Zobrazeno 1 - 10
of 72
pro vyhledávání: '"David T Bolick"'
Autor:
Stacey L Burgess, Akihiko Oka, Bo Liu, David T Bolick, David Noah Oakland, Richard L Guerrant, Luther Bartelt
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 7, p e0007515 (2019)
Giardia lamblia is a common intestinal parasitic infection that although often acutely asymptomatic, is associated with debilitating chronic intestinal and extra-intestinal sequelae. In previously healthy adults, a primary sporadic Giardia infection
Externí odkaz:
https://doaj.org/article/9500da7ed4804102babefd82b74752fd
Autor:
Natasa Giallourou, Gregory L Medlock, David T Bolick, Pedro Hqs Medeiros, Solanka E Ledwaba, Glynis L Kolling, Kenneth Tung, Patricia Guerry, Jonathan R Swann, Richard L Guerrant
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1007083 (2018)
Campylobacter infections are among the leading bacterial causes of diarrhea and of 'environmental enteropathy' (EE) and growth failure worldwide. However, the lack of an inexpensive small animal model of enteric disease with Campylobacter has been a
Externí odkaz:
https://doaj.org/article/a428cde70ff34eba80fd09b32b983ceb
Autor:
Luther A Bartelt, David T Bolick, Glynis L Kolling, James K Roche, Edna I Zaenker, Ana M Lara, Francisco Jose Noronha, Carrie A Cowardin, John H Moore, Jerrold R Turner, Cirle A Warren, Gregory A Buck, Richard L Guerrant
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 7, p e0004820 (2016)
Cryptosporidium is a major cause of severe diarrhea, especially in malnourished children. Using a murine model of C. parvum oocyst challenge that recapitulates clinical features of severe cryptosporidiosis during malnutrition, we interrogated the eff
Externí odkaz:
https://doaj.org/article/f0edf21ea617435ea428c1422f1a8969
Autor:
Richard L Guerrant, Alvaro M Leite, Relana Pinkerton, Pedro H Q S Medeiros, Paloma A Cavalcante, Mark DeBoer, Margaret Kosek, Christopher Duggan, Andrew Gewirtz, Jonathan C Kagan, Anna E Gauthier, Jonathan Swann, Jordi Mayneris-Perxachs, David T Bolick, Elizabeth A Maier, Marjorie M Guedes, Sean R Moore, William A Petri, Alexandre Havt, Ila F Lima, Mara de Moura Gondim Prata, Josyf C Michaleckyj, Rebecca J Scharf, Craig Sturgeon, Alessio Fasano, Aldo A M Lima
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0158772 (2016)
Critical to the design and assessment of interventions for enteropathy and its developmental consequences in children living in impoverished conditions are non-invasive biomarkers that can detect intestinal damage and predict its effects on growth an
Externí odkaz:
https://doaj.org/article/ef20d7da711044f0ac7b01a43a096543
Autor:
John H Moore, Caio C D Pinheiro, Edna I Zaenker, David T Bolick, Glynis L Kolling, Edward van Opstal, Francisco J D Noronha, Pedro H Q S De Medeiros, Raphael S Rodriguez, Aldo A Lima, Richard L Guerrant, Cirle A Warren
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131829 (2015)
Clostridium difficile is a major identifiable and treatable cause of antibiotic-associated diarrhea. Poor nutritional status contributes to mortality through weakened host defenses against various pathogens. The primary goal of this study was to asse
Externí odkaz:
https://doaj.org/article/a659e1523f1c41f0953f5ae192cc10d0
Autor:
John H Moore, Caio C D Pinheiro, Edna I Zaenker, David T Bolick, Glynis L Kolling, Edward van Opstal, Francisco J D Noronha, Pedro H Q S De Medeiros, Raphael S Rodriguez, Aldo A Lima, Richard L Guerrant, Cirle A Warren
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137037 (2015)
Externí odkaz:
https://doaj.org/article/bffdf640d67448b7bfd108ee3d0c51d7
Autor:
Orleâncio G R Azevedo, David T Bolick, James K Roche, Relana F Pinkerton, Aldo A M Lima, Michael P Vitek, Cirle A Warren, Reinaldo B Oriá, Richard L Guerrant
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89562 (2014)
Apolipoliprotein E (apoE), a critical targeting protein in lipid homeostasis, has been found to have immunoinflammatory effects on murine models of infection and malnutrition. The effects of apoE in undernourished and Cryptosporidium parvum-infected
Externí odkaz:
https://doaj.org/article/d99aa34025844ac7a61aee2cf836975f
Autor:
David T Bolick, Tufeng Chen, Luís Antonio O Alves, Yixin Tong, Di Wu, Linwood T Joyner, Reinaldo B Oriá, Richard L Guerrant, Zheng Fu
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106902 (2014)
Nutritional deficiency and stress can severely impair intestinal architecture, integrity and host immune defense, leading to increased susceptibility to infection and cancer. Although the intestine has an inherent capability to adapt to environmental
Externí odkaz:
https://doaj.org/article/ec2b760c47f44f49af03fb4f76910deb
Autor:
Reinaldo B. Oriá, Deiziane V.S. Costa, Pedro Henrique Q.S. de Medeiros, Cássia R. Roque, Ronaldo P. Dias, Cirle A. Warren, David T. Bolick, Richard L. Guerrant
Publikováno v:
Brazilian Journal of Infectious Diseases, Vol 27, Iss 3, Pp 102776- (2023)
Cryptosporidiosis is a waterborne protozoal infection that may cause life-threatening diarrhea in undernourished children living in unsanitary environments. The aim of this study is to identify new biomarkers that may be related to gut-brain axis dys
Externí odkaz:
https://doaj.org/article/1109d467212442c49b302fe78a8ac747
Autor:
Deiziane V. S. Costa, Jae H. Shin, Sophia M. Goldbeck, David T. Bolick, Flavio S. Mesquita, Andrea V. Loureiro, Mônica J. Rodrigues-Jesus, Gerly A. C. Brito, Cirle A. Warren
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Increased risk of intestinal dysfunction has been reported in patients after Clostridioides difficile infection (CDI). Enteric glial cells (EGCs), a component of the enteric nervous system (ENS), contribute to gut homeostasis. Previous studies showed
Externí odkaz:
https://doaj.org/article/f5522727504340d6ad333a34dadebbd7