Zobrazeno 1 - 10
of 87
pro vyhledávání: '"David Strutt"'
Publikováno v:
iScience, Vol 17, Iss , Pp 49-66 (2019)
Summary: In developing tissues, sheets of cells become planar polarized, enabling coordination of cell behaviors. It has been suggested that “signaling” of polarity information between cells may occur either bidirectionally or monodirectionally b
Externí odkaz:
https://doaj.org/article/40cab3b0c3784dbd9045661f93d3af6f
Autor:
Helen Strutt, David Strutt
Publikováno v:
Open Biology, Vol 11, Iss 2 (2021)
Planar polarity describes the coordinated polarization of cells within the plane of a tissue. This is controlled by two main pathways in Drosophila: the Frizzled-dependent core planar polarity pathway and the Fat–Dachsous pathway. Components of bot
Externí odkaz:
https://doaj.org/article/dc2e84e4a30646ee8fdd8100f5558a41
Autor:
Helen Strutt, David Strutt
Publikováno v:
PLoS Genetics, Vol 16, Iss 8, p e1008820 (2020)
The core planar polarity proteins are essential mediators of tissue morphogenesis, controlling both the polarised production of cellular structures and polarised tissue movements. During development the core proteins promote planar polarisation by be
Externí odkaz:
https://doaj.org/article/e3550c20fdb7495dad973d4277ae5573
Publikováno v:
eLife, Vol 8 (2019)
The conserved core planar polarity pathway is essential for coordinating polarised cell behaviours and the formation of polarised structures such as cilia and hairs. Core planar polarity proteins localise asymmetrically to opposite cell ends and form
Externí odkaz:
https://doaj.org/article/319abdbb911849ba8d6913724fa71b34
Publikováno v:
Cell Reports, Vol 25, Iss 6, Pp 1415-1424.e6 (2018)
Summary: Planar polarity, the coordinated polarization of cells in the plane of a tissue, is important for normal tissue development and function. Proteins of the core planar polarity pathway become asymmetrically localized at the junctions between c
Externí odkaz:
https://doaj.org/article/77f9a03cb63943d78456c5905f7e75c7
Publikováno v:
Biology Open, Vol 5, Iss 4, Pp 397-408 (2016)
The epidermal patterns of all three larval instars (L1–L3) of Drosophila are made by one unchanging set of cells. The seven rows of cuticular denticles of all larval stages are consistently planar polarised, some pointing forwards, others backwards
Externí odkaz:
https://doaj.org/article/537fe38a211040fcbf9050a40fcdb509
Publikováno v:
eLife, Vol 4 (2015)
To understand how long-range patterning gradients are interpreted at the cellular level, we investigate how a gradient of expression of the Four-jointed kinase specifies planar polarised distributions of the cadherins Fat and Dachsous in the Drosophi
Externí odkaz:
https://doaj.org/article/ead8554ac2c949d383dfbc35633341cc
Publikováno v:
PLoS Genetics, Vol 9, Iss 7, p e1003654 (2013)
The core planar polarity proteins are required to specify the orientation of structures that are polarised in the plane of the epithelium. In the Drosophila melanogaster wing, the core proteins localise asymmetrically at either proximal or distal cel
Externí odkaz:
https://doaj.org/article/2e29b072b19643b8a2785a61d79df9a0
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e65076 (2013)
Extensive morphogenetic remodelling takes place during metamorphosis from a larval to an adult insect body plan. These changes are particularly intricate in the generation of the dipteran wing hinge, a complex structure that is derived from an appare
Externí odkaz:
https://doaj.org/article/e7fe045c88604e0da38e1213debbd241
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2438
Here, we present a detailed protocol for fluorescence recovery after photobleaching (FRAP) to measure the dynamics of junctional populations of proteins in living tissue. Specifically, we describe how to perform FRAP in Drosophila pupal wings on fluo