Zobrazeno 1 - 8
of 8
pro vyhledávání: '"David Serreze"'
Autor:
Leire Egia-Mendikute, Berta Arpa, Estela Rosell-Mases, Marta Corral-Pujol, Jorge Carrascal, Jorge Carrillo, Conchi Mora, Harold Chapman, Anaïs Panosa, Marta Vives-Pi, Thomas Stratmann, David Serreze, Joan Verdaguer
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Previous studies indicate that B-lymphocytes play a key role activating diabetogenic T-lymphocytes during the development of autoimmune diabetes. Recently, two transgenic NOD mouse models were generated: the NOD-PerIg and the 116C-NOD mice. In NOD-Pe
Externí odkaz:
https://doaj.org/article/0b9a8aef91974cd5bdd2c8480e4e4c01
Autor:
Felix Scheuplein, Deanna J Lamont, Matthew E Poynter, Jonathan E Boyson, David Serreze, Lennart K A Lundblad, Robert Mashal, Robert Schaub
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140729 (2015)
Invariant Natural Killer T (iNKT) cells are a T cell subset expressing an invariant T Cell Receptor (TCR) that recognizes glycolipid antigens rather than peptides. The cells have both innate-like rapid cytokine release, and adaptive-like thymic posit
Externí odkaz:
https://doaj.org/article/6980faa195b94b189f29fc0fda87c8e0
Publikováno v:
Frontiers Research Topics ISBN: 9782832507445
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67db13b0132d0667053ff5959d2d82a
https://doi.org/10.3389/978-2-8325-0744-5
https://doi.org/10.3389/978-2-8325-0744-5
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes
Autor:
Matthew C. Funsten, Leonid A. Yurkovetskiy, Andrey Kuznetsov, Derek Reiman, Camilla H.F. Hansen, Katharine I. Senter, Jean Lee, Jeremy Ratiu, Shiva Dahal-Koirala, Dionysios A. Antonopoulos, Gary M. Dunny, Ludvig M. Sollid, David Serreze, Aly A. Khan, Alexander V. Chervonsky
Publikováno v:
Cell Host & Microbe. 31:213-227.e9
Diet and commensals can affect the development of autoimmune diseases like type 1 diabetes (T1D). However, whether dietary interventions are microbe-mediated was unclear. We found that a diet based on hydrolyzed casein (HC) as a protein source protec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5074285ea72b9ccbfa3894cda5f5292e
https://doi.org/10.1016/j.chom.2022.12.009
https://doi.org/10.1016/j.chom.2022.12.009
Publikováno v:
The Journal of Immunology. 202:50.6-50.6
β-cell destruction in type 1 diabetes (T1D) is considered a T-cell mediated autoimmune disease, but based on studies in the NOD mouse model, B-lymphocytes also play a critical pathogenic role. They do so by serving as a preferential subset of pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef1727da2350ca073b91cdb736b32a1c
https://doi.org/10.4049/jimmunol.202.supp.50.6
https://doi.org/10.4049/jimmunol.202.supp.50.6
Autor:
Caroline McPhee Leeth, Muneer Hasham, Jeremy Ratiu, Jing Zhu, Harry Chapman, Jane Branca, Kevin Mills, David Serreze
Publikováno v:
The Journal of Immunology. 196:47.6-47.6
While CD4+ and CD8+ T lymphocytes are ultimately responsible for the destruction of insulin-producing beta cells resulting in clinical type 1 diabetes (T1D), B lymphocytes are also critical pathogenic players in T1D development in NOD mice and likely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5229f116954d101dd18ed4f9b3b3a60
https://doi.org/10.4049/jimmunol.196.supp.47.6
https://doi.org/10.4049/jimmunol.196.supp.47.6
Autor:
Caroline Leeth, Harry Chapman, Berta Arpa, jorge carrillo, Jorge Carrascal, Estela Rosell, Joan Verdaguer, David Serreze
Publikováno v:
The Journal of Immunology. 194:46.4-46.4
Type 1 diabetes (T1D) results from the destruction of insulin-producing pancreatic ß-cells by autoreactive CD4+ and CD8+ T-cells culminating in glucose dysregulation in both humans and the NOD mouse model. It is clear in the NOD mouse model and also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48023748eed2347bb0eeeb93323b4576
https://doi.org/10.4049/jimmunol.194.supp.46.4
https://doi.org/10.4049/jimmunol.194.supp.46.4
Publikováno v:
The Journal of Immunology. 188:171.43-171.43
Despite sharing the H2g7 MHC, the closely NOD-related NOR strain remains type 1 diabetes (T1D) resistant due to the presence of protective Idd5.2, Idd9/11, and Idd13 loci. We previously showed that CD4-T cells isolated from the Idd9/11 congenic strai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26a999b1050f3c1381680a5a92dce627
https://doi.org/10.4049/jimmunol.188.supp.171.43
https://doi.org/10.4049/jimmunol.188.supp.171.43