Zobrazeno 1 - 10
of 10
pro vyhledávání: '"David V Rasicci"'
Autor:
David V Rasicci, Prince Tiwari, Skylar ML Bodt, Rohini Desetty, Fredrik R Sadler, Sivaraj Sivaramakrishnan, Roger Craig, Christopher M Yengo
Publikováno v:
eLife, Vol 11 (2022)
The auto-inhibited, super-relaxed (SRX) state of cardiac myosin is thought to be crucial for regulating contraction, relaxation, and energy conservation in the heart. We used single ATP turnover experiments to demonstrate that a dilated cardiomyopath
Externí odkaz:
https://doaj.org/article/2a972567fd55436c8074580ba6a5c3a8
Autor:
David V Rasicci, Prince Tiwari, Skylar ML Bodt, Rohini Desetty, Fredrik R Sadler, Sivaraj Sivaramakrishnan, Roger Craig, Christopher M Yengo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d666a9f4e73b507afa727aa42d6fe91
https://doi.org/10.7554/elife.77415.sa2
https://doi.org/10.7554/elife.77415.sa2
Autor:
Zabed Mahmud, Svetlana Tikunova, Natalya Belevych, Corey Wagg, Pavel Zhabyeyev, Philip B. Liu, David V. Rasicci, Richard Schulz, Christopher M. Yengo, Gavin Y. Oudit, Gary D. Lopaschuk, Peter J. Reiser, Jonathan P. Davis, Peter M. Hwang
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1147fd54b772479d3c37403d3f13bf41
https://doi.org/10.1096/fasebj.2022.36.s1.0r342
https://doi.org/10.1096/fasebj.2022.36.s1.0r342
Dissecting β-Cardiac Myosin and Cardiac Myosin-Binding Protein C Interactions using a Nanosurf Assay
Autor:
Anja M. Touma, Wanjian Tang, David V. Rasicci, Duha Vang, Ashim Rai, Samantha B. Previs, David M. Warshaw, Christopher M. Yengo, Sivaraj Sivaramakrishnan
Cardiac myosin-binding protein C (cMyBP-C) regulates cardiac contractility by slowing shortening velocity and sensitizing the thin filament to calcium. cMyBP-C has been shown to interact with the proximal myosin S2 tail and the thin filament. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff3eee6398032bbe628cb61e21e2b9c4
https://doi.org/10.1101/2022.03.11.483820
https://doi.org/10.1101/2022.03.11.483820
Publikováno v:
Biophysical Journal. 122:259a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3911a8f60d4ff8e99865efad2a5c2bd6
https://doi.org/10.1016/j.bpj.2022.11.1490
https://doi.org/10.1016/j.bpj.2022.11.1490
Impact of regulatory light chain mutation K104E on the ATPase and motor properties of cardiac myosin
Autor:
Christopher M. Yengo, Danuta Szczesna-Cordary, Neil B. Wood, Orville Kirkland, Kenneth S. Campbell, David V. Rasicci, Michael J. Previs, Faruk H. Moonschi, Jonathan F. Wenk
Publikováno v:
The Journal of General Physiology
Rasicci et al. investigate the mechanochemical properties of distinct isoforms of cardiac myosin carrying the K104E regulatory light chain mutation, previously associated with hypertrophic cardiomyopathy. They demonstrate that the mutation does not a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444ac6b72f3285f5272bc98a6d9101fa
https://doi.org/10.1085/jgp.202012811
https://doi.org/10.1085/jgp.202012811
Autor:
David V. Rasicci, Prince Tiwari, Rohini Desetty, Fredrik Sadler, Sivaraj Sivaramakrishnan, Roger W. Craig, Christopher M. Yengo
Publikováno v:
Biophysical Journal. 121:260a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c44c1cd20906aa3e90f2db29f6d99595
https://doi.org/10.1016/j.bpj.2021.11.1439
https://doi.org/10.1016/j.bpj.2021.11.1439
Autor:
David V. Rasicci, Jinghua Ge, Neil Wood, Gregory Milburn, Michael J. Previs, Kenneth S. Campbell, Christopher M. Yengo
Publikováno v:
Biophysical Journal. 121:106a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c722d544936fb202d30a6f22a2d096cb
https://doi.org/10.1016/j.bpj.2021.11.2176
https://doi.org/10.1016/j.bpj.2021.11.2176
Publikováno v:
Biophysical Journal. 118:425a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4395f8f83155a4bcce86792388a7accc
https://doi.org/10.1016/j.bpj.2019.11.2391
https://doi.org/10.1016/j.bpj.2019.11.2391
Autor:
Zabed Mahmud, Svetlana Tikunova, Natalya Belevych, Cory S. Wagg, Pavel Zhabyeyev, Philip B. Liu, David V. Rasicci, Christopher M. Yengo, Gavin Y. Oudit, Gary D. Lopaschuk, Peter J. Reiser, Jonathan P. Davis, Peter M. Hwang
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Small molecule cardiac troponin activators could potentially enhance cardiac muscle contraction in the treatment of systolic heart failure. We designed a small molecule, RPI-194, to bind cardiac/slow skeletal muscle troponin (Cardiac muscle and slow
Externí odkaz:
https://doaj.org/article/756603ce756d47d9bebb8a3a2a2a53cd