Výsledky vyhledávání - "David Schiffmann"

Akademický článek

Retrograde Analysis of Calcium Signaling by CaMPARI2 Shows Cytosolic Calcium in Chondrocytes Is Unaffected by Parabolic Flights

Autor: Andreas Hammer, Geraldine Cerretti, Dario A. Ricciardi, David Schiffmann, Simon Maranda, Raphael Kummer, Christoph Zumbühl, Karin F. Rattenbacher-Kiser, Silvan von Arx, Sebastian Ammann, Frederic Strobl, Rayene Berkane, Alexandra Stolz, Ernst H. K. Stelzer, Marcel Egli, Enrico Schleiff, Simon L. Wuest, Maik Böhmer

Publikováno v: Biomedicines, Vol 10, Iss 1, p 138 (2022)

Calcium (Ca2+) elevation is an essential secondary messenger in many cellular processes, including disease progression and adaptation to external stimuli, e.g., gravitational load. Therefore, mapping and quantifying Ca2+ signaling with a high spatiot

Externí odkaz: https://doaj.org/article/20eed5d6622e47309604c2af82478b5c

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Akademický článek

Tumorigenic fragments of APC cause dominant defects in directional cell migration in multiple model systems

Autor: Scott A. Nelson, Zhouyu Li, Ian P. Newton, David Fraser, Rachel E. Milne, David M. A. Martin, David Schiffmann, Xuesong Yang, Dirk Dormann, Cornelis J. Weijer, Paul L. Appleton, Inke S. Näthke

Publikováno v: Disease Models & Mechanisms, Vol 5, Iss 6, Pp 940-947 (2012)

SUMMARY Nonsense mutations that result in the expression of truncated, N-terminal, fragments of the adenomatous polyposis coli (APC) tumour suppressor protein are found in most sporadic and some hereditary colorectal cancers. These mutations can caus

Externí odkaz: https://doaj.org/article/1e574324a2d14d30b041a92d115daf7e

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Accelerated and long-time creep testing of extruded polystyrene using isothermal and stepped isothermal method

Autor: David Schiffmann, Willy Villasmil, Sebastian Ammann, Hans Simmler, Jörg Worlitschek, Ludger Fischer

Seasonal Sensible Thermal Energy Storages based on existing inside structures are cost effective and require insulation materials with high performance. The insulation must endure high temperatures and high pressure for a long period. In this study,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2fe55c583312c056123f31ffb25ab6

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Retrograde Analysis of Calcium Signaling by CaMPARI2 Shows Cytosolic Calcium in Chondrocytes Is Unaffected by Parabolic Flights

Autor: Böhmer, Andreas Hammer, Geraldine Cerretti, Dario A. Ricciardi, David Schiffmann, Simon Maranda, Raphael Kummer, Christoph Zumbühl, Karin F. Rattenbacher-Kiser, Silvan von Arx, Sebastian Ammann, Frederic Strobl, Rayene Berkane, Alexandra Stolz, Ernst H. K. Stelzer, Marcel Egli, Enrico Schleiff, Simon L. Wuest, Maik

Publikováno v: Biomedicines; Volume 10; Issue 1; Pages: 138

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::70604276e5570e9f2c205a1480bc6723

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Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis

Autor: Inke S. Näthke, Valerie Meniel, Ian P. Newton, Abigail Oakley, David Schiffmann, Dina Dikovskaya, Owen J. Sansom, Thomas Jamieson, Karin Kroboth, Alan Richard Clarke

Publikováno v: The Journal of Cell Biology

Mutations in the adenomatous polyposis coli (APC) tumor suppressor gene initiate a majority of colorectal cancers. Acquisition of chromosomal instability is an early event in these tumors. We provide evidence that the loss of APC leads to a partial l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f76fae3c5b7256bd077a817db895da
http://europepmc.org/articles/PMC2063938

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Open microscopy environment and findspots: integrating image informatics with quantitative multidimensional image analysis

Autor: Ian P. Newton, Ilya G. Goldberg, Douglas A. Creager, Chris Allan, David Schiffmann, Inke S. Näthke, Dina Dikovskaya, Paul L. Appleton

Publikováno v: BioTechniques. 41(2)

Biomedical research and drug development increasingly involve the extraction of quantitative data from digital microscope images, such as those obtained using fluorescence microscopy. Here, we describe a novel approach for both managing and analyzing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c73a7e867963f074fab4d85bf8074f7
https://pubmed.ncbi.nlm.nih.gov/16925022

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Correction: Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis

Autor: Abigail Oakley, Dina Dikovskaya, Inke S. Näthke, Valerie Meniel, Thomas Jamieson, David Schiffmann, Karin Kroboth, Alan Richard Clarke, Owen J. Sansom, Ian P. Newton

Publikováno v: Journal of Cell Biology. 176:369-369

Vol. 176 No. 2, January 15, 2007. Pages [183–195][1]. The authors appear in the incorrect order on the first page of this article. The correct author line appears below. Dina Dikovskaya, David Schiffman, Ian P. Newton, Abigail Oakley, Karin Kroboth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a3fe23cadc84482b4ba60a4b1f98ec7
https://doi.org/10.1083/jcb.20061009920070116c

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