Zobrazeno 1 - 10
of 65
pro vyhledávání: '"David Vremec"'
Autor:
Silvia A Fuertes Marraco, Clare L Scott, Philippe Bouillet, Annette Ives, Slavica Masina, David Vremec, Elisa S Jansen, Lorraine A O'Reilly, Pascal Schneider, Nicolas Fasel, Ken Shortman, Andreas Strasser, Hans Acha-Orbea
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20189 (2011)
BackgroundDC are activated by pathogen-associated molecular patterns (PAMPs), and this is pivotal for the induction of adaptive immune responses. Thereafter, the clearance of activated DC is crucial to prevent immune pathology. While PAMPs are of maj
Externí odkaz:
https://doaj.org/article/b56d3e79d01545d096a0a06502ed8744
Autor:
Erinna F. Lee, W. Douglas Fairlie, David M. Tarlinton, Stephanie Grabow, Eleonora Ottina, Philippe Bouillet, Priscilla Soo, Cody C. Allison, Andreas Strasser, Yifan Zhan, Ingela B Vikstrom, Andrew M. Lew, Jamie L. Brady, Marco J Herold, David Vremec, David C.S. Huang, Jian-Guo Zhang, Emma M. Carrington, Marc Pellegrini, Robyn M. Sutherland
Publikováno v:
Proceedings of the National Academy of Sciences. 112:4044-4049
Dendritic cells (DCs) are heterogeneous, comprising subsets with functional specializations that play distinct roles in immunity as well as immunopathology. We investigated the molecular control of cell survival of two main DC subsets: plasmacytoid D
Autor:
Yifan Zhan, Andrew M. Lew, Li Wu, Shereen Oon, Ingela B Vikstrom, Jian-Guo Zhang, Ian P. Wicks, Emma M. Carrington, Phillipe Bouillet, Hyun-Ja Ko, Jamie L. Brady, Eric F Morand, David Vremec, Andreas Strasser, David C.S. Huang
Publikováno v:
Arthritis & Rheumatology. 67:797-808
Objective Interferon-α (IFNα)–producing plasmacytoid dendritic cells (PDCs) are implicated in the pathogenesis of systemic lupus erythematosus (SLE). IFNα-related genes are highlighted among SLE susceptibility alleles and are characteristically
Autor:
Wallace Y. Langdon, Ken Shortman, Shalin H. Naik, Nicholas D. Huntington, Donald Metcalf, Priyanka Sathe, David Vremec, Li Wu
Publikováno v:
Immunity. 41(1):104-115
SummaryThe relationship between dendritic cells (DCs) and macrophages is often debated. Here we ask whether steady-state, lymphoid-tissue-resident conventional DCs (cDCs), plasmacytoid DCs (pDCs), and macrophages share a common macrophage-DC-restrict
Publikováno v:
Blood. 121:11-19
The developmental origin of IFN-producing plasmacytoid dendritic cells (pDCs) has been uncertain. In the present study, we tracked the development of pDCs in cultures of BM precursors stimulated with Flt3 ligand. Common myeloid precursors (CMPs) prod
Autor:
David, Vremec
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1423
Dendritic cells (DCs) form a complex network of cells that initiate and orchestrate immune responses against a vast array of pathogenic challenges. Developmentally and functionally distinct DC subtypes differentially regulate T-cell function. Importa
Autor:
David Vremec
Publikováno v:
Methods in Molecular Biology ISBN: 9781493936045
Dendritic cells (DCs) form a complex network of cells that initiate and orchestrate immune responses against a vast array of pathogenic challenges. Developmentally and functionally distinct DC subtypes differentially regulate T-cell function. Importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7dc79650a9021d4c792507d42879627
https://doi.org/10.1007/978-1-4939-3606-9_5
https://doi.org/10.1007/978-1-4939-3606-9_5
Autor:
David Vremec, Kenneth M. Murphy, Mireille H. Lahoud, Ken Shortman, Fatma Ahmet, Irina Caminschi, Jose A Villadangos, William R. Heath
Publikováno v:
Molecular Immunology. 50:9-17
Injection of antigens coupled to antibodies against the dendritic cell (DC) surface molecule Clec9A has been shown to produce strongly enhanced antibody responses even without co-administration of adjuvants, via antigen presentation by DC on MHC clas
Autor:
Wei Shi, Chin-Nien Lee, Irina Caminschi, Susie Kitsoulis, Scott N. Mueller, Andrew M. Lew, Ken Shortman, Soo San Wan, Gordon K. Smyth, David Vremec, Fatma Ahmet, Belinda Phipson, Yu Kato, Mireille H. Lahoud, Gayle M. Davey, William R. Heath
Publikováno v:
The Journal of Immunology. 187:842-850
Three surface molecules of mouse CD8+ dendritic cells (DCs), also found on the equivalent human DC subpopulation, were compared as targets for Ab-mediated delivery of Ags, a developing strategy for vaccination. For the production of cytotoxic T cells
Autor:
David Vremec, Stuart I. Mannering, Leonard C. Harrison, Thomas Loudovaris, Ken Shortman, Anna I Proietto, Li Wu, Diana Mittag
Publikováno v:
The Journal of Immunology. 186:6207-6217
Mouse dendritic cells (DC) have been extensively studied in various tissues, especially spleen, and they comprise subsets with distinct developmental origins, surface phenotypes, and functions. Considerably less is known about human DC due to their r