Zobrazeno 1 - 10
of 18
pro vyhledávání: '"David V. Thompson"'
Autor:
David V. Thompson, James J. Cali, Julia Gilden, Dan Lazar, Kevin Kupcho, Martha O'brien, Kevin Hsiao, Casey A. Sondgeroth
Publikováno v:
Cancer Research. 80:5595-5595
Cytokines play a major role in cancer biology as inflammatory and immunomodulatory agents and are frequently measured in cell culture models and other biological samples. Various methods are available for in vitro measurement of cytokines, but they t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e504c49ede06260447e149935e3ba12f
https://doi.org/10.1158/1538-7445.am2020-5595
https://doi.org/10.1158/1538-7445.am2020-5595
Autor:
Dan F Lazar, Kevin R Kupcho, Casey A Sondgeroth, Kevin Hsiao, David V Thompson, Martha A O’Brien, Julia K Gilden, James J Cali
Publikováno v:
The Journal of Immunology. 204:59.31-59.31
We have utilized NanoLuc® Binary Technology (NanoBiT®) to develop a homogeneous and rapid assay method (≤ 70 min completion time) to measure cytokines released from cells in culture without the need for sample transfer and requiring only a standa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d69bc05ed9c5da1f38ab05298ab1c73c
https://doi.org/10.4049/jimmunol.204.supp.59.31
https://doi.org/10.4049/jimmunol.204.supp.59.31
Publikováno v:
Springer Protocols Handbooks ISBN: 9781607612919
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adfd4bb4fc99d86865c03e22def683bb
https://doi.org/10.1007/978-1-60761-292-6_7
https://doi.org/10.1007/978-1-60761-292-6_7
Publikováno v:
Journal of biomolecular screening. 13(8)
A major focus in the current discovery of drugs targeting nuclear receptors (NRs) is identifying drugs with reduced side effects by improving selectivity, not only from other receptors but also by selective modulation of the NR of interest. Cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d97e3b1d1959a97fa887c4a0ad22479
https://pubmed.ncbi.nlm.nih.gov/18753690
https://pubmed.ncbi.nlm.nih.gov/18753690
Autor:
Maya Fuerstenau-Sharp, David R. Piper, Steve Duff, Stephen D. Hess, Pam Whitney, Mohammed Saleh Shekhani, C. Jachec, W. Jack Frazee, Hildegard C. Eliason, Kurt W. Vogel, Bryan D. Marks, Elizabeth A. Frey, Brian A. Pollok, David V. Thompson
Publikováno v:
Assay and drug development technologies. 6(2)
The life-threatening consequences of acquired, or drug-induced, long QT syndrome due to block of the human ether-a-go-go-related gene (hERG) channel are well appreciated and have been the cause of several drugs being removed from the market in recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70cebf6643f4d2882c6f2b5a7fa437fa
https://pubmed.ncbi.nlm.nih.gov/18471075
https://pubmed.ncbi.nlm.nih.gov/18471075
Autor:
Amke den Dulk-Ras, Paul J. J. Hooykaas, Michael J. Maroney, Rob A. Schilperoort, Leo S. Melchers, Hanneke A. J. van Vuuren, David V. Thompson
Publikováno v:
Plant Molecular Biology. 14:249-259
Octopine and nopaline strains of Agrobacterium tumefaciens were found to differ in virulence on Nicotiana glauca. This difference is due to the absence of a functional virF locus, which is necessary for efficient tumorigenesis on N. glauca, from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32edd83d3d078a201101a283fb6c8dd
https://doi.org/10.1007/bf00018565
https://doi.org/10.1007/bf00018565
Publikováno v:
Journal of biomolecular screening. 9(5)
CYP2C9 is a genetically polymorphic human cytochrome P450 isozyme involved in the oxidative metabolism of many drugs, including nonsteroidal anti-inflammatory compounds. Individuals genotyped heterozygous or homozygous for CYP2C9 allelic variants hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862fd92097c809c3891ebcd39c7cf879
https://pubmed.ncbi.nlm.nih.gov/15296644
https://pubmed.ncbi.nlm.nih.gov/15296644
Autor:
Ken B. Idler, Paul J. J. Hooykaas, Leo S. Melchers, Alice Beijersbergen, Barbara Schrammeijer, David V. Thompson
Publikováno v:
Journal of experimental botany. 51(347)
The nucleotide sequence of 42 775 bp of the vir-region from the Agrobacterium tumefaciens octopine Ti plasmid pTi15955 is reported here. Although the nucleotide sequences of several parts of this region from this or closely related plasmids have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8e1af7d04cccd853c1c695f1705193
https://pubmed.ncbi.nlm.nih.gov/10948245
https://pubmed.ncbi.nlm.nih.gov/10948245
Autor:
David V. Thompson, Martin K. Lewis
Publikováno v:
Nucleic acids research. 18(12)
A novel plasmid vector pSELECT-1 is described which can be used for highly efficient site-directed in vitro mutagenesis. The mutagenesis method is based on the use of single-stranded DNA and two primers, one mutagenic primer and a second correction p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b28e9d1a221214992a6a28d526a847
https://pubmed.ncbi.nlm.nih.gov/2194159
https://pubmed.ncbi.nlm.nih.gov/2194159