Výsledky vyhledávání - "David T. Fung"

No evidence for collateral effects of electromagnetic fields used to increase dissolved oxygen levels on the behavior and physiology of freshwater fishes

Autor: Chris K. Elvidge, Christian J. Bihun, Colin Davis, Saad Ulhaq, David T. Fung, Jesse C. Vermaire, Steven J. Cooke

Publikováno v: Water Environment Research. 94

Hypoxia in surface waters driven by warming climate and other anthropogenic stressors is a major conservation concern, and technological solutions for water quality remediation are sorely needed. One potential solution involves the use of low-intensi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c75ef61c74bc94f4f193d16b1c0b526
https://doi.org/10.1002/wer.10747

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Advances in the development of gene therapy, noncoding RNA, and exosome-based treatments for tendinopathy

Autor: Angela Wang Ilaltdinov, Hui B. Sun, Yubao Gong, Daniel J. Leong, Konrad I. Gruson, Deyou Zheng, Li Sun, David T. Fung

Publikováno v: Annals of the New York Academy of SciencesReferences. 1490(1)

Tendinopathy is a common musculoskeletal disorder characterized by chronic low-grade inflammation and tissue degeneration. Tendons have poor innate healing ability and there is currently no cure for tendinopathy. Studies elucidating mechanisms underl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f18ebb5d5bc6f38ceb0530a517220f3
https://pubmed.ncbi.nlm.nih.gov/32501571

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Cycle-dependent matrix remodeling gene expression response in fatigue-loaded rat patellar tendons

Autor: Vincent M. Wang, Jonathan P. Braman, Jelena Basta-Pljakic, Jonathan Y. Lee, Daniel J. Leong, Mitch B. Schaffler, Hui B. Sun, Yonghui Li, David T. Fung, Raymond A. Klug, Evan L. Flatow, Nelly Andarawis-Puri, Jedd B. Sereysky, Stephen J. Ros, Karl J. Jepsen

Publikováno v: Journal of Orthopaedic Research. 28:1380-1386

Expression profiling of selected matrix remodeling genes was conducted to evaluate differences in molecular response to low-cycle (100) and high-cycle (7,200) sub-failure-fatigue loading of patellar tendons. Using our previously developed in vivo pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452329d259dbf4f1520839f9a56b9f43
https://doi.org/10.1002/jor.21132

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Coordinate Regulation of IL-1β and MMP-13 in Rat Tendons Following Subrupture Fatigue Damage

Autor: Hui B. Sun, David T. Fung, Mitchell B. Schaffler, Yonghui Li, Robert J. Majeska, Evan L. Flatow

Publikováno v: Clinical Orthopaedics & Related Research. 466:1555-1561

Mechanical overloading is a major causative factor of tendinopathy; however, its underlying mechanisms are unclear. We hypothesized mechanical overloading would damage tendons and alter genes associated with tendinopathy in a load-dependent manner. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a67af56ccf77155ac40810beaa27fc
https://doi.org/10.1007/s11999-008-0278-4

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ACL Impingement Prediction Based on MRI Scans of Individual Knees

Autor: Li-Qun Zhang, David T. Fung, Ronald W. Hendrix, Jason L. Koh

Publikováno v: Clinical Orthopaedics & Related Research. 460:210-218

Although tibial external rotation and abduction do not load the ACL strongly in cadaver-based biomechanical studies, such knee positions are associated with ACL injuries in clinical practice. We hypothesized the ACL could be injured in such knee posi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc1ab10ac938d9d5376488c6c8a6d0f
https://doi.org/10.1097/blo.0b013e31804d2339

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A Knee-Specific Finite Element Analysis of the Human Anterior Cruciate Ligament Impingement against the Femoral Intercondylar Notch

Autor: David T. Fung, Yupeng Ren, Hyung-Soon Park, Li-Qun Zhang, Chulhyun Ahn

This work presents a finite element analysis of anterior cruciate ligament (ACL) impingement against the intercondylar notch during tibial external rotation and abduction, as a mechanism of noncontact ACL injuries. Experimentally, ACL impingement was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7baf207f7af82a19200932344250f202
https://europepmc.org/articles/PMC2900495/

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Second harmonic generation imaging and Fourier transform spectral analysis reveal damage in fatigue-loaded tendons

Autor: Karl J. Jepsen, Damien M. Laudier, David T. Fung, Mitchell B. Schaffler, Rumana Huq, Evan L. Flatow, Jelena Basta-Pljakic, Jedd B. Sereysky

Publikováno v: Annals of biomedical engineering. 38(5)

Conventional histologic methods provide valuable information regarding the physical nature of damage in fatigue-loaded tendons, limited to thin, two-dimensional sections. We introduce an imaging method that characterizes tendon microstructure three-d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c589d78e524fe40456518fa7f2043d7f
https://pubmed.ncbi.nlm.nih.gov/20232150

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