Zobrazeno 1 - 10
of 75
pro vyhledávání: '"David Uehling"'
Autor:
Maria I. Edilova, Jaclyn C. Law, Safoura Zangiabadi, Kenneth Ting, Achire N. Mbanwi, Andrea Arruda, David Uehling, Methvin Isaac, Michael Prakesch, Rima Al-awar, Mark D. Minden, Ali A. Abdul-Sater, Tania H. Watts
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
TRAF1 is a pro-survival adaptor molecule in TNFR superfamily (TNFRSF) signaling. TRAF1 is overexpressed in many B cell cancers including refractory chronic lymphocytic leukemia (CLL). Little has been done to assess the role of TRAF1 in human cancer.
Externí odkaz:
https://doaj.org/article/b522459ea1914c9fb7a753c1f3981273
Autor:
Jeff C Liu, Veronique Voisin, Sharon Wang, Dong‐Yu Wang, Robert A Jones, Alessandro Datti, David Uehling, Rima Al‐awar, Sean E Egan, Gary D Bader, Ming Tsao, Tak W Mak, Eldad Zacksenhaus
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 12, Pp 1542-1560 (2014)
Abstract The tumor suppressors Pten and p53 are frequently lost in breast cancer, yet the consequences of their combined inactivation are poorly understood. Here, we show that mammary‐specific deletion of Pten via WAP‐Cre, which targets alveolar
Externí odkaz:
https://doaj.org/article/1740747192ac46058246e34663ff888d
Autor:
Anthony M. Joshua, Bradly G. Wouters, Amina Zoubeidi, Martin Gleave, Johann S. de Bono, Samantha Oakes, Marianne Koritzinsky, Bruce Montgomery, Housheng Hansen He, Antje Neeb, Bora Gurel, David Uehling, Haiyang Guo, Joan Sweet, Aleksandra Pesic, Zvi Shalev, Amanda Mawson, Richard Marcellus, Ines Figueiredo, Adam Sharp, Stefano Marastoni, Sujeeve Jeganathan, Yi Liang
Characterization of ENZ-resistant cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b8fcd7391f7e01b97b1abb9d017439
https://doi.org/10.1158/1078-0432.22484199.v1
https://doi.org/10.1158/1078-0432.22484199.v1
Autor:
Anthony M. Joshua, Bradly G. Wouters, Amina Zoubeidi, Martin Gleave, Johann S. de Bono, Samantha Oakes, Marianne Koritzinsky, Bruce Montgomery, Housheng Hansen He, Antje Neeb, Bora Gurel, David Uehling, Haiyang Guo, Joan Sweet, Aleksandra Pesic, Zvi Shalev, Amanda Mawson, Richard Marcellus, Ines Figueiredo, Adam Sharp, Stefano Marastoni, Sujeeve Jeganathan, Yi Liang
Clinical characteristics of prostate cancer patients with matched diagnostic (archival) castration-sensitive and metastatic castration-resistant tissue biopsies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0935884dec87a2cac187cbc329a9b4c9
https://doi.org/10.1158/1078-0432.22484169.v1
https://doi.org/10.1158/1078-0432.22484169.v1
Autor:
Donna L. Senger, Stephen M. Robbins, David R. Kaplan, J. Gregory Cairncross, Samuel Weiss, Artee Luchman, Jacob C. Easaw, Jeffrey L. Wrana, Alessandro Datti, David Uehling, Ahmed Aman, Xiuling Wang, Ngoc-Ha Dang, Xiaoguang Hao, Jennifer C. King, Natalie Grinshtein, J. Connor Wells, Xueqing Lun
Purpose: Glioblastoma is one of the most lethal cancers in humans, and with existing therapy, survival remains at 14.6 months. Current barriers to successful treatment include their infiltrative behavior, extensive tumor heterogeneity, and the presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352984f9333967436036ef5f69a99520
https://doi.org/10.1158/1078-0432.c.6523565.v1
https://doi.org/10.1158/1078-0432.c.6523565.v1
Autor:
Anthony M. Joshua, Bradly G. Wouters, Amina Zoubeidi, Martin Gleave, Johann S. de Bono, Samantha Oakes, Marianne Koritzinsky, Bruce Montgomery, Housheng Hansen He, Antje Neeb, Bora Gurel, David Uehling, Haiyang Guo, Joan Sweet, Aleksandra Pesic, Zvi Shalev, Amanda Mawson, Richard Marcellus, Ines Figueiredo, Adam Sharp, Stefano Marastoni, Sujeeve Jeganathan, Yi Liang
Purpose:Although enzalutamide (ENZ) has been widely used to treat de novo or castration-resistant metastatic prostate cancer, resistance develops and disease progression is ultimately inevitable. There are currently no approved targeted drugs to spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039924ac398c43af587dd28a6c3b0ffc
https://doi.org/10.1158/1078-0432.c.6531348
https://doi.org/10.1158/1078-0432.c.6531348
Autor:
Anthony M. Joshua, Bradly G. Wouters, Amina Zoubeidi, Martin Gleave, Johann S. de Bono, Samantha Oakes, Marianne Koritzinsky, Bruce Montgomery, Housheng Hansen He, Antje Neeb, Bora Gurel, David Uehling, Haiyang Guo, Joan Sweet, Aleksandra Pesic, Zvi Shalev, Amanda Mawson, Richard Marcellus, Ines Figueiredo, Adam Sharp, Stefano Marastoni, Sujeeve Jeganathan, Yi Liang
List of antibodies used for Western Blot analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d417f84a2eeefe0ab4c6e7c4f11de2ce
https://doi.org/10.1158/1078-0432.22484178.v1
https://doi.org/10.1158/1078-0432.22484178.v1
Autor:
Donna L. Senger, Stephen M. Robbins, David R. Kaplan, J. Gregory Cairncross, Samuel Weiss, Artee Luchman, Jacob C. Easaw, Jeffrey L. Wrana, Alessandro Datti, David Uehling, Ahmed Aman, Xiuling Wang, Ngoc-Ha Dang, Xiaoguang Hao, Jennifer C. King, Natalie Grinshtein, J. Connor Wells, Xueqing Lun
Figure S1: Preclinical assessment of clioquinol. Figure S2: Preclinical assessment of montelukast. Figure S3: Secondary validation of compounds identified via HTS. Figure S4: Sensitivity of BTICs to TMZ. Figure S5: Copper is required for Disulfiram-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c1d45a5657bc581427aa74a1e03623
https://doi.org/10.1158/1078-0432.22457381.v1
https://doi.org/10.1158/1078-0432.22457381.v1
Autor:
Anthony M. Joshua, Bradly G. Wouters, Amina Zoubeidi, Martin Gleave, Johann S. de Bono, Samantha Oakes, Marianne Koritzinsky, Bruce Montgomery, Housheng Hansen He, Antje Neeb, Bora Gurel, David Uehling, Haiyang Guo, Joan Sweet, Aleksandra Pesic, Zvi Shalev, Amanda Mawson, Richard Marcellus, Ines Figueiredo, Adam Sharp, Stefano Marastoni, Sujeeve Jeganathan, Yi Liang
Compound full list of two libraries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90fbcdc3dfdc4438d086e14ee0c7b4e7
https://doi.org/10.1158/1078-0432.22484172
https://doi.org/10.1158/1078-0432.22484172
Autor:
Anthony M. Joshua, Bradly G. Wouters, Amina Zoubeidi, Martin Gleave, Johann S. de Bono, Samantha Oakes, Marianne Koritzinsky, Bruce Montgomery, Housheng Hansen He, Antje Neeb, Bora Gurel, David Uehling, Haiyang Guo, Joan Sweet, Aleksandra Pesic, Zvi Shalev, Amanda Mawson, Richard Marcellus, Ines Figueiredo, Adam Sharp, Stefano Marastoni, Sujeeve Jeganathan, Yi Liang
List of primers used for qPCR analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873560933dcc19e69f39aac55ad587bc
https://doi.org/10.1158/1078-0432.22484175.v1
https://doi.org/10.1158/1078-0432.22484175.v1