Zobrazeno 1 - 10
of 57
pro vyhledávání: '"David W, Buchholz"'
Autor:
Siqi Gao, Alan T. Tang, Min Wang, David W. Buchholz, Brian Imbiakha, Jisheng Yang, Xiaowen Chen, Peter Hewins, Patricia Mericko-Ishizuka, N. Adrian Leu, Stephanie Sterling, Avery August, Kellie A. Jurado, Edward E. Morrisey, Hector Aguilar-Carreno, Mark L. Kahn
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Endothelial damage and vascular pathology have been recognized as major features of COVID-19 since the beginning of the pandemic. Two main theories regarding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) damages endothelial cells a
Externí odkaz:
https://doaj.org/article/e5d15a44eed14d9d8481a9fdb43d3196
Autor:
Duncan G. Ithinji, David W. Buchholz, Shahrzad Ezzatpour, I. Abrrey Monreal, Yu Cong, Julie Sahler, Amandip Singh Bangar, Brian Imbiakha, Viraj Upadhye, Janie Liang, Andrew Ma, Birgit Bradel-Tretheway, Benjamin Kaza, Yao Yu Yeo, Eun Jin Choi, Gunner P. Johnston, Louis Huzella, Erin Kollins, Saurabh Dixit, Shuiqing Yu, Elena Postnikova, Victoria Ortega, Avery August, Michael R. Holbrook, Hector C. Aguilar
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-14 (2022)
Abstract Experimental vaccines for the deadly zoonotic Nipah (NiV), Hendra (HeV), and Ebola (EBOV) viruses have focused on targeting individual viruses, although their geographical and bat reservoir host overlaps warrant creation of multivalent vacci
Externí odkaz:
https://doaj.org/article/de5f5906bdda428eae62711a3887d67e
Autor:
Alan T Tang, David W Buchholz, Katherine M Szigety, Brian Imbiakha, Siqi Gao, Maxwell Frankfurter, Min Wang, Jisheng Yang, Peter Hewins, Patricia Mericko-Ishizuka, N Adrian Leu, Stephanie Sterling, Isaac A Monreal, Julie Sahler, Avery August, Xuming Zhu, Kellie A Jurado, Mingang Xu, Edward E Morrisey, Sarah E Millar, Hector C Aguilar, Mark L Kahn
Publikováno v:
PLoS Biology, Vol 21, Iss 2, p e3001989 (2023)
Angiotensin-converting enzyme 2 (ACE2) is the cell-surface receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). While its central role in Coronavirus Disease 2019 (COVID-19) pathogenesis is indisputable, there remains significan
Externí odkaz:
https://doaj.org/article/1b38b8dd914148c090723f094f8d38fc
Autor:
Karen N. Barnard, Brian R. Wasik, Justin R. LaClair, David W. Buchholz, Wendy S. Weichert, Brynn K. Alford-Lawrence, Hector C. Aguilar, Colin R. Parrish
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT Sialic acids (Sia) are widely displayed on the surfaces of cells and tissues. Sia come in a variety of chemically modified forms, including those with acetyl modifications at the C-7, C-8, and C-9 positions. Here, we analyzed the distributio
Externí odkaz:
https://doaj.org/article/10495cbe41924e2897777e5e6ce12eeb
Autor:
Amandine Gamble, Yao Yu Yeo, Aubrey A. Butler, Hubert Tang, Celine E. Snedden, Christian T. Mason, David W. Buchholz, John Bingham, Hector C. Aguilar, James O. Lloyd-Smith
Publikováno v:
Viruses, Vol 13, Iss 9, p 1755 (2021)
Syncytium formation, i.e., cell–cell fusion resulting in the formation of multinucleated cells, is a hallmark of infection by paramyxoviruses and other pathogenic viruses. This natural mechanism has historically been a diagnostic marker for paramyx
Externí odkaz:
https://doaj.org/article/0522a001a50f4d1a8934eb9412ab0237
Autor:
Aaron T. Hendricksen, Shahrzad Ezzatpour, Anunay J. Pulukuri, Austin T. Ryan, Tatum J. Flanagan, William Frantz, David W. Buchholz, Victoria Ortega, Isaac A. Monreal, Julie M. Sahler, Amy E. Nielsen, Hector C. Aguilar, Rock J. Mancini
Publikováno v:
Advanced Healthcare Materials.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba1f241a01ce212fc0fe9b60156df441
https://doi.org/10.1002/adhm.202202918
https://doi.org/10.1002/adhm.202202918
Autor:
Tirosh Shapira, I. Abrrey Monreal, Sébastien P. Dion, David W. Buchholz, Brian Imbiakha, Andrea D. Olmstead, Mason Jager, Antoine Désilets, Guang Gao, Mathias Martins, Thierry Vandal, Connor A. H. Thompson, Aaleigha Chin, William D. Rees, Theodore Steiner, Ivan Robert Nabi, Eric Marsault, Julie Sahler, Diego G. Diel, Gerlinde R. Van de Walle, Avery August, Gary R. Whittaker, Pierre-Luc Boudreault, Richard Leduc, Hector C. Aguilar, François Jean
Publikováno v:
Nature. 605:340-348
The COVID-19 pandemic caused by the SARS-CoV-2 virus remains a global public health crisis. Although widespread vaccination campaigns are underway, their efficacy is reduced owing to emerging variants of concern1,2. Development of host-directed thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9dca545d7fbe19dcbebd61e81a4589
https://doi.org/10.1038/s41586-022-04661-w
https://doi.org/10.1038/s41586-022-04661-w
Autor:
Alan T. Tang, David W. Buchholz, Katherine M. Szigety, Brian Imbhiaka, Siqi Gao, Maxwell Frankfurter, Min Wang, Jisheng Yang, Peter Hewins, Patricia Mericko-Ishizuka, N Adrian Leu, Stephanie Sterling, Isaac A. Monreal, Julie Sahler, Avery August, Xuming Zhu, Kellie A. Jurado, Mingang Xu, Edward E. Morrisey, Sarah E. Millar, Hector C. Aguilar, Mark L. Kahn
Publikováno v:
bioRxiv
Lethal COVID-19 is associated with respiratory failure that is thought to be caused by acute respiratory distress syndrome (ARDS) secondary to pulmonary infection. To date, the cellular pathogenesis has been inferred from studies describing the expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a6bb5badd4c5bf2d71b6c97b485e80
https://pubmed.ncbi.nlm.nih.gov/34909769
https://pubmed.ncbi.nlm.nih.gov/34909769
Autor:
Peter J. Hudson, Nita Bharti, Alison J. Peel, Lauren Dee, Olivier Restif, Cara E. Brook, Elinor Jax, Christina L. Faust, Clifton D. McKee, Colin R. Parrish, Tamika Lunn, James O. Lloyd-Smith, Aaron Morris, Claude Kwe Yinda, Amandine Gamble, Julia R Port, Yao Yu Yeo, Hector C. Aguilar, Raina K. Plowright, Daniel E. Crowley, Vincent J. Munster, David W. Buchholz, Emily S. Gurley, Tony Schountz, Caylee A. Falvo, Devin N. Jones, Maureen K. Kessler, Manuel Ruiz-Aravena, Celine E. Snedden
Publikováno v:
Nature Reviews. Microbiology
In the past two decades, three coronaviruses with ancestral origins in bats have emerged and caused widespread outbreaks in humans, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since the first SARS epidemic in 2002–2003,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33135571a2fe58693859eb1d04b31a0d
https://www.repository.cam.ac.uk/handle/1810/331060
https://www.repository.cam.ac.uk/handle/1810/331060
Publikováno v:
J Virol
Cedar virus (CedV) is a nonpathogenic member of the Henipavirus (HNV) genus of emerging viruses, which includes the deadly Nipah (NiV) and Hendra (HeV) viruses. CedV forms syncytia, a hallmark of henipaviral and paramyxoviral infections and pathogeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d75774d65cf190c0cb84cdcc358453d5
https://doi.org/10.1128/jvi.00666-21
https://doi.org/10.1128/jvi.00666-21