Zobrazeno 1 - 10
of 28
pro vyhledávání: '"David Szafron"'
Patterns and outcomes of subsequent therapy after immune checkpoint inhibitor discontinuation in HCC
Autor:
Rohini Sharma, Anjana Pillai, Thomas Urban Marron, Petros Fessas, Anwaar Saeed, Tomi Jun, Sirish Dharmapuri, David Szafron, Abdul Rafeh Naqash, Anuhya Gampa, Yinghong Wang, Uqba Khan, Mahvish Muzaffar, Chieh‐Ju Lee, Pei‐Chang Lee, Anushi Bulumulle, Sonal Paul, Dominic Bettinger, Hannah Hildebrand, Mohammed Yehia, Tiziana Pressiani, Ahmed Kaseb, Yi‐Hsiang Huang, Celina Ang, Masatoshi Kudo, Naoshi Nishida, Nicola Personeni, Lorenza Rimassa, David James Pinato
Publikováno v:
Hepatology Communications, Vol 6, Iss 7, Pp 1776-1785 (2022)
Abstract The availability of immune checkpoint inhibitors (ICIs) for the management of advanced hepatocellular cancer (HCC) has changed the treatment paradigm. There are emerging questions regarding the efficacy of subsequent anticancer therapies. Th
Externí odkaz:
https://doaj.org/article/e44c4fda0f48434e9cdc4675c1f8ec5f
Publikováno v:
Case Reports in Gastroenterology, Vol 16, Iss 2, Pp 388-393 (2022)
Encorafenib, a BRAF kinase inhibitor, in combination with binimetinib, a selective MEK inhibitor have known gastrointestinal adverse events; however, adverse colitis events have not been well studied. We report a case series of 4 patients with melano
Externí odkaz:
https://doaj.org/article/a9e594ea6db34f619f410877e1a9a9d1
Autor:
Petros Fessas, Muntaha Naeem, Matthias Pinter, Thomas U. Marron, David Szafron, Lorenz Balcar, Anwaar Saeed, Tomi Jun, Sirish Dharmapuri, Anuhya Gampa, Yinghong Wang, Uqba Khan, Mahvish Muzaffar, Musharraf Navaid, Pei-Chang Lee, Anushi Bulumulle, Bo Yu, Sonal Paul, Neil Nimkar, Dominik Bettinger, Hannah Hildebrand, Yehia I. Abugabal, Tiziana Pressiani, Nicola Personeni, Naoshi Nishida, Masatoshi Kudo, Ahmed Kaseb, Yi-Hsiang Huang, Celina Ang, Anjana Pillai, Lorenza Rimassa, Abdul Rafeh Naqash, Elad Sharon, Alessio Cortellini, David J. Pinato
Publikováno v:
Liver Cancer, Vol 10, Iss 6, Pp 583-592 (2021)
Background and Rationale: Immune checkpoint inhibitor (ICI) therapy is an expanding therapeutic option for hepatocellular carcinoma (HCC). Antibiotics (ATB) taken prior to or early during ICI therapy can impact immunotherapy efficacy across indicatio
Externí odkaz:
https://doaj.org/article/5b2616ec247c4eb78946d132559d4210
Autor:
Dominik Bettinger, Bo Yu, David Szafron, Yinghong Wang, Mahvish Muzaffar, Thomas Marron, Uqba Khan, Yi-Hsiang Huang, David J Pinato, Ahmed Kaseb, Anwaar Saeed, Tomi Jun, Sirish Dharmapuri, Musharraf Navaid, ChiehJu Lee, Anushi Bulumulle, Sonal Paul, Petros Fessas, Neil Nimkar, Hannah Hildebrand, Tiziana Pressiani, Yehia I Abugabal, Nicola Personeni, Lorenza Rimassa, Celina Ang, Abdul Rafeh Naqash, Francesca Benevento
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Nivolumab is Food and Drug Administration approved in sorafenib-experienced, advanced hepatocellular carcinoma (HCC). Post-registration data of treatment in a real-world setting is lacking.Patients and methods We performed an international
Externí odkaz:
https://doaj.org/article/a6f7c74dd48f4d2982a8f93cab08e973
Autor:
Dominik Bettinger, Bo Yu, David Szafron, Yinghong Wang, Abdul Rafeh Naqash, Mahvish Muzaffar, Uqba Khan, Yi-Hsiang Huang, David J Pinato, Ahmed Kaseb, Anwaar Saeed, Tomi Jun, Sirish Dharmapuri, Musharraf Navaid, ChiehJu Lee, Anushi Bulumulle, Sonal Paul, Petros Fessas, Neil Nimkar, Hannah Hildebrand, Tiziana Pressiani, Yehia I Abugabal, Nicola Personeni, Jingky Lozano-Kuehne, Lorenza Rimassa, Celina Ang, Thomas U Marron
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
The impact of corticosteroid therapy (CT) on efficacy of immune checkpoint inhibitors (ICI) is undefined in hepatocellular carcinoma (HCC). We evaluated whether CT administered at baseline (bCT) or concurrently with ICI (cCT) influences overall (OS),
Externí odkaz:
https://doaj.org/article/fd5dfa2eba3b4f96a6696a68a05a1a49
Autor:
Mohammed S. Hussein, Isaac Raijman, Joseph T. Krill, Hashem B. El–Serag, Mohamed O. Othman, Sherif Elhanafi, William E. Fisher, Kalpesh Patel, David Szafron
Publikováno v:
Digestive Diseases and Sciences. 67:3244-3251
Diffuse echogenicity of the pancreas, a commonly discovered finding on endoscopic ultrasound (EUS), is often of undetermined significance. The goal of this study was to characterize the clinical picture and pancreatic function in patients who inciden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d485cdffc2ec8fc356563dbcd83c2322
https://doi.org/10.1007/s10620-021-07181-1
https://doi.org/10.1007/s10620-021-07181-1
Autor:
Hamzah Abu‐Sbeih, David Szafron, Ahmed A. Elkafrawy, Victor Garcia‐Rodriguez, Weijie Ma, Ann Xu, Shruti Khurana, Laith Numan, Ellie Chen, Ryan Goldstein, Adrianne Tsen, Yuanzun Peng, Mariela Blum, Edmund S Kopetz, Naruhiko Ikoma, Malek Shatila, Wei Qiao, Gottumukkala S. Raju, William A Ross, Phillip S Ge, Emmanuel Coronel, Yinghong Wang
Publikováno v:
Journal of gastroenterology and hepatologyReferences. 37(10)
The diagnosis and treatment of gastrointestinal (GI) bleeding secondary to malignancy can be challenging. Endoscopy is the gold standard to diagnose and treat gastrointestinal bleeding but clinical characteristics and outcomes of patients with malign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874534ec421ee91e1db61075fa649f62
https://pubmed.ncbi.nlm.nih.gov/35730192
https://pubmed.ncbi.nlm.nih.gov/35730192
Patterns and outcomes of subsequent therapy after immune checkpoint inhibitor discontinuation in HCC
Autor:
Rohini Sharma, Anjana Pillai, Thomas Urban Marron, Petros Fessas, Anwaar Saeed, Tomi Jun, Sirish Dharmapuri, David Szafron, Abdul Rafeh Naqash, Anuhya Gampa, Yinghong Wang, Uqba Khan, Mahvish Muzaffar, Chieh‐Ju Lee, Pei‐Chang Lee, Anushi Bulumulle, Sonal Paul, Dominic Bettinger, Hannah Hildebrand, Mohammed Yehia, Tiziana Pressiani, Ahmed Kaseb, Yi‐Hsiang Huang, Celina Ang, Masatoshi Kudo, Naoshi Nishida, Nicola Personeni, Lorenza Rimassa, David James Pinato
Publikováno v:
Hepatology communications. 6(7)
The availability of immune checkpoint inhibitors (ICIs) for the management of advanced hepatocellular cancer (HCC) has changed the treatment paradigm. There are emerging questions regarding the efficacy of subsequent anticancer therapies. The primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd08d66a500f9e6a9ec14fa36c045cb1
https://pubmed.ncbi.nlm.nih.gov/35481940
https://pubmed.ncbi.nlm.nih.gov/35481940
Publikováno v:
American Journal of Gastroenterology. 117:e432-e432
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fd8d0361de74434627a888397e10b9f
https://doi.org/10.14309/01.ajg.0000859120.28729.06
https://doi.org/10.14309/01.ajg.0000859120.28729.06
Autor:
Kirsten B. Goldberg, Thomas U. Marron, Yutao Gong, Chieh J. Lee, Celina Ang, Pallavi S. Mishra-Kalyani, Tiziana Pressiani, Thoetchai Peeraphatdit, Lola Fashoyin-Aje, Anushi Bulumulle, Elad Sharon, Mahvish Muzaffar, Alessio Cortellini, Pei Chang Lee, Ahmed Kaseb, David J. Pinato, Steven Lemery, Uqba Khan, Anwaar Saeed, Sonal Paul, Yinghong Wang, Yehia I. Abugabal, Bo Yu, Tomi Jun, Sirish Dharmapuri, Nicola Personeni, Lorenza Rimassa, Antonio D'Alessio, Guo Wei, Marc R. Theoret, Musharraf Navaid, Anuhya Gampa, Richard Pazdur, Hannah Hildebrand, Abdul Rafeh Naqash, Neil Nimkar, Yi Hsiang Huang, David Szafron, Julie A. Schneider, Lorraine Pelosof, Dominik Bettinger, Anjana Pillai
Publikováno v:
European journal of cancer (Oxford, England : 1990). 157
Purpose The development of treatment-related adverse events (trAE) correlates favorably with clinical outcomes in multiple studies of patients receiving immune checkpoint inhibitors (ICI); however, this relationship is undefined in patients with hepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8909bf74242d4341dbc3ae7fad9413cf
https://pubmed.ncbi.nlm.nih.gov/34508996
https://pubmed.ncbi.nlm.nih.gov/34508996