a prevalent and severe complication of systemic lupus erythematosus (SLE). Non-invasive diagnostics are limited, and current therapies have inadequate response rates. Expression of the chemokine Interferon-γ-induc
Publikováno v:
Lupus Science & Medicine
Lupus Science and Medicine, Vol 7, Iss 1 (2020)
Lupus Science and Medicine, Vol 7, Iss 1 (2020)
SLE is a complex autoimmune disease with genetic, epigenetic, immune-regulatory, environmental and hormonal factors. Kidney inflammation and injury, termed lupus nephritis (LN), occurs in over half of patients with SLE and is a leading cause of disab
Publikováno v:
Translational Research. 201:26-39
Patients with systemic lupus erythematosus (SLE) frequently develop lupus nephritis (LN), a condition that can lead to end stage kidney disease (ESKD). Multiple serum and urine biomarkers for LN have been proposed in recent years, yet none have becom