Zobrazeno 1 - 8
of 8
pro vyhledávání: '"David Sentelle"'
Autor:
Besim Ogretmen, M. Ozgur Cevik, Monzur Murshed, Zohreh Khavandgar, Jacqueline M. Kraveka, Michael Nishimura, Telma Martins da Palma, Haakan Norell, Yusuf A. Hannun, Christopher J. Clarke, Sahar A. Saddoughi, R. David Sentelle, Salih Gencer, Jocelyn A. Lewis, Marisa Meyers-Needham
PDF file, 712KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a9fccb9005e6122aa1d57c4aeda4f26
https://doi.org/10.1158/1535-7163.22498867.v1
https://doi.org/10.1158/1535-7163.22498867.v1
Autor:
Besim Ogretmen, M. Ozgur Cevik, Monzur Murshed, Zohreh Khavandgar, Jacqueline M. Kraveka, Michael Nishimura, Telma Martins da Palma, Haakan Norell, Yusuf A. Hannun, Christopher J. Clarke, Sahar A. Saddoughi, R. David Sentelle, Salih Gencer, Jocelyn A. Lewis, Marisa Meyers-Needham
PDF file, 101KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed53ace47377516634066f230601f43
https://doi.org/10.1158/1535-7163.22498864.v1
https://doi.org/10.1158/1535-7163.22498864.v1
Autor:
Venkat K. Ramshesh, R. David Sentelle, Zdzislaw M. Szulc, Salih Gencer, Wenhui Jiang, Can E. Senkal, Shanmugam Panneer Selvam, Yuri K. Peterson, Jacek Bielawski, Suriyan Ponnusamy, John J. Lemasters, Besim Ogretmen
Publikováno v:
Nature chemical biology
Mechanisms by which autophagy promotes cell survival or death are unclear. We provide evidence that C(18)-pyridinium ceramide treatment or endogenous C(18)-ceramide generation by ceramide synthase 1 (CerS1) expression mediates autophagic cell death,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dcea2fd9751c8cbde39a599aacfbf49
https://doi.org/10.1038/nchembio.1059
https://doi.org/10.1038/nchembio.1059
Autor:
Christopher R. Gault, Arelis Salas, Joshua J. Oaks, Yusuf Baran, Besim Ogretmen, Robert K. Stuart, Ramasamy Santhanam, Guido Marcucci, Danilo Perrotti, Suriyan Ponnusamy, Elif Apohan, Lina M. Obeid, Hesham M. El-Shewy, Daniel J. Fernandes, Marisa Meyers-Needham, Sandeep Mahajan, Sahar A. Saddoughi, Shanmugam Panneer Selvam, Can E. Senkal, R. David Sentelle, Charles D. Smith
Publikováno v:
Blood. 117:5941-5952
The mechanisms by which sphingosine kinase-1 (SK-1)/sphingosine 1-phosphate (S1P) activation contributes to imatinib resistance in chronic myeloid leukemia (CML) are unknown. We show herein that increased SK-1/S1P enhances Bcr-Abl1 protein stability,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ba74c280d6d383ca8042691be9ea57
https://doi.org/10.1182/blood-2010-08-300772
https://doi.org/10.1182/blood-2010-08-300772
Autor:
Haakan R Norell, Besim Ogretmen, Marisa Meyers-Needham, Monzur Murshed, Jacqueline M. Kraveka, Telma Martins da Palma, Salih Gencer, Michael Nishimura, Yusuf A. Hannun, Jocelyn A. Lewis, R. David Sentelle, M. Ozgur Cevik, Christopher J. Clarke, Sahar A. Saddoughi, Zohreh Khavandgar
Publikováno v:
Molecular cancer therapeutics. 11(5)
Sonic hedgehog (SHh) signaling is important in the pathogenesis of various human cancers, such as medulloblastomas, and it has been identified as a valid target for anticancer therapeutics. The SHh inhibitor cyclopamine induces apoptosis. The bioacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77287a4e0113e2740d8a34053a47a851
https://pubmed.ncbi.nlm.nih.gov/22452947
https://pubmed.ncbi.nlm.nih.gov/22452947
Autor:
Marisa Meyers-Needham, David Sentelle, Arelis Salas, Besim Ogretmen, Shanmugam Panneer Selvam, Suriyan Ponnusamy, Sahar A. Saddoughi, Can E. Senkal
Sphingolipids have emerged as bioeffector molecules, controlling various aspects of cell growth and proliferation in cancer, which is becoming the deadliest disease in the world. These lipid molecules have also been implicated in the mechanism of act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd14fac5467e391b03ceaa005009a5b
https://europepmc.org/articles/PMC3071292/
https://europepmc.org/articles/PMC3071292/
Autor:
R David Sentelle, Can E Senkal, Wenhui Jiang, Suriyan Ponnusamy, Salih Gencer, Shanmugam Panneer Selvam, Venkat K Ramshesh, Yuri K Peterson, John J Lemasters, Zdzislaw M Szulc, Jacek Bielawski, Besim Ogretmen
Publikováno v:
Nature Chemical Biology. 8:1008-1008
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d128c951bd3972bd5723adf55b2d595b
https://doi.org/10.1038/nchembio1212-1008c
https://doi.org/10.1038/nchembio1212-1008c
Publikováno v:
Cancer Research. 71:2875-2875
Sphingolipid ceramide is a bioeffector molecule involved in the regulation of cell death. Endogenous ceramides contain different fatty acid chain lengths varying between C12-C26-ceramides. Ceramide synthase 1 (CerS1) selectively regulates the generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e13096ccc0df9a0ec07c7975013057c1
https://doi.org/10.1158/1538-7445.am2011-2875
https://doi.org/10.1158/1538-7445.am2011-2875