Zobrazeno 1 - 10
of 23
pro vyhledávání: '"David T. Robles"'
Publikováno v:
American Journal of Clinical Dermatology. 12:1-6
Morgellons disease is a controversial and poorly defined symptom cluster of skin lesions and somatic symptoms, most notably 'fibers' in the skin. Because of widespread coverage in the media and on the Internet, there are an increasing number of patie
Publikováno v:
Dermatologic Surgery. 35:131-134
Autor:
David T. Robles, Philip Fleckman, Greg Wolgamot, Jennifer L. Leonard, Evan George, Alpana Waghmare, Nicholas L. Compton, Karen A. McDonough
Publikováno v:
Dermatology. 217:23-26
Doxycycline is a commonly prescribed medication for the management of acne vulgaris. Severe adverse reactions to this medication are uncommon. We describe an unusual case of a 20-year-old female who experienced a life-threatening hypersensitivity rea
Autor:
David T. Robles, Daniel Berg
Publikováno v:
Clinics in Dermatology. 25:26-32
Wound healing is a complex and carefully regulated physiologic response to a traumatic injury. Deregulation of this coordinated process can lead to exuberant scar formation as seen in keloids and hypertrophic scars. Despite their common occurrence, k
Autor:
David T. Robles, Akane Ide, Teodorica L. Bugawan, Marian Rewers, Henry A. Erlich, Sunanda R. Babu, Pamela R. Fain, George S. Eisenbarth, Tianbao Wang
Publikováno v:
Diabetes. 54:1879-1883
To evaluate potential differential diabetes risk of DR3 haplotypes we have evaluated class I alleles as well as two microsatellites previously associated with differential risk associated with DR3 haplotypes. We found that over one-third of patient D
Autor:
Carani B. Sanjeevi, Pam R. Fain, Liping Yu, Y.S. Park, Marian Rewers, David T. Robles, George S. Eisenbarth, Peter A. Gottlieb
Publikováno v:
Tissue Antigens. 60:155-163
Intra-MHC sequences including MHC class I chain-related genes (MICAs), D6S273 and D6S2223 are associated with autoimmune diseases in addition to HLA class II. In the current study, we ascertained the haplotypes of 57 Caucasian patients with Addison's
Publikováno v:
Endocrinology and Metabolism Clinics of North America. 31:353-368
A series of autoimmune disorders, often Addison's disease, type 1 diabetes mellitus, and thyroid autoimmunity, frequently occurs together in patients with the autoimmune polyendocrine syndrome type II (APS-II). The highest risk HLA genotype for Addis
Autor:
George S, Eisenbarth, Hiroaki, Moriyama, David T, Robles, Edwin, Liu, Liping, Yu, Sunanda, Babu, Maria J, Redondo, Maria, Redondo, Peter, Gottlieb, Dale, Wegmann, Marian, Rewers
Publikováno v:
Autoimmunity Reviews. 1:139-145
Type 1 diabetes of both the NOD mouse and man is associated with autoimmunity directed against insulin which is the only beta cell specific autoantigen identified to date. One can use autoantibodies to insulin to predict diabetes, use insulin peptide
Autor:
Liping Yu, Teodorica L. Bugawan, Sunanda R. Babu, David T. Robles, Marian Rewers, Jill M. Norris, Georgeanna J. Klingensmith, Henry A. Erlich, Michelle Hoffman, Tianbao Wang, Kathy Barriga, George S. Eisenbarth
Publikováno v:
Clinical Immunology. 102:217-224
A total of 21,000 general population newborns (NECs) and 693 young siblings-offspring of patients with type 1A diabetes (SOCs) were class II genotyped and 293 NECs and 72 SOCs with the high-risk genotype, DR3/4, DQB1*0302 have been prospectively eval
Autor:
George S. Eisenbarth, David T. Robles
Publikováno v:
Journal of Autoimmunity. 16:355-362
Type 1A diabetes is an immune mediated disorder that results from progressive destruction of the islet β-cells in the setting of genetic susceptibility. Both MHC and non-MHC genes contribute to disease with class II HLA molecules major determinants