Zobrazeno 1 - 10
of 16
pro vyhledávání: '"David Vetterlein"'
Autor:
Greg S. Blank, Monika B. Schoenhoff, Beth Hutchins, David Vetterlein, James D. Green, Daniel Maneval, Joyce Mordenti
Publikováno v:
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society.
Pharmacokinetic modeling can be a valuable tool In the development of potential therapeutics. To Illustrate its use In evaluating dosing regimens, an example with monoclonal antibodies (MAb) directed against the extracellular domain of the protooncog
Autor:
Charles Eigenbrot, Paul Carter, Leonard G. Presta, James H. Bourell, Mark P. O'Connell, Michael Covarrubias, David Vetterlein, Brad Snedecor, Robert F. Kelley
Publikováno v:
Biochemistry. 31(24)
The murine monoclonal antibody 4D5 (anti-p185HER2) inhibits the proliferation of human tumor cells overexpressing p185HER2 in vitro and has been "humanized" [Carter, P., Presta, L., Gorman, C. M., Ridgway, J. B. B., Henner, D., Wong, W.-L. T., Rowlan
Autor:
David Vetterlein, Gregory S. Blank
Publikováno v:
Analytical biochemistry. 190(2)
High-performance liquid affinity chromatography (HPLAC) utilizing Protein G as a ligand has been evaluated for rapid quantification of monoclonal antibodies (MAbs) in various solutions. The results obtained by HPLAC agreed to within 10% of a standard
Publikováno v:
Journal of immunological methods. 132(1)
The HER2/neu proto-oncogene encodes a receptor that belong to the tyrosine-specific protein kinase family. Amplification of the HER2 gene in patients with breast and ovarian cancer has been shown to predict poorer survival rates. In order to understa
Autor:
David Vetterlein, Hung Nguyen, Charles V. Benton, Jerome E. Groopman, John R. Bell, Daniel J. Capon, Donald Dowbenko, Laurence A. Lasky
Publikováno v:
Proceedings of the National Academy of Sciences. 82:7748-7752
A retrovirus [lymphoadenopathy-associated virus, human T-cell leukemia virus type III, acquired immunodeficiency syndrome (AIDS)-related virus] suspected of causing AIDS has been isolated recently. The detection of exposure to this retrovirus in dono
Autor:
David Vetterlein, Marvin Cassman
Publikováno v:
Biochemistry. 13:3243-3250
Autor:
David Vetterlein, Catherine Lucas, M.L. Peterson, S. Frie, Anthony Chen, Tim Gregory, C. Nelson
Publikováno v:
Journal of Immunological Methods. 113:113-122
Two immunoassays have been developed for the quantitation of part-per-million levels of contaminants likely to co-purify with monoclonal antibodies produced in tissue culture and purified by protein A affinity chromatography. These contaminants are b
Publikováno v:
FEBS Letters. (2):181-184
Autor:
Gary J. Calton, David Vetterlein
Publikováno v:
Annals of the New York Academy of Sciences. 413:294-296
Des anticorps monoclonaux anti-chaine legere de l'urokinase ont ete immobilises et utilises en tant que systeme modele pour montrer l'utilite de la purification par affinite. L'urokinase a ete isolee directement a partir d'urine humaine, de liquides