Výsledky vyhledávání - "David V. Gold"

Supplementary Table S1 from Milatuzumab–SN-38 Conjugates for the Treatment of CD74+ Cancers

Autor: David M. Goldenberg, David V. Gold, Fatma Tat, Robert M. Sharkey, Thomas M. Cardillo, Serengulam V. Govindan

PDF file - 59 KB, Reversed-phase HPLC analyses of cathepsin B incubates and buffer control incubates of ME-CL2E-SN-38, pH 5, 37 degrees Celsius. Values represent % of applied product.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46356aa29535a12d317021217a23259f
https://doi.org/10.1158/1535-7163.22500250.v1

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Data from Milatuzumab–SN-38 Conjugates for the Treatment of CD74+ Cancers

Autor: David M. Goldenberg, David V. Gold, Fatma Tat, Robert M. Sharkey, Thomas M. Cardillo, Serengulam V. Govindan

CD74 is an attractive target for antibody–drug conjugates (ADC), because it internalizes and recycles after antibody binding. CD74 mostly is associated with hematologic tumors but is expressed also in solid cancers. Therefore, ADCs of the humanized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e648ecf567c521d924f6481502a382b
https://doi.org/10.1158/1535-7163.c.6536407.v1

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Data from A Novel Bispecific, Trivalent Antibody Construct for Targeting Pancreatic Carcinoma

Autor: Robert M. Sharkey, William J. McBride, Thomas M. Cardillo, Chien-Hsing Chang, Edmund A. Rossi, Habibe Karacay, David M. Goldenberg, David V. Gold

Preclinical and clinical studies have demonstrated the application of radiolabeled mAb-PAM4 for nuclear imaging and radioimmunotherapy of pancreatic carcinoma. We have now examined the ability of a novel PAM4-based, bispecific monoclonal antibody (mA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2528a321dcf165a17a67ee8be469b2d1
https://doi.org/10.1158/0008-5472.c.6496566.v1

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Akademický článek

Horizontal transmission of malignancy: in-vivo fusion of human lymphomas with hamster stroma produces tumors retaining human genes and lymphoid pathology.

Autor: David M Goldenberg, David V Gold, Meiyu Loo, Donglin Liu, Chien-Hsing Chang, Elaine S Jaffe

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e55324 (2013)

We report the in-vivo fusion of two Hodgkin lymphomas with golden hamster cheek pouch cells, resulting in serially-transplanted (over 5-6 years) GW-532 and GW-584 heterosynkaryon tumor cells displaying both human and hamster DNA (by FISH), lymphoma-l

Externí odkaz: https://doaj.org/article/030b31ac7b7647d382dcb8bed0191054

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Practical statistical considerations for investigating anti-tumor treatments in mice

Autor: Kim E. Zerba, David V. Gold, Lixin Lang

Publikováno v: Journal of Applied Statistics. 46:272-285

Anti-tumor treatment outcomes in mouse experiments can be challenging to interpret and communicate accurately. In reporting these experiments, rigorous statistical considerations are commonly absent, although statistical applications have been propos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::745508ac7d9f6ec6cc2e67e6a1d8ecca
https://doi.org/10.1080/02664763.2018.1477925

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A comparative study of PD-L1 IHC assays using immune cell scoring and CPS in breast cancer

Autor: Dimple Pandya, Jennifer Jones, Lloye M. Dillon, Mustimbo Roberts, Bin Li, Keyur Desai, David V. Gold

Publikováno v: Journal of Clinical Oncology. 38:e15262-e15262

e15262 Background: The clinical benefit of immune checkpoint inhibitors (ICIs) targeting the programmed death-1/programmed death ligand 1 (PD-L1) pathway has previously been demonstrated across a range of tumor types, including in PD-L1+ patients wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d13eff2ba7e38c379853df3b968f61c8
https://doi.org/10.1200/jco.2020.38.15_suppl.e15262

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