Zobrazeno 1 - 10
of 45
pro vyhledávání: '"David Schieltz"'
Autor:
John R Barr, Zsuzsanna Kuklenyik, Michael Gardner, Christopher Toth, Bryan A Parks, Jeffery Jones, David Schieltz, Michael Andrews, Jon Rees, Lisa McWilliams, James L Pirkle
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
A multiplexed, quantitative analytical workflow was applied to 120 fasting human serum samples collected from 30 normolipidemic, and 90 dyslipidemic donors. The analysis included separation by asymmetric flow field-flow fractionation while collecting
Autor:
Bryan A Parks, Susan Kuklenyik, David Schieltz, Christopher Toth, Michael Andrews, Jeffrey Jones, Michael Gardner, Jon Rees, Lisa McWilliams, John R Barr
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Hypertriglyceridemia is frequently observed with diabetes mellitus (DM) and is associated with increased cardiovascular disease (CVD) risk. In conditions of insulin deficiency or resistance, increased levels of free fatty acids are seen by the liver,
Autor:
David Schieltz, Zsuzsanna Kuklenyik, Bryan A Parks, Michael Gardner, Christopher Toth, Jeffrey Jones, Michael Andrews, Jon Rees, Lisa McWilliams, John Barr, Jim L Pirkle
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Clearance of elevated triglycerides (TG) level in response to fat challenge is a clinically significant indicator of CVD risk. HDL can play a key role in facilitating TG metabolism explaining the reverse correlation of HDL levels with CVD risk. In th
Publikováno v:
Molecular Biology of the Cell
Protein phosphatase 2A (PP2A) is a key regulator of mitosis, but the roles that it plays are poorly understood. New evidence in budding yeast shows that the Zds proteins form a tight stoichiometric complex with PP2A and target its activity to the Cdc
Publikováno v:
Proceedings of the National Academy of Sciences. 102:8478-8482
Histone acetyltransferases have been shown to participate in many essential cellular processes, particularly those associated with activation of transcription. SAGA (Spt-Ada-Gcn5 acetyltransferase) and SLIK (SAGA-like) are two highly homologous multi
Publikováno v:
Nature. 433:434-438
The specific post-translational modifications to histones influence many nuclear processes including gene regulation, DNA repair and replication. Recent studies have identified effector proteins that recognize patterns of histone modification and tra
Publikováno v:
ELECTROPHORESIS. 25:2003-2009
We report on microbore liquid chromatography (microLC) and capillary electrophoresis (CE) separation of glycopeptides and high-mannose-type oligosaccharides, digested from recombinant phospholipase C, expressed in Pichia pastoris. The glycopeptides w
Autor:
Jeremy A. Daniel, Zu-Wen Sun, David Schieltz, C. David Allis, John R. Yates, Patrick A. Grant, Michael S Torok
Publikováno v:
Journal of Biological Chemistry. 279:1867-1871
Post-translational modifications of the histone protein components of eukaryotic chromatin play an important role in the regulation of chromatin structure and gene expression (1). Given the requirement of Rad6/Bre1-dependent ubiquitination of histone
Publikováno v:
Molecular Cell. 7(1):13-20
The evolutionarily conserved yeast checkpoint protein kinase Rad53 regulates cell cycle progression, transcription, and DNA repair in response to DNA damage. To uncover potential regulatory targets of Rad53, we identified proteins physically associat