Zobrazeno 1 - 8
of 8
pro vyhledávání: '"David Serota"'
Impurity Qualification Toxicology Study for a 2′-O-Methoxyethyl-Modified Antisense Inhibitor in Mice
Autor:
Andrew McPherson, Scott P. Henry, David Serota, Daniel C. Capaldi, Christine Hoffmaster, Nhuy Luu, Farah Mahdi, Tae-Won Kim, Andrew A. Rodriguez, Chris Papagiannis
Publikováno v:
Nucleic Acid Therapeutics. 30:14-21
Safety assessment of drug impurities is a routine part of the drug development process. For oligonucleotide-based drugs, impurities can arise from impurities in starting materials, as by-products of the manufacturing process or from degradation, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f99d214878773961d132295dbdea87
https://doi.org/10.1089/nat.2019.0780
https://doi.org/10.1089/nat.2019.0780
Publikováno v:
Journal of Student-Run Clinics. 8
Background: The student-run Infectious Disease Elimination Act (IDEA) Clinic serves people who inject drugs (PWID) by providing human immunodeficiency virus testing, hepatitis C virus testing, wound care, cutaneous abscess treatment, safe injection e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::231a5aa6759afe28ce7c2565951b1c94
https://doi.org/10.59586/jsrc.v8i1.281
https://doi.org/10.59586/jsrc.v8i1.281
Autor:
Lijiang Shen, David Serota, Shin-Young Park, Yunlip Kim, Tae-Won Kim, Scott P. Henry, Thomas A. Zanardi, Chris Papagiannis
Publikováno v:
Nucleic Acid Therapeutics. 28:233-241
Advances in antisense oligonucleotide (ASO) chemistry and screening have enabled the design and selection of molecules that are optimized for a particular therapeutic application in terms of both potency and tolerability. The most-well studied of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e80347a09bd5880bea4914003221101
https://doi.org/10.1089/nat.2017.0706
https://doi.org/10.1089/nat.2017.0706
Autor:
Germaine Cuff, Jung T. Kim, David Serota, Amber A. Guth, Deborah Axelrod, Michael Wajda, Michael Schlame, Alex Bekker
Publikováno v:
Pain Practice. 6:273-277
� Abstract: This study compared the analgesic efficacy of postoperative lavender oil aromatherapy in 50 patients undergoing breast biopsy surgery. Twenty-five patients received supplemental oxygen through a face mask with two drops of 2% lavender o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d4fc2e32e79f0118b64d8340075ca2
https://doi.org/10.1111/j.1533-2500.2006.00095.x
https://doi.org/10.1111/j.1533-2500.2006.00095.x
Autor:
Dale Cooper, Gregory W. Ruppert, Lisa Craig, David Serota, Christopher Papagiannis, Duane Poage
Publikováno v:
Hayes' Principles and Methods of Toxicology, Sixth Edition ISBN: 9781842145364
Hayes' Principles and Methods of Toxicology, Sixth Edition
Hayes' Principles and Methods of Toxicology, Sixth Edition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c709fb70460157676691b43cfe7cda3
https://doi.org/10.1201/b17359-24
https://doi.org/10.1201/b17359-24
Publikováno v:
The Role of the Study Director in Nonclinical Studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2199f1c35bf89bdf4a3e6d62d279aa57
https://doi.org/10.1002/9781118873922.ch4
https://doi.org/10.1002/9781118873922.ch4
Autor:
Tracy Pickering, Rachel Tapp, Scott Wilson, Rose Kovalcsik, Jonelle May, Travis Devlin, David Serota, Melissa Martinek, Sheryl Loux
Publikováno v:
Lab animal. 35(9)
Research scientists and IACUC members are faced with the difficult task of balancing the necessity of using animals for experimental research and their mandate to protect the welfare of those animals used in that research. One way to reduce the numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ac5e9a89319dcfbf565cc6885f2beb
https://pubmed.ncbi.nlm.nih.gov/17008909
https://pubmed.ncbi.nlm.nih.gov/17008909
Autor:
Qiuyan Zhao, David Serota, James Heath, Zhiwei Jiang, Herschel Giles, Carolyn Oliver, Sudhir Agrawal
Publikováno v:
Antisensenucleic acid drug development. 7(6)
The aim of the present study is to evaluate the in vivo toxicologic effects of a phosphorothioate oligodeoxynucleotide (PS oligo) and three of its analogs [PS oligo containing four methylphosphonate linkages at the 3' and 5'-ends (MBO 1), PS oligo co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::535b6a44d0f3842514bc1b76e2621c11
https://pubmed.ncbi.nlm.nih.gov/9450915
https://pubmed.ncbi.nlm.nih.gov/9450915