Zobrazeno 1 - 10
of 18
pro vyhledávání: '"David Threadgill"'
Autor:
Aravindh Nagarajan, Kristin Scoggin, Jyotsana Gupta, Manuchehr Aminian, L Garry Adams, Michael Kirby, David Threadgill, Helene Andrews-Polymenis
Publikováno v:
PLoS Genetics, Vol 20, Iss 5, p e1011229 (2024)
Staphylococcus aureus (S. aureus) is an opportunistic pathogen causing diseases ranging from mild skin infections to life threatening conditions, including endocarditis, pneumonia, and sepsis. To identify host genes modulating this host-pathogen inte
Externí odkaz:
https://doaj.org/article/50315e75f7be410b9174f63ab5c73feb
Autor:
Hongying Wang, Zheng Shen, Chia-Shan Wu, Pengfei Ji, Ji Yeon Noh, Cédric G. Geoffroy, Sunja Kim, David Threadgill, Jianrong Li, Yu Zhou, Xiaoqiu Xiao, Hui Zheng, Yuxiang Sun
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Obesity is associated with chronic inflammation in the central nervous system (CNS), and neuroinflammation has been shown to have detrimental effects on mood and cognition. The growth hormone secretagogue receptor (GHSR), the biologically relevant re
Externí odkaz:
https://doaj.org/article/8fec41a6174d491db5c879b086c00aa4
Autor:
Xuying Zhang, Guanxi Xiao, Caroline Johnson, Yuheng Cai, Zachary K. Horowitz, Christine Mennicke, Robert Coffey, Mansoor Haider, David Threadgill, Rebecca Eliscu, Michael C. Oldham, Alon Greenbaum, H. Troy Ghashghaei
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106242- (2023)
Summary: The epidermal growth factor receptor (EGFR) plays a role in cell proliferation and differentiation during healthy development and tumor growth; however, its requirement for brain development remains unclear. Here we used a conditional mouse
Externí odkaz:
https://doaj.org/article/009e161e25ab4ba485fffac48cf84c13
Autor:
Srishtee Arora, Xiqi Li, Andrew Hillhouse, Kranti Konganti, Sara V. Little, Sara D. Lawhon, David Threadgill, Samuel Shelburne, Magnus Hook
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT Staphylococcus epidermidis is a leading cause of nosocomial infections in patients with a compromised immune system and/or an implanted medical device. Seventy to 90% of S. epidermidis clinical isolates are methicillin resistant and carry th
Externí odkaz:
https://doaj.org/article/760b86f90ce14c6f8e8842590cd24a8f
Autor:
Raine Lunde‐Young, Josue Ramirez, Vishal Naik, Marcus Orzabal, Jehoon Lee, Kranti Konganti, Andrew Hillhouse, David Threadgill, Jayanth Ramadoss
Publikováno v:
Brain and Behavior, Vol 9, Iss 7, Pp n/a-n/a (2019)
Abstract Introduction Prenatal alcohol exposure can contribute to fetal alcohol spectrum disorders (FASD), characterized by a myriad of developmental impairments affecting behavior and cognition. Studies show that many of these functional impairments
Externí odkaz:
https://doaj.org/article/fe6f625cc1154c7299d9b0224d0ac801
Autor:
Kenta Saito, Keisuke Horiuchi, Tokuhiro Kimura, Sakiko Mizuno, Masaki Yoda, Hideo Morioka, Haruhiko Akiyama, David Threadgill, Yasunori Okada, Yoshiaki Toyama, Kazuki Sato
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54853 (2013)
TNFα-converting enzyme (TACE) is a membrane-bound proteolytic enzyme with essential roles in the functional regulation of TNFα and epidermal growth factor receptor (EGFR) ligands. Previous studies have demonstrated critical roles for TACE in vivo,
Externí odkaz:
https://doaj.org/article/157398e933014c438e68b19babe1973d
Autor:
Marc Bissonnette, Alessandro Fichera, David Threadgill, John Hart, Hongyan Zhu, Loren Joseph, Jorge Delgado, Reba Mustafi, Sonia Cerda, Amikar Sehdev, Lata Aluri, Shamiram Badal, Ummuhan Tekin, Masha Kocherginsky, Ieva Taylor, Dario Cerasi, Urszula Dougherty
Purpose: Colon cancer is a major cause of cancer deaths. Dietary factors contribute substantially to the risk of this malignancy. Western-style diets promote development of azoxymethane-induced colon cancer. Although we showed that epidermal growth f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9872faf8f1444e9b16f8ce7b85140421
https://doi.org/10.1158/1078-0432.c.6517894
https://doi.org/10.1158/1078-0432.c.6517894
Autor:
Marc Bissonnette, Alessandro Fichera, David Threadgill, John Hart, Hongyan Zhu, Loren Joseph, Jorge Delgado, Reba Mustafi, Sonia Cerda, Amikar Sehdev, Lata Aluri, Shamiram Badal, Ummuhan Tekin, Masha Kocherginsky, Ieva Taylor, Dario Cerasi, Urszula Dougherty
Supplementary Data from Epidermal Growth Factor Receptor Is Required for Colonic Tumor Promotion by Dietary Fat in the Azoxymethane/Dextran Sulfate Sodium Model: Roles of Transforming Growth Factor- and PTGS2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a91dca136db4e4e9a257ce0bead9b6
https://doi.org/10.1158/1078-0432.22440592.v1
https://doi.org/10.1158/1078-0432.22440592.v1
Publikováno v:
Environ Sci Pollut Res Int
Lead (Pb) poisoning is a major public health concern in environmental justice communities of the USA and in many developing countries. There is no identified safety threshold for lead in blood, as low-level Pb exposures can lead to severe toxicity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc0dadaa427da306a181097ba991612
https://doi.org/10.1007/s11356-022-19333-5
https://doi.org/10.1007/s11356-022-19333-5
Autor:
Hui Yan, Wanbao Yang, Fenghua Zhou, Quan Pan, Kimberly Allred, Clinton Allred, Yuxiang Sun, David Threadgill, David Dostal, Carl Tong, Shaodong Guo
Publikováno v:
Circ Heart Fail
Background: Type 2 diabetes (T2D) is a high-risk factor for incident of cardiovascular diseases. Women at young ages show a reduced incidence of both T2D and cardiovascular diseases compared with men, but these disparities disappear in postmenopausal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72171112b947ac49112e2a01d6b18c06
https://doi.org/10.1161/circheartfailure.121.008758
https://doi.org/10.1161/circheartfailure.121.008758