Zobrazeno 1 - 10
of 126
pro vyhledávání: '"David T, Yang"'
Publikováno v:
Clinical Case Reports, Vol 8, Iss 12, Pp 3302-3309 (2020)
Abstract B‐cell lymphomas with atypical presentation or immunophenotype pose diagnostic challenges. Conventional ancillary tests (cytogenetics, FISH) can help, but have technical limitations. New technologies such as mate‐pair sequencing (MPSeq)
Externí odkaz:
https://doaj.org/article/d79b427b13454517a03574cfa861e8df
Autor:
Hamidullah Khan, Ashish Anshu, Aman Prasad, Sushmita Roy, Justin Jeffery, Wasakorn Kittipongdaja, David T. Yang, Stefan M. Schieke
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 3009-3018.e4 (2019)
Summary: Metabolic flexibility allows cells to adapt to various environments and limits the efficacy of metabolic drugs. Therapeutic targeting of cancer metabolism relies on defining limiting requirements and vulnerabilities in the highly dynamic met
Externí odkaz:
https://doaj.org/article/553eb4e3b9a748c286cfdb7fef8f791d
Autor:
Lixin Rui, Christian M. Capitini, Thomas A. Waldmann, Madelyn Chen, Samantha Bebel, Apoorv Kondapelli, Alexander Rosiejka, Yangguang Li, Yunxia Liu, Amanda Kelm, David T. Yang, Shanxiang Zhang, Anusara Daenthanasanmak, Paul D. Bates, Fen Zhu, Nguyet M. Hoang, Li Lu, Shuichi Kimpara
Supplementary Methods, Supplementary Figures and Figure Legends. Figure S1. EGR1 is a downstream target of BCR and JAK1 signaling (related to Figure 1). Figure S2. Sensitivity of MCL cell lines to EGR1 shRNAs and statistical analysis (related to Figu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3090fbe8e8e01eb05a340f7ecd43dd
https://doi.org/10.1158/1541-7786.22527053
https://doi.org/10.1158/1541-7786.22527053
Autor:
Lixin Rui, Christian M. Capitini, Thomas A. Waldmann, Madelyn Chen, Samantha Bebel, Apoorv Kondapelli, Alexander Rosiejka, Yangguang Li, Yunxia Liu, Amanda Kelm, David T. Yang, Shanxiang Zhang, Anusara Daenthanasanmak, Paul D. Bates, Fen Zhu, Nguyet M. Hoang, Li Lu, Shuichi Kimpara
Early growth response gene (EGR1) is a transcription factor known to be a downstream effector of B-cell receptor signaling and Janus kinase 1 (JAK1) signaling in diffuse large B-cell lymphoma (DLBCL). While EGR1 is characterized as a tumor suppressor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7fc4f731aa0924678a485fd314a9541
https://doi.org/10.1158/1541-7786.c.6545306.v1
https://doi.org/10.1158/1541-7786.c.6545306.v1
Autor:
Lixin Rui, Christian M. Capitini, Thomas A. Waldmann, Madelyn Chen, Samantha Bebel, Apoorv Kondapelli, Alexander Rosiejka, Yangguang Li, Yunxia Liu, Amanda Kelm, David T. Yang, Shanxiang Zhang, Anusara Daenthanasanmak, Paul D. Bates, Fen Zhu, Nguyet M. Hoang, Li Lu, Shuichi Kimpara
Supplementary Table S1 including analyzed RNA-seq and ChIP-seq data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e067120d4d6228b04ec19938a9eaf06
https://doi.org/10.1158/1541-7786.22527050
https://doi.org/10.1158/1541-7786.22527050
Autor:
Ross L. Levine, Jing Zhang, Fabao Liu, Alexis Vedder, Xin Gao, Sergey Nikolaev, Mrinal M. Patnaik, Abhishek A. Mangaonkar, Yun Zhou, Kalyan Vara Ganesh Nadiminti, Anthony M. Hunter, Terra L. Lasho, Wei Xu, Evan Flietner, Erik A. Ranheim, Xiaona You, Ruiqi Liao, Klaus Geissler, Eric Padron, Nathalie Droin, Guangyao Kong, Moritz Binder, Eric Solary, Maria E. Balasis, Christy Finke, Britta Will, Omar Abdel-Wahab, Adhithi Rajagopalan, Zhi Wen, David T. Yang
Publikováno v:
Blood
Mutations in chromatin regulator ASXL1 are frequently identified in myeloid malignancies, in particular ∼40% of patients with chronic myelomonocytic leukemia (CMML). ASXL1 mutations are associated with poor prognosis in CMML and significantly co-oc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48bb19333aa8d11e90688ba3955306c7
https://doi.org/10.1182/blood.2021012519
https://doi.org/10.1182/blood.2021012519
Autor:
Paul F. Lambert, Gregory K. Hartig, Timothy M. McCulloch, David T. Yang, Denis Lee, Laurel D. Lorenz, Molly A. Smith, Grace C. Blitzer, Eric A. Armstrong, Menggang Yu, Benjamin J. Soriano, Robert Z. Yang, Alexandra D. Torres, Paul M. Harari, Randall J. Kimple
PDF file - 384K, Detection of multiple HPV subtypes by degenerate PCR of genomic DNA (A) or by HPV-16 specific Southern blot (B).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b6b442f274e3ef2b6979363a55aeb4
https://doi.org/10.1158/1078-0432.22449423
https://doi.org/10.1158/1078-0432.22449423
Autor:
Paul F. Lambert, Gregory K. Hartig, Timothy M. McCulloch, David T. Yang, Denis Lee, Laurel D. Lorenz, Molly A. Smith, Grace C. Blitzer, Eric A. Armstrong, Menggang Yu, Benjamin J. Soriano, Robert Z. Yang, Alexandra D. Torres, Paul M. Harari, Randall J. Kimple
XLSX file - 37K, Primer sequences used.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5c66b10de1cc71ddd4e8def296f2f3
https://doi.org/10.1158/1078-0432.22449420.v1
https://doi.org/10.1158/1078-0432.22449420.v1
Autor:
Paul F. Lambert, Gregory K. Hartig, Timothy M. McCulloch, David T. Yang, Denis Lee, Laurel D. Lorenz, Molly A. Smith, Grace C. Blitzer, Eric A. Armstrong, Menggang Yu, Benjamin J. Soriano, Robert Z. Yang, Alexandra D. Torres, Paul M. Harari, Randall J. Kimple
Purpose: To develop a clinically relevant model system to study head and neck squamous cell carcinoma (HNSCC), we have established and characterized a direct-from-patient tumorgraft model of human papillomavirus (HPV)–positive and HPV-negative canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065220addc201d9da55a1435dc564348
https://doi.org/10.1158/1078-0432.c.6521655.v1
https://doi.org/10.1158/1078-0432.c.6521655.v1
Autor:
Adam L Bailey, Connor R Buechler, Daniel R Matson, Eric J Peterson, Kevin G Brunner, Mariel S Mohns, Meghan Breitbach, Laurel M Stewart, Adam J Ericsen, Christina M Newman, Michelle R Koenig, Emma Mohr, John Tan, Saverio Capuano, Heather A Simmons, David T Yang, David H O'Connor
Publikováno v:
PLoS Pathogens, Vol 13, Iss 10, p e1006692 (2017)
Human pegivirus (HPgV) protects HIV+ people from HIV-associated disease, but the mechanism of this protective effect remains poorly understood. We sequentially infected cynomolgus macaques with simian pegivirus (SPgV) and simian immunodeficiency viru
Externí odkaz:
https://doaj.org/article/6ca40416db514a84b26864e30f9bf3cf