Zobrazeno 1 - 10
of 14
pro vyhledávání: '"David Vásquez-Velásquez"'
Autor:
Juan Andrades-Lagos, Javier Campanini-Salinas, Gianfranco Sabadini, Victor Andrade, Jaime Mella, David Vásquez-Velásquez
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1621 (2023)
According to the WHO, antimicrobial resistance is among the top 10 threats to global health. Due to increased resistance rates, an increase in the mortality and morbidity of patients has been observed, with projections of more than 10 million deaths
Externí odkaz:
https://doaj.org/article/75359a3bdc5a46348b44f4f6f7d7e1ca
Autor:
Juan Andrades-Lagos, Javier Campanini-Salinas, América Pedreros-Riquelme, Jaime Mella, Duane Choquesillo-Lazarte, P. P. Zamora, Hernán Pessoa-Mahana, Ian Burbulis, David Vásquez-Velásquez
Publikováno v:
Antibiotics, Vol 12, Iss 6, p 1065 (2023)
Resistance to antibacterial agents is a growing global public health problem that reduces the efficacy of available antibacterial agents, leading to increased patient mortality and morbidity. Unfortunately, only 16 antibacterial drugs have been appro
Externí odkaz:
https://doaj.org/article/25439a23b8eb439986ae4b0546dc7220
Autor:
Loreto Arrieta-Rodríguez, Daniela Espinoza-Rosales, Gonzalo Vera, Young Hwa Cho, David Cabezas, David Vásquez-Velásquez, Jaime Mella-Raipán, Carlos F. Lagos, Gonzalo Recabarren-Gajardo
Publikováno v:
Pharmaceuticals, Vol 14, Iss 6, p 528 (2021)
A new series of twenty-two C-5 substituted N-arylsulfonylindoles was prepared with the aim of exploring the influence of C-5 substitution on 5-HT6 receptor affinity. Eleven compounds showed moderate to high affinity at the receptor (Ki = 58–403 nM)
Externí odkaz:
https://doaj.org/article/1ab2e19e8e9c45508fb70a1c5c597cd3
Autor:
Javier Campanini-Salinas, Juan Andrades-Lagos, Nicolás Hinojosa, Fabián Moreno, Pedro Alarcón, Gerardo González-Rocha, Ian E. Burbulis, David Vásquez-Velásquez
Publikováno v:
Antibiotics, Vol 10, Iss 6, p 614 (2021)
There is an urgent need for the development of new antibiotics. Here, we describe the inhibitory activity of new quinone compounds against methicillin-resistant Staphylococcus aureus (ATCC® 43300), methicillin-sensitive S. aureus (ATCC® 29213), and
Externí odkaz:
https://doaj.org/article/cd9134ca73564c349fb7772d4d50cc22
Autor:
Javier Campanini-Salinas, Juan Andrades-Lagos, Gerardo Gonzalez Rocha, Duane Choquesillo-Lazarte, Soledad Bollo Dragnic, Mario Faúndez, Pedro Alarcón, Francisco Silva, Roberto Vidal, Edison Salas-Huenuleo, Marcelo Kogan, Jaime Mella, Gonzalo Recabarren Gajardo, David Vásquez-Velásquez
Publikováno v:
Molecules, Vol 23, Iss 7, p 1776 (2018)
A rapid emergence of resistant bacteria is occurring worldwide, endangering the efficacy of antibiotics and reducing the therapeutic arsenal available for treatment of infectious diseases. In the present study, we developed a new class of compounds w
Externí odkaz:
https://doaj.org/article/3d5bceafb92645069859d5a144ab502c
Autor:
Marcos Lorca, Cesar Morales-Verdejo, David Vásquez-Velásquez, Juan Andrades-Lagos, Javier Campanini-Salinas, Jorge Soto-Delgado, Gonzalo Recabarren-Gajardo, Jaime Mella
Publikováno v:
Molecules, Vol 23, Iss 5, p 1191 (2018)
The wide tissue distribution of the adrenergic β3 receptor makes it a potential target for the treatment of multiple pathologies such as diabetes, obesity, depression, overactive bladder (OAB), and cancer. Currently, there is only one drug on the ma
Externí odkaz:
https://doaj.org/article/6c9524049b044b0d840c91e7b143b7af
Autor:
Juan Andrades-Lagos, Ian E. Burbulis, Javier Campanini-Salinas, Gerardo González-Rocha, Pedro Alarcón, Nicolás Hinojosa, Fabián Moreno, David Vásquez-Velásquez
Publikováno v:
Antibiotics
Volume 10
Issue 6
Antibiotics, Vol 10, Iss 614, p 614 (2021)
Volume 10
Issue 6
Antibiotics, Vol 10, Iss 614, p 614 (2021)
There is an urgent need for the development of new antibiotics. Here, we describe the inhibitory activity of new quinone compounds against methicillin-resistant Staphylococcus aureus (ATCC® 43300), methicillin-sensitive S. aureus (ATCC® 29213), and
Autor:
David Cabezas, Jaime Mella-Raipán, Loreto Arrieta-Rodríguez, Young Hwa Cho, Carlos F. Lagos, Gonzalo Vera, Gonzalo Recabarren-Gajardo, David Vásquez-Velásquez, Daniela Espinoza-Rosales
Publikováno v:
Pharmaceuticals
Pharmaceuticals, Vol 14, Iss 528, p 528 (2021)
Volume 14
Issue 6
Pharmaceuticals, Vol 14, Iss 528, p 528 (2021)
Volume 14
Issue 6
A new series of twenty-two C-5 substituted N-arylsulfonylindoles was prepared with the aim of exploring the influence of C-5 substitution on 5-HT6 receptor affinity. Eleven compounds showed moderate to high affinity at the receptor (Ki = 58–403 nM)
Autor:
David Vásquez-Velásquez, Javier Campanini-Salinas, Olga L. Cifuentes-Vaca, Juan Andrades-Lagos, Antonio Laguna, M. Concepción Gimeno
Publikováno v:
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
By reaction of 2-aminofluorene with 2-pyridinecarboxaldehyde a new Schiff base (L) is obtained. The reaction of this ligand with Ag(I) and Cu(I) salts in different stoichiometry leads to the complexes [Ag(CF3SO3)(L)PPh3] (1) or [ML2]A (M = Ag, Cu; A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ca18654710836ad95102f9782778e0
http://zaguan.unizar.es/record/88161
http://zaguan.unizar.es/record/88161
Publikováno v:
Current Topics in Medicinal Chemistry. 18:1188-1202
Bacterial resistance is a growing problem worldwide and is estimated that deaths by infectious diseases associated with resistant pathogens will generate 10 million deaths per year in 2050. This problem becomes more serious due to the low level of re