Zobrazeno 1 - 10
of 15
pro vyhledávání: '"David T Blake"'
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15342 (2011)
Adult learning-induced sensory cortex plasticity results in enhanced action potential rates in neurons that have the most relevant information for the task, or those that respond strongly to one sensory stimulus but weakly to its comparison stimulus.
Externí odkaz:
https://doaj.org/article/174a493d15824ad9b9b6a8609bbe7bd7
Autor:
Sanskriti Sasikumar, Melanie Cohn, Ariana Youm, Katherine Duncan, Alexandra Boogers, Antonio P. Strafella, David T. Blake, Alfonso Fasano
Publikováno v:
Brain Stimulation, Vol 16, Iss 6, Pp 1643-1645 (2023)
Externí odkaz:
https://doaj.org/article/be74b5a4db7e4a40a5209e4fea1bf4a3
Development and Characterization of a Micromagnetic Alternative to Cochlear Implant Electrode Arrays
Publikováno v:
IEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol 30, Pp 2116-2125 (2022)
To stimulate the auditory nerve, cochlear implants directly inject electrical current into surrounding tissue via an implanted electrode array. While many cochlear implant users achieve strong speech perception scores, there remains significant varia
Externí odkaz:
https://doaj.org/article/bd0d9d2b66f144bab72baa3a2f96cf79
Autor:
Hua Tang, Mitchell R. Riley, Balbir Singh, Xue-Lian Qi, David T. Blake, Christos Constantinidis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
It remains unclear whether improvements in one cognitive task transfer to other tasks. Here, the authors show that changes in prefrontal neuronal activation, firing rate, and local field potentials induced during active learning of a working memory t
Externí odkaz:
https://doaj.org/article/595ef811838a48b4a1550dec055b28d4
Autor:
Xue-Lian Qi, Kendyl R. Pennington, Christopher Banerjee, Fernando L. Vale, Sarah K. Bick, Dario J. Englot, Robert S. Turner, Christos Constantinidis, David T. Blake
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101136- (2022)
Summary: We present an experimental protocol to record neuronal activity during intermittent stimulation of nucleus basalis (NB), as macaque monkeys perform cognitive tasks. This protocol includes implantation of electrodes and generator devices to d
Externí odkaz:
https://doaj.org/article/835d90a81b3c42fb9d36a0718668b94c
Autor:
Jacob Kumro, Ashutosh Tripathi, Yun Lei, Jeremy Sword, Patrick Callahan, Alvin Terry, Xin-yun Lu, Sergei A Kirov, Anilkumar Pillai, David T Blake
Publikováno v:
Cerebral Cortex.
The etiology of Alzheimer’s dementia has been hypothesized in terms of basal forebrain cholinergic decline, and in terms of reflecting beta-amyloid neuropathology. To study these different biological elements, we activated the basal forebrain in 5x
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3ef35cb292b5b03148c94b0944eb1b6
https://doi.org/10.1093/cercor/bhad066
https://doi.org/10.1093/cercor/bhad066
Publikováno v:
Communicative & Integrative Biology, Vol 10, Iss 5-6 (2017)
The brain's cholinergic arousal pathways decline in parallel with the brain's executive functions in aging and Alzheimer's Disease. The frontline and currently most effective approach to treating Alzheimer's disease is the administration of cholinest
Externí odkaz:
https://doaj.org/article/afd77f36e3e44501890eddfce3375176
Autor:
Jacob Kumro, Ashutosh Tripathi, Yun Lei, Jeremy Sword, Patrick Callahan, Alvin Terry, Xin-yun Lu, Sergei Kirov, Anilkumar Pillai, David T Blake
The biological basis of Alzheimer’s dementia has been hypothesized in terms of basal forebrain cholinergic decline, and in terms reflecting the neuropathologies surrounding beta amyloid and tau. To shed light on the contributions of these different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f05a6a4f0501cc03878d44625d1deffc
https://doi.org/10.1101/2022.03.04.482983
https://doi.org/10.1101/2022.03.04.482983
Autor:
David T Blake
Publikováno v:
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 132(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ddf9324c0267a1ba6cf719ec5481f4
https://pubmed.ncbi.nlm.nih.gov/34226125
https://pubmed.ncbi.nlm.nih.gov/34226125
Autor:
Hua Tang, Mitchell R. Riley, Balbir Singh, Xue-Lian Qi, David T. Blake, Christos Constantinidis
Publikováno v:
Nature Communications
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Training in working memory tasks is associated with lasting changes in prefrontal cortical activity. To assess the neural activity changes induced by training, we recorded single units, multi-unit activity (MUA) and local field potentials (LFP) with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc780ae8d1156205dbfe29f44357590e
https://pubmed.ncbi.nlm.nih.gov/35013248
https://pubmed.ncbi.nlm.nih.gov/35013248