Zobrazeno 1 - 10
of 14
pro vyhledávání: '"David Tes"'
Autor:
Claire Keun Sun Park, Tiana Trumpour, Amal Aziz, Jeffrey Scott Bax, David Tessier, Lori Gardi, Aaron Fenster
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Breast cancer screening has substantially reduced mortality across screening populations. However, a clinical need persists for more accessible, cost-effective, and robust approaches for increased-risk and diverse patient populations, especi
Externí odkaz:
https://doaj.org/article/05fe86852a7741a3acd336ced71e2a2a
Autor:
Ruolun Qiu, Kari Fonseca, Arthur Bergman, Jian Lin, David Tess, Lauren Newman, Alia Fahmy, Zivile Useckaite, Andrew Rowland, Manoli Vourvahis, David Rodrigues
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 1, Pp n/a-n/a (2024)
Abstract PF‐06835919, a ketohexokinase inhibitor, presented as an inducer of cytochrome P450 3A4 (CYP3A4) in vitro (human primary hepatocytes), and static mechanistic modeling exercises predicted significant induction in vivo (oral midazolam area u
Externí odkaz:
https://doaj.org/article/c423c1f6a91d4bdeba240e6d4515a168
Autor:
David Tes, Karl Kratkiewicz, Ahmed Aber, Luke Horton, Mohsin Zafar, Nour Arafat, Afreen Fatima, Mohammad RN Avanaki
Publikováno v:
Biomedical Engineering and Computational Biology, Vol 9 (2018)
Alzheimer disease is the most common form of dementia, affecting more than 5 million people in the United States. During the progression of Alzheimer disease, a particular protein begins to accumulate in the brain and also in extensions of the brain,
Externí odkaz:
https://doaj.org/article/4cc3d03906d04e20b154a4560d6445ca
Autor:
David Tes, Ahmed Aber, Mohsin Zafar, Luke Horton, Audrey Fotouhi, Qiuyun Xu, Ali Moiin, Andrew D Thompson, Tatiana Cristina Moraes Pinto Blumetti, Steven Daveluy, Wei Chen, Mohammadreza Nasiriavanaki
Publikováno v:
Biomedical Engineering and Computational Biology, Vol 9 (2018)
Background: Granular cell tumor (GCT) is a relatively uncommon tumor that may affect the skin. The tumor can develop anywhere on the body, although it is predominately seen in oral cavities and in the head and neck regions. Here, we present the resul
Externí odkaz:
https://doaj.org/article/39b546f591304601a215b99e167ccb44
Autor:
Ahmed Aber, Karl Kratkiewicz, Nour Arafat, Afreen Fatima, David Tes, Luke Horton, Mohsin Zafar, Mohammad Rn Avanaki
Publikováno v:
Biomedical Engineering and Computational Biology
Biomedical Engineering and Computational Biology, Vol 9 (2018)
Biomedical Engineering and Computational Biology, Vol 9 (2018)
Alzheimer disease is the most common form of dementia, affecting more than 5 million people in the United States. During the progression of Alzheimer disease, a particular protein begins to accumulate in the brain and also in extensions of the brain,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b30def75fe16e159f202df6464797a8f
Autor:
Sibylle Loibl, Chiun-Sheng Huang, Max S. Mano, Eleftherios P. Mamounas, Charles E. Geyer, Michael Untch, Jean-Christophe Thery, Ingo Schwaner, Steven Limentani, Niklas Loman, Kristina Lübbe, Jenny C. Chang, Thomas Hatschek, David Tesarowski, Chunyan Song, Sanne Lysbet de Haas, Thomas Boulet, Chiara Lambertini, Norman Wolmark
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-6 (2022)
Abstract Following chemotherapy and human epidermal growth factor 2 (HER2)-targeted neoadjuvant therapy for HER2-positive early breast cancer, residual invasive breast cancer at surgery may be HER2-negative on retesting in some patients. We evaluated
Externí odkaz:
https://doaj.org/article/c268c669d03547e1b3867ec85f83f413
Autor:
Konstantin Bob, David Teschner, Thomas Kemmer, David Gomez-Zepeda, Stefan Tenzer, Bertil Schmidt, Andreas Hildebrandt
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Mass spectrometry is an important experimental technique in the field of proteomics. However, analysis of certain mass spectrometry data faces a combination of two challenges: first, even a single experiment produces a large amoun
Externí odkaz:
https://doaj.org/article/7fbe9bcd7cb8405d93beb2c2c61ca1d5
Autor:
Ahmed Aber, Luke Horton, Andrew D Thompson, Qiuyun Xu, Mohsin Zafar, Steven Daveluy, David Tes, Mohammadreza Nasiriavanaki, Audrey Fotouhi, Ali Moiin, Wei Chen, Tatiana Blumetti
Publikováno v:
Biomedical Engineering and Computational Biology, Vol 9 (2018)
Biomedical Engineering and Computational Biology
Biomedical Engineering and Computational Biology
Background: Granular cell tumor (GCT) is a relatively uncommon tumor that may affect the skin. The tumor can develop anywhere on the body, although it is predominately seen in oral cavities and in the head and neck regions. Here, we present the resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8bc4023597dff893ef913045598a60
https://doi.org/10.1177/1179597218790250
https://doi.org/10.1177/1179597218790250
Autor:
Ryan M. Esquejo, Christopher T. Salatto, Jake Delmore, Bina Albuquerque, Allan Reyes, Yuji Shi, Rob Moccia, Emily Cokorinos, Matthew Peloquin, Mara Monetti, Jason Barricklow, Eliza Bollinger, Brennan K. Smith, Emily A. Day, Chuong Nguyen, Kieran F. Geoghegan, John M. Kreeger, Alan Opsahl, Jessica Ward, Amit S. Kalgutkar, David Tess, Lynne Butler, Norimitsu Shirai, Timothy F. Osborne, Gregory R. Steinberg, Morris J. Birnbaum, Kimberly O. Cameron, Russell A. Miller
Publikováno v:
EBioMedicine, Vol 31, Iss , Pp 122-132 (2018)
Dysregulation of hepatic lipid and cholesterol metabolism is a significant contributor to cardiometabolic health, resulting in excessive liver lipid accumulation and ultimately non-alcoholic steatohepatitis (NASH). Therapeutic activators of the AMP-A
Externí odkaz:
https://doaj.org/article/3a6b1a8ecd964eee8550aafb2b27ef05
Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm
Autor:
Marina Cerrone, Jerome Montnach, Xianming Lin, Yan-Ting Zhao, Mingliang Zhang, Esperanza Agullo-Pascual, Alejandra Leo-Macias, Francisco J. Alvarado, Igor Dolgalev, Thomas V. Karathanos, Kabir Malkani, Chantal J.M. Van Opbergen, Joanne J.A. van Bavel, Hua-Qian Yang, Carolina Vasquez, David Tester, Steven Fowler, Fengxia Liang, Eli Rothenberg, Adriana Heguy, Gregory E. Morley, William A. Coetzee, Natalia A. Trayanova, Michael J. Ackerman, Toon A.B. van Veen, Hector H. Valdivia, Mario Delmar
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
It is believed that mutations in desmosomal adhesion complex protein plakophilin 2 (PKP2) cause arrhythmia due to loss of cell-cell communication. Here the authors show that PKP2 controls the expression of proteins involved in calcium cycling in adul
Externí odkaz:
https://doaj.org/article/4417834a57fb40c18499881ece963bc6