Zobrazeno 1 - 10
of 93
pro vyhledávání: '"David V. Cohn"'
Publikováno v:
Molecular and Cellular Biochemistry. 310:67-75
Polarized epithelial cells secrete proteins at either the apical or basolateral cell surface. A number of non-epithelial secretory proteins also exhibit polarized secretion when they are expressed in polarized epithelial cells but it is difficult to
Autor:
David V. Cohn, Birgit Grund, Fred M. Gordin, Abdel Babiker, Jennifer F Hoy, Wafaa El-Sadr, David A. Cooper, Jens D Lundgren, Janet Darbyshire, Brian Gazzard, Andrew N. Phillips, Jacquie Neuhaus, Karin L. Klingman, Dominic Abrams, James D. Neaton, Sean Emery, Calvin J. Cohen, M. H. Losso, Gerd Fätkenheuer, Norman Markowitz, Nathan Clumeck, William J. Burman, Roberto C. Arduino, Claire Rappoport
Publikováno v:
New England Journal of Medicine. 355:2283-2296
Despite declines in morbidity and mortality with the use of combination antiretroviral therapy, its effectiveness is limited by adverse events, problems with adherence, and resistance of the human immunodeficiency virus (HIV).We randomly assigned per
Publikováno v:
Regulatory Peptides. 103:53-58
Chromogranin A (CgA) is a glycoprotein stored in secretory granules of many endocrine and neuroendocrine cells. CgA undergoes tissue specific processing to release regulatory peptides. In the parathyroid, although processing is limited and variable,
Publikováno v:
Biochemical and Biophysical Research Communications. 270:631-636
Bovine chromogranin A (CgA), together with secreted alkaline phosphatase (SEAP) as an external control for apical secretion were expressed in MDCK cells to test if CgA contains sorting signals for polarized secretion. CgA, SEAP, and the endogenous ap
Autocrine inhibition of parathyroid cell secretion requires proteolytic processing of chromogranin A
Publikováno v:
Bone and Mineral. 17:323-333
Summary Chromogranin A (CgA, Secretory Protein-I) is a protein of about 450 amino acids representing a major soluble component of the secretory granules of parathyroid and other endocrine and neuroendocrine cells. In the parathyroid, CgA is costored
Publikováno v:
Regulatory Peptides. 34:25-32
The effects of porcine pancreastatin on insulin release stimulated by insulinotropic agents, glucagon, cholecystokinin-octapeptide (CCK-8), gastric inhibitory polypeptide (GIP) and L-arginine, were compared to those of bovine chromogranin A (CGA) usi
Publikováno v:
Journal of Biological Chemistry. 266:5780-5784
Chromogranin A (secretory protein-I) is an acidic sulfated glycoprotein found in secretory granules of most endocrine and neuroendocrine cells. In the parathyroid it is co-stored and secreted with parathormone in response to hypocalcemia. Differences
Publikováno v:
Endocrinology. 127:1329-1335
Chromogranin-A, also referred to as secretory protein-I, is a 50-kDa protein present in and secreted by most endocrine cells together with the native hormone. Porcine chro- mogranin-A contains a sequence identical to pancreastatin, sug- gesting that
Autor:
Sven Ulrik Gorr, David V. Cohn
Publikováno v:
Journal of Biological Chemistry. 265:3012-3016
Chromogranin A (secretory protein-I) is an acidic, sulfated glycoprotein found in secretory granules of most endocrine cells but not in exocrine or epithelial cells. Parathyroid chromogranin A is sulfated on tyrosine residues, whereas adrenal chromog
Publikováno v:
Peptides. 21(9)
Chromogranin A (CgA) is a glycoprotein present in secretory granules of endocrine cells. In the parathyroid, it is costored and cosecreted with parathormone (PTH) in response to hypocalcemia. CgA is the precursor of several bioactive peptides includi