Zobrazeno 1 - 10
of 18
pro vyhledávání: '"David Sehy"'
Autor:
Ron Schultheis, Se Hwan Lee, Nelson Santiago, Aniruddha Puntambekar, Jungyoup Han, Chong H. Ahn, Junhai Kai, David Sehy
Publikováno v:
Procedia Engineering. 25:651-656
Immunoassays and enzyme-linked immunosorbent assays (ELISA) are one of the key technologies for the quantification of a wide range of analytes for serum, plasma and cell lysates. The protocols of the immunoassays have not changed significantly for ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56cfd04787aa1dbcf23f8d3195a2b93
https://doi.org/10.1016/j.proeng.2011.12.162
https://doi.org/10.1016/j.proeng.2011.12.162
Autor:
Christopher A. Hunter, David Sehy, Sara T. Passos, Aisling C. O’Hara, Jonathan S. Silver, Jason S. Stumhofer
Publikováno v:
The Journal of Immunology. 184:1776-1783
Previous studies have implicated T cell production of IL-17 in resistance to Toxoplasma gondii as well as the development of immune-mediated pathology during this infection. Analysis of C57BL/6 and C57BL/6 RAG−/− mice challenged with T. gondii-id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b0778f9e2b171aa6607d4cb386fac0
https://doi.org/10.4049/jimmunol.0901843
https://doi.org/10.4049/jimmunol.0901843
Autor:
David Sehy, Creg J. Workman, Yao Wang, Dario A. A. Vignali, Kelli L. Boyd, Lauren W. Collison, Richard L. Cross, Kate M. Vignali, Richard S. Blumberg, Timothy T. Kuo
Publikováno v:
Nature. 450:566-569
Regulatory T cells suppress immune function by direct cell to cell contact and secretion of the cytokines IL-10 and TGF-β. In this paper, a novel member of the IL-12 cytokine family that contributes to Treg function is identified. Regulatory T (Treg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e5939ac57acfd97ed9c37489ed2ce5
https://doi.org/10.1038/nature06306
https://doi.org/10.1038/nature06306
Autor:
Jean Maguire van Seventer, John A. Meyers, Calvin F. Roff, Alyson J. Mangini, David Sehy, Taro Nagai, Gijs A. van Seventer
Publikováno v:
Cytokine. 35:235-246
Type I interferons (IFN) (IFN-alpha/beta) are recognized as both inhibitors and effectors of autoimmune disease. In multiple sclerosis, IFN-beta therapy appears beneficial, in part, due to its suppression of autoimmune inflammatory Th cell responses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df2c8e79cce799e045bcb94be5ae26ea
https://doi.org/10.1016/j.cyto.2006.09.001
https://doi.org/10.1016/j.cyto.2006.09.001
Autor:
Junhai Kai, Se Hwan Lee, Victor Moore, Aniruddha Puntambekar, Chong H. Ahn, David Sehy, Nelson Santiago, Jungyoup Han
Publikováno v:
Lab on a chip. 12(21)
In this work we introduce a novel microfluidic enzyme linked immunoassays (ELISA) microplate as the next generation assay platform for unparalleled assay performances. A combination of microfluidic technology with standard SBS-configured 96-well micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5a67f3cf28fc7f2eb4dc6a08872632
https://pubmed.ncbi.nlm.nih.gov/22914859
https://pubmed.ncbi.nlm.nih.gov/22914859
Autor:
Chong H. Ahn, Jungyoup Han, Ron Schultheis, David Sehy, Aniruddha Puntambekar, Nelson Santiago, Victor Moore, Junhai Kai, Montaha Lakkis, Se Hwan Lee
Publikováno v:
Translational Medicine.
Miniaturized, high throughput detection technologies including microfluidics systems represent powerful tools for biomarker discovery and analysis. Optimiser™ microplate technology combines microfluidics technology with standard SBS-configured 96-w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9a4b2afab21d1ef2d91433609ab03b6
https://doi.org/10.4172/2161-1025.s1-006
https://doi.org/10.4172/2161-1025.s1-006
Publikováno v:
Leukemia Research. 17:247-253
Lipophilic cationic compounds accumulate more rapidly in the mitochondria of many carcinoma-derived cells than in non-transformed cells, thus leading to their pronounced cytotoxic effects on carcinoma cells. In this report, in order to measure tumori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e939c28f2c38036cadb31eaaa2b571f
https://doi.org/10.1016/0145-2126(93)90008-9
https://doi.org/10.1016/0145-2126(93)90008-9
Autor:
Matthias Ernst, Christopher A. Hunter, Akihiko Yoshimura, Cristina M. Tato, Elaine Huang, Lothar Hennighausen, Leanne M. Johnson, John J. O'Shea, Alejandro V. Villarino, Emma H. Wilson, Qiulong Huang, David Sehy, Christiaan J. M. Saris, Arian Laurence, Jason S. Stumhofer
Publikováno v:
Nature immunology. 7(9)
Studies have focused on the events that influence the development of interleukin 17 (IL-17)-producing T helper cells (T(H)-17 cells) associated with autoimmunity, such as experimental autoimmune encephalitis, but relatively little is known about the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284f6d74bf7612455b8e8138dd574d02
https://pubmed.ncbi.nlm.nih.gov/16924249
https://pubmed.ncbi.nlm.nih.gov/16924249
Publikováno v:
Current Protocols in Immunology
Because most cytokines are utilized, catabolized, or excreted shortly after they are produced, it has been difficult to directly measure in vivo cytokine production. Consequently, it has been necessary to infer in vivo cytokine secretion levels from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47e1f23c17fed94347eb73980279706
https://doi.org/10.1002/0471142735.im0628s54
https://doi.org/10.1002/0471142735.im0628s54
Publikováno v:
Genetic Engineering & Biotechnology News. 31:26-27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6e41b22dc3832b4bb5c3053d0690150
https://doi.org/10.1089/gen.31.18.10
https://doi.org/10.1089/gen.31.18.10